Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lisa J. Whalen"'
Autor:
Melinda R. Hoyt, Gillian I. Falcon, Charles J. Pearce, Robert E. Delaney, Tyler E. Stevens, Emily M. Johnson, Thomas M. Szenderski, Nathan R. Sorenson, Sydney F. Fultz-Waters, Mark A. Rodriguez, Lisa J. Whalen, Todd C. Monson
Publikováno v:
Frontiers in Materials, Vol 10 (2023)
Soft magnetic composites (SMCs) offer a promising alternative to electrical steels and soft ferrites in high performance motors and power electronics. They are ideal for incorporation into passive electronic components such as inductors and transform
Externí odkaz:
https://doaj.org/article/0456f9789db54e1c80f06ccf87211f61
Publikováno v:
Synlett. 30:104-108
As part of ongoing research to investigate structural requirements for lactate dehydrogenase inhibition by highly substituted naphthoic acids, nine new aryl-substituted dihydroxynaphthoic acids were synthesized from three known precursors. Described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f288897e1ba02575e343b9b6fd158ad9
https://doi.org/10.1055/s-0037-1611342
https://doi.org/10.1055/s-0037-1611342
Autor:
Lucy A. Hunsaker, Lorraine M. Deck, David L. Vander Jagt, Thomas A. Vander Jagt, Lisa J. Whalen, Robert E. Royer
Publikováno v:
European Journal of Medicinal Chemistry. 143:854-865
Inflammation and oxidative stress are common in many chronic diseases. Targeting signaling pathways that contribute to these conditions may have therapeutic potential. The transcription factor Nrf2 is a major regulator of phase II detoxification and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283db546f09fcf027c5c7e0403000d37
https://doi.org/10.1016/j.ejmech.2017.11.048
https://doi.org/10.1016/j.ejmech.2017.11.048
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:1423-1430
Nrf2, which is a member of the cap'n'collar family of transcription factors, is a major regulator of phase II detoxification and anti-oxidant genes as well as anti-inflammatory and neuroprotective genes. The importance of inflammation and oxidative s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd95dd0fdc67d8a5e541031da39bb940
https://doi.org/10.1016/j.bmc.2017.01.005
https://doi.org/10.1016/j.bmc.2017.01.005
Autor:
Elizabeth R. Bright, David L. Vander Jagt, Robert E. Royer, Jacob A. Greenberg, Taylor S. Busby, Lorraine M. Deck, Lisa J. Whalen
Publikováno v:
Tetrahedron Letters. 54:6015-6018
As part of ongoing research to investigate structural requirements for lactate dehydrogenase inhibition by highly substituted naphthoic and indenoic acids, certain naphthalene and indene precursors to those types of compounds are required. Described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::197983e2fedf14daaf8edd85c19db420
https://doi.org/10.1016/j.tetlet.2013.08.067
https://doi.org/10.1016/j.tetlet.2013.08.067
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:8386-8395
Several model mechanism-based inhibitors (MbIs) were designed and evaluated for their ability to inhibit sulfatases. The MbI motifs were based on simple aromatic sulfates, which are known to be commonly accepted substrates across this highly conserve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874c9bd480693d548d89788908cf0f77
https://doi.org/10.1016/j.bmc.2006.09.002
https://doi.org/10.1016/j.bmc.2006.09.002
Publikováno v:
Advanced Synthesis & Catalysis. 348:2555-2559
Dihydroxyacetone phosphate (DHAP)-dependent aldolases have been widely used for the organic synthesis of unnatural sugars or derivatives. The practicality of using DHAP-dependent aldolases is limited by their strict substrate specificity and the high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d04ca23be059f60db31f30f8e4ac2f8
https://doi.org/10.1002/adsc.200600356
https://doi.org/10.1002/adsc.200600356
Autor:
Lisa J. Whalen, Randall L. Halcomb
Publikováno v:
Organic Letters. 6:3221-3224
[reaction: see text] A route for the synthesis of an electrophilic, carbocyclic galactose equivalent from D-galactose is described. The strategy utilizes ring-closing metathesis with Grubbs's second-generation catalyst as the key step. The galactose-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c3f08fbbf373ffd848919ee25b5834
https://doi.org/10.1021/ol0490779
https://doi.org/10.1021/ol0490779
Autor:
Elizabeth R. Bright, Jacob A. Greenberg, Lorraine M. Deck, David L. Vander Jagt, Lisa J. Whalen, Taylor S. Busby, Robert E. Royer
Publikováno v:
ChemInform. 45
As part of ongoing research to investigate structural requirements for lactate dehydrogenase inhibition by highly substituted naphthoic and indenoic acids, certain naphthalene and indene precursors to those types of compounds are required. Described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d0f268abd356ba4167e7dfab5a06df5
https://doi.org/10.1002/chin.201412083
https://doi.org/10.1002/chin.201412083
Autor:
Cary J. Morrow, Lisa J. Whalen
Publikováno v:
Tetrahedron: Asymmetry. 11:1279-1288
A simple approach to the resolution of chiral alcohols through a lipase-catalyzed transesterification of one enantiomer of the corresponding trifluoroethyl carbonate by a low molecular weight poly(ethylene glycol), PEG, is described. The method was d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e912456a2f46d2265ee34b38bfa0f4d
https://doi.org/10.1016/s0957-4166(00)00068-9
https://doi.org/10.1016/s0957-4166(00)00068-9