Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lisa Käshammer"'
Autor:
Lisa Käshammer, Fusinita van den Ent, Magnus Jeffery, Nicolas L. Jean, Victoria L. Hale, Jan Löwe
Publikováno v:
Nature Microbiology.
Autor:
Lisa Käshammer, Fusinita van den Ent, Magnus Jeffery, Nicolas L. Jean, Victoria L. Hale, Jan Löwe
Cell division, or cytokinesis is a fundamental process of life and, in most bacteria, is driven by peptidoglycan synthesis at the septum1. It is catalysed by the divisome, a multi-protein complex with more than 20 components that spans the cell envel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::156b671ef5e5ec52de918f0bde755d87
https://doi.org/10.1101/2022.11.21.517367
https://doi.org/10.1101/2022.11.21.517367
Autor:
Fabian, Gut, Lisa, Käshammer, Katja, Lammens, Joseph D, Bartho, Anna-Maria, Boggusch, Erik, van de Logt, Brigitte, Kessler, Karl-Peter, Hopfner
Publikováno v:
Molecular Cell. 82:3513-3522.e6
DNA double-strand breaks (DSBs) threaten genome stability and are linked to tumorigenesis in humans. Repair of DSBs requires the removal of attached proteins and hairpins through a poorly understood but physiologically critical endonuclease activity
Publikováno v:
Nucleic Acids Research
The Mre11–Rad50 complex is a DNA double-strand break sensor that cleaves blocked DNA ends and hairpins by an ATP-dependent endo/exonuclease activity for subsequent repair. For that, Mre11–Rad50 complexes, including the Escherichia coli homolog Sb
Autor:
Joseph Bartho, Karl-Peter Hopfner, Jan-Hinnerk Saathoff, Brigitte Kessler, Aaron Alt, Fabian Gut, Katja Lammens, Lisa Käshammer
Publikováno v:
Molecular Cell. 76:382-394.e6
Summary DNA double-strand breaks (DSBs) threaten genome stability throughout life and are linked to tumorigenesis in humans. To initiate DSB repair by end joining or homologous recombination, the Mre11-nuclease Rad50-ATPase complex detects and proces