Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lisa J. Wilcox"'
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 5, Pp 725-734 (2001)
The citrus flavonoids, naringenin and hesperetin, lower plasma cholesterol in vivo. However, the underlying mechanisms are not fully understood. The ability of these flavonoids to modulate apolipoprotein B (apoB) secretion and cellular cholesterol ho
Externí odkaz:
https://doaj.org/article/12a515d9e08c4a66a0daefaeb45f563c
Autor:
John R. Burnett, Lisa J. Wilcox, Dawn E. Telford, Sandra J. Kleinstiver, P. Hugh R. Barrett, Roger S. Newton, Murray W. Huff
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 7, Pp 1317-1327 (1999)
An orally bioavailable acyl coenzyme A:cholesterol acyltransferase (ACAT) inhibitor, avasimibe (CI-1011), was used to test the hypothesis that inhibition of cholesterol esterification, in vivo, would reduce hepatic very low density (VLDL) apolipoprot
Externí odkaz:
https://doaj.org/article/8db4818fc6fd46e5a7b38427c73ee6f8
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 6, Pp 1078-1089 (1999)
The concept that hepatic cholesterol synthesis regulates hepatocyte assembly and secretion of apoB-containing lipoproteins remains controversial. The present study was carried out in HepG2 cells to examine the regulation of apoB secretion by the HMG-
Externí odkaz:
https://doaj.org/article/c8bfed8f30674e3798c42c07f663de10
Autor:
Brook Wharton, Stephen L. Sturley, Lisa J. Wilcox, Dina A. Balderes, Govinda Rao, Arthur H. Tinkelenberg
Publikováno v:
Journal of Biological Chemistry. 277:32466-32472
In contrast to lipoprotein-mediated sterol uptake, free sterol influx by eukaryotic cells is poorly understood. To identify components of non-lipoprotein-mediated sterol uptake, we utilized strains of Saccharomyces cerevisiae that accumulate exogenou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11725ef1647c01bf18135a74859f346
https://doi.org/10.1074/jbc.m204707200
https://doi.org/10.1074/jbc.m204707200
Autor:
Dawn E. Telford, S. J. Kleinstiver, John R. Burnett, Lisa J. Wilcox, Murray W. Huff, P. Hugh R. Barrett, Roger S. Newton
Publikováno v:
Endocrinology. 140:5293-5302
It has been postulated that the rate of hepatic very low density lipoprotein (VLDL) apolipoprotein (apo) B secretion is dependent upon the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. To test this hypothesis in vivo, apoB ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::841d2bb06363e6e1869dcb81c0aa1b79
https://doi.org/10.1210/endo.140.11.7150
https://doi.org/10.1210/endo.140.11.7150
Autor:
Murray W. Huff, P. Hugh R. Barrett, Roger S. Newton, John R. Burnett, Dawn E. Telford, Lisa J. Wilcox, S. J. Kleinstiver
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 7, Pp 1317-1327 (1999)
An orally bioavailable acyl coenzyme A:cholesterol acyltransferase (ACAT) inhibitor, avasimibe (CI-1011), was used to test the hypothesis that inhibition of cholesterol es- terification, in vivo, would reduce hepatic very low density (VLDL) apolipopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00739ad0574f257a0a130c85f9ef4f7b
https://doi.org/10.1016/s0022-2275(20)33494-5
https://doi.org/10.1016/s0022-2275(20)33494-5
Publikováno v:
Cardiovascular Drug Reviews. 17:160-178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c65ddadf5078b7c7199577eeab8c9ba7
https://doi.org/10.1111/j.1527-3466.1999.tb00011.x
https://doi.org/10.1111/j.1527-3466.1999.tb00011.x
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 6, Pp 1078-1089 (1999)
The concept that hepatic cholesterol synthesis regulates hepatocyte assembly and secretion of apoB-containing lipoproteins remains controversial. The present study was carried out in HepG2 cells to examine the regulation of apoB secretion by the HMG-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ccd2362894dd21e760642e1ee46b81
https://doi.org/10.1016/s0022-2275(20)33512-4
https://doi.org/10.1016/s0022-2275(20)33512-4
Autor:
John R. Burnett, P.H.R. Barrett, Lisa J. Wilcox, Dawn E. Telford, Murray W. Huff, S. J. Kleinstiver, Roger S. Newton
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:2589-2600
Abstract In the present studies, the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor atorvastatin was used to test the hypothesis that inhibition of cholesterol biosynthesis in vivo with a consequent reduction in the availability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c89a5510741571704ee8c8e82c56e97
https://doi.org/10.1161/01.atv.17.11.2589
https://doi.org/10.1161/01.atv.17.11.2589
Diets containing the soya-derived phytoestrogens, genistein and daidzein, decrease plasma cholesterol in humans and experimental animals. The mechanisms responsible for the hypocholesterolaemic effects of these isoflavones are unknown. The present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a0a6274c72d064fa03dc98cf1badb4
https://europepmc.org/articles/PMC1222800/
https://europepmc.org/articles/PMC1222800/
