Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lisa J Funkhouser-Jones"'
Autor:
Jason A Metcalf, Lisa J Funkhouser-Jones, Kristen Brileya, Anna-Louise Reysenbach, Seth R Bordenstein
Publikováno v:
eLife, Vol 3 (2014)
Though horizontal gene transfer (HGT) is widespread, genes and taxa experience biased rates of transferability. Curiously, independent transmission of homologous DNA to archaea, bacteria, eukaryotes, and viruses is extremely rare and often defies eco
Externí odkaz:
https://doaj.org/article/f4ac21db84244dc482002d4a945ca9be
Autor:
Lisa J. Funkhouser-Jones, Rui Xu, Georgia Wilke, Yong Fu, Lawrence A. Schriefer, Heyde Makimaa, Rachel Rodgers, Elizabeth A. Kennedy, Kelli L. VanDussen, Thaddeus S. Stappenbeck, Megan T. Baldridge, L. David Sibley
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112680- (2023)
Summary: Cryptosporidiosis is a leading cause of life-threatening diarrhea in young children in resource-poor settings. To explore microbial influences on susceptibility, we screened 85 microbiota-associated metabolites for their effects on Cryptospo
Externí odkaz:
https://doaj.org/article/59e6a266f8ee48cab18b8af576086baf
Autor:
Kelli L. VanDussen, Lisa J. Funkhouser-Jones, Marianna E. Akey, Deborah A. Schaefer, Kevin Ackman, Michael W. Riggs, Thaddeus S. Stappenbeck, L. David Sibley
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT The protozoan parasite Cryptosporidium sp. is a leading cause of diarrheal disease in those with compromised or underdeveloped immune systems, particularly infants and toddlers in resource-poor localities. As an enteric pathogen, Cryptospori
Externí odkaz:
https://doaj.org/article/15ba3df73dfa42048c217995bef69455
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Cryptosporidium parvum and Cryptosporidium hominis have emerged as major enteric pathogens of infants in the developing world, in addition to their known importance in immunocompromised adults. Although there has been recent progress in iden
Externí odkaz:
https://doaj.org/article/a505818f45dc4bbba51c49d6a2f5bec1
Autor:
Lisa J. Funkhouser-Jones, Stephanie R. Sehnert, Paloma Martínez-Rodríguez, Raquel Toribio-Fernández, Miguel Pita, José L. Bella, Seth R. Bordenstein
Publikováno v:
PeerJ, Vol 3, p e1479 (2015)
Hybrid zones and the consequences of hybridization have contributed greatly to our understanding of evolutionary processes. Hybrid zones also provide valuable insight into the dynamics of symbiosis since each subspecies or species brings its unique m
Externí odkaz:
https://doaj.org/article/9921a6ad28d94047b5635794cd975f84
Autor:
Michael W. Riggs, Marianna E. Akey, Thaddeus S. Stappenbeck, Kevin Ackman, Deborah A. Schaefer, Kelli L. VanDussen, Lisa J. Funkhouser-Jones, L. David Sibley
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
mBio
mBio
Cryptosporidium sp. occupies a unique intracellular niche that exposes the parasite to both host cell contents and the intestinal lumen, including metabolites from the diet and produced by the microbiota. Both dietary and microbial products change ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e434caede46d4f55dc79be16b5d7f3
https://doi.org/10.1128/mbio.02582-20
https://doi.org/10.1128/mbio.02582-20
Autor:
Kevin Ackman, Marianna E. Akey, Lisa J. Funkhouser-Jones, Michael W. Riggs, L. David Sibley, Kelli L. VanDussen, Thaddeus S. Stappenbeck, Deborah A. Schaefer
The protozoan parasite Cryptosporidium is a leading cause of diarrheal disease in those with compromised or under-developed immune systems, particularly infants and toddlers in resource-poor localities. As an enteric pathogen, Cryptosporidium invades
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c009226d30a1b8c70f3098f275d2e48
https://doi.org/10.1101/2020.09.11.294462
https://doi.org/10.1101/2020.09.11.294462
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
mBio
mBio, Vol 11, Iss 2, p e00052-20 (2020)
mBio
mBio, Vol 11, Iss 2, p e00052-20 (2020)
Currently, nitazoxanide is the only FDA-approved treatment for cryptosporidiosis; unfortunately, it is ineffective in immunocompromised patients, has varied efficacy in immunocompetent individuals, and is not approved in infants under 1 year of age.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2ccd08c0205f90d42d6661917a32ef
https://journals.asm.org/doi/10.1128/mBio.00052-20
https://journals.asm.org/doi/10.1128/mBio.00052-20
Autor:
Kristen Monte, L. David Sibley, Devesha H. Kulkarni, Jiani N. Chai, Jisun Jung, Georgia Wilke, Alec Wehmeier, Chyi-Song Hsieh, Bernd H. Zinselmeyer, Aidan T. Miller, Jaeu Yi, Vivek Durai, Rafael S. Czepielewski, Shannon Young, Suellen Greco, Kenneth M. Murphy, Lindsey E. Fox, Lisa J. Funkhouser-Jones, Rodney D. Newberry, Emilie V. Russler-Germain
Publikováno v:
Immunity. 54:2547-2564.e7
Summary Cryptosporidium can cause severe diarrhea and morbidity, but many infections are asymptomatic. Here, we studied the immune response to a commensal strain of Cryptosporidium tyzzeri (Ct-STL) serendipitously discovered when conventional type 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdca12d9386207aece1d3cd6ecf7c476
https://doi.org/10.1016/j.immuni.2021.10.002
https://doi.org/10.1016/j.immuni.2021.10.002
Autor:
Seth R. Bordenstein, J. Dylan Shropshire, Daniel P. LePage, Jason A. Metcalf, Jessamyn I. Perlmutter, Emily M. Layton, John F. Beckmann, Jungmin On, Sarah R. Bordenstein, Lisa J. Funkhouser-Jones
Publikováno v:
Nature
The genus Wolbachia is an archetype of maternally inherited intracellular bacteria that infect the germline of numerous invertebrate species worldwide. They can selfishly alter arthropod sex ratios and reproductive strategies to increase the proporti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1f76bf43637aeda82f0b7501baec12
https://doi.org/10.1038/nature21391
https://doi.org/10.1038/nature21391