Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Lisa J Lapidus"'
Autor:
Bercem Dutagaci, Grzegorz Nawrocki, Joyce Goodluck, Ali Akbar Ashkarran, Charles G Hoogstraten, Lisa J Lapidus, Michael Feig
Publikováno v:
eLife, Vol 10 (2021)
Phase separation processes are increasingly being recognized as important organizing mechanisms of biological macromolecules in cellular environments. Well-established drivers of phase separation are multi-valency and intrinsic disorder. Here, we sho
Externí odkaz:
https://doaj.org/article/0c745aff409643c69df18eb2b28da9ec
Autor:
Lisa J Lapidus
Publikováno v:
F1000Research, Vol 6 (2017)
In this review, I discuss the various methods researchers use to unfold proteins in the lab in order to understand protein folding both in vitro and in vivo. The four main techniques, chemical-, heat-, pressure- and force-denaturation, produce distin
Externí odkaz:
https://doaj.org/article/bb0a053f2e54480faf84d074d6fe4733
Publikováno v:
Journal of chemical theory and computation.
Biomolecular condensation, especially liquid-liquid phase separation, is an important physical process with relevance for a number of different aspects of biological functions. Key questions of what drives such condensation, especially in terms of mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b239314995956e782e0ddbeb165ad17
https://pubmed.ncbi.nlm.nih.gov/36607820
https://pubmed.ncbi.nlm.nih.gov/36607820
Autor:
Gilberto Valdes-Garcia, Kasun Gamage, Casey Smith, Karina Martirosova, Michael Feig, Lisa J. Lapidus
Understanding the thermodynamics that drives liquid-liquid phase separation (LLPS) is quite important given the many numbers of diverse biomolecular systems undergoing this phenomenon. Regardless of the diversity, the processes underlying the formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73d2fd472bf65d88ac5397f7c8fee911
https://doi.org/10.1101/2022.11.21.517354
https://doi.org/10.1101/2022.11.21.517354
Publikováno v:
The journal of physical chemistry letters. 13(43)
Transient protein-protein interactions occur frequently under the crowded conditions encountered in biological environments, yet they remain poorly understood. Here, tryptophan-cysteine quenching is introduced as an experimental approach that is idea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1505eb6aef66ef17c09677be09969dd6
https://pubmed.ncbi.nlm.nih.gov/36279257
https://pubmed.ncbi.nlm.nih.gov/36279257
Autor:
Gilberto Valdes-Garcia, Kasun Gamage, Casey Smith, Karina Martirosova, Michael Feig, Lisa J. Lapidus
Publikováno v:
Cell Reports Physical Science. 4:101415
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58180831595aabe82f6329d2749cfcb6
https://doi.org/10.1016/j.xcrp.2023.101415
https://doi.org/10.1016/j.xcrp.2023.101415
Autor:
Lisa J. Lapidus
Publikováno v:
The Biophysicist. 2:30-39
In this article, I describe a new curriculum for introductory physics for the life sciences, a 2-semester sequence usually required of all biology majors. Because biology-related applications on the macroscale are complex and require mathematics beyo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0123edd235851ed7b11f31c8dfe184f
https://doi.org/10.35459/tbp.2019.000138
https://doi.org/10.35459/tbp.2019.000138
Autor:
Lisa J. Lapidus, David Witalka
Publikováno v:
Protein Folding ISBN: 9781071617151
Observation of protein folding on submillisecond time scales requires specialized ultra-rapid mixers coupled to optical or chemical probes. Here we describe the protocol for employing a microfabricated mixer with a mixing time of 8 μs coupled to a U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88a1ae1253869e4193c7ead209767696
https://doi.org/10.1007/978-1-0716-1716-8_7
https://doi.org/10.1007/978-1-0716-1716-8_7
Autor:
David, Witalka, Lisa J, Lapidus
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2376
Observation of protein folding on submillisecond time scales requires specialized ultra-rapid mixers coupled to optical or chemical probes. Here we describe the protocol for employing a microfabricated mixer with a mixing time of 8 μs coupled to a U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::090d861528e2efe1d62d561e26a64695
https://pubmed.ncbi.nlm.nih.gov/34845607
https://pubmed.ncbi.nlm.nih.gov/34845607
Autor:
Lisa J. Lapidus
Publikováno v:
The Biophysicist. 2:107-108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b74703d2362d0d4c5f13866262cd1cad
https://doi.org/10.35459/tbp.2021.000208
https://doi.org/10.35459/tbp.2021.000208