Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lisa Holsten"'
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102922- (2024)
Summary: As the number and complexity of transcriptomic datasets increase, there is a rising demand for accessible and user-friendly analysis tools. Here, we present hCoCena (horizontal construction of co-expression networks and analysis), a toolbox
Externí odkaz:
https://doaj.org/article/a43a47f052104a6785ba5234634eb9cd
Autor:
Jan Langkabel, Arik Horne, Lorenzo Bonaguro, Lisa Holsten, Tatiana Hesse, Alexej Knaus, Yannick Riedel, Matthias Becker, Kristian Händler, Tarek Elmzzahi, Kevin Bassler, Nico Reusch, Leon Harootoonovtch Yeghiazarian, Tal Pecht, Adem Saglam, Thomas Ulas, Anna C. Aschenbrenner, Franziska Kaiser, Caroline Kubaczka, Joachim L. Schultze, Hubert Schorle
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Synthetic embryo models have arisen as an approach to probe early development in vitro, facilitating the study of difficult to access stages. Here the authors present a simple system for generating embryo-like structures that resemble peri-implantati
Externí odkaz:
https://doaj.org/article/4777dcfcfbcb4d98ae83f5dc3f98bef3
Autor:
Kevin Baßler, Wataru Fujii, Theodore S. Kapellos, Erika Dudkin, Nico Reusch, Ari Horne, Benedikt Reiz, Malte D. Luecken, Collins Osei-Sarpong, Stefanie Warnat-Herresthal, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Allon Wagner, Patrick Günther, Carmen Pizarro, Tina Schreiber, Rainer Knoll, Lisa Holsten, Charlotte Kröger, Elena De Domenico, Matthias Becker, Kristian Händler, Christian T. Wohnhaas, Florian Baumgartner, Meike Köhler, Heidi Theis, Michael Kraut, Marc H. Wadsworth, Travis K. Hughes, Humberto J. Ferreira, Emily Hinkley, Ines H. Kaltheuner, Matthias Geyer, Christoph Thiele, Alex K. Shalek, Andreas Feißt, Daniel Thomas, Henning Dickten, Marc Beyer, Patrick Baum, Nir Yosef, Anna C. Aschenbrenner, Thomas Ulas, Jan Hasenauer, Fabian J. Theis, Dirk Skowasch, Joachim L. Schultze
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite its high prevalence, the cellular and molecular mechanisms of chronic obstructive pulmonary disease (COPD) are far from being understood. Here, we determine disease-related changes in cellular and molecular compositions within the alveolar sp
Externí odkaz:
https://doaj.org/article/e0f1f3d9372546f1a11d2fa5f19b33eb
Autor:
Anna C. Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S. Kapellos, Sarandia Doulou, Charlotte Kröger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D. Gemünd, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews, Lena Lenkeit, Niklas Bruse, Jelle Gerretsen, Jannik Gierlich, Matthias Becker, Kristian Händler, Michael Kraut, Heidi Theis, Simachew Mengiste, Elena De Domenico, Jonas Schulte-Schrepping, Lea Seep, Jan Raabe, Christoph Hoffmeister, Michael ToVinh, Verena Keitel, Gereon Rieke, Valentina Talevi, Dirk Skowasch, N. Ahmad Aziz, Peter Pickkers, Frank L. van de Veerdonk, Mihai G. Netea, Joachim L. Schultze, Matthijs Kox, Monique M. B. Breteler, Jacob Nattermann, Antonia Koutsoukou, Evangelos J. Giamarellos-Bourboulis, Thomas Ulas, German COVID-19 Omics Initiative (DeCOI)
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-25 (2021)
Abstract Background The SARS-CoV-2 pandemic is currently leading to increasing numbers of COVID-19 patients all over the world. Clinical presentations range from asymptomatic, mild respiratory tract infection, to severe cases with acute respiratory d
Externí odkaz:
https://doaj.org/article/00693afe88234ab7b97afcce182c0fb0
Autor:
Wataru Fujii, Theodore S. Kapellos, Kevin Baßler, Kristian Händler, Lisa Holsten, Rainer Knoll, Stefanie Warnat-Herresthal, Marie Oestreich, Emily R. Hinkley, Jan Hasenauer, Carmen Pizarro, Christoph Thiele, Anna C. Aschenbrenner, Thomas Ulas, Dirk Skowasch, Joachim L. Schultze
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Background Immune cells play a major role in the pathogenesis of COPD. Changes in the distribution and cellular functions of major immune cells, such as alveolar macrophages (AMs) and neutrophils are well known; however, their transcriptional reprogr
Externí odkaz:
https://doaj.org/article/ba9c72944c8e44c0884c83b5d5ae110e
Autor:
Thomas Ulas, Kevin Baßler, Dirk Skowasch, Lisa Holsten, Stefanie Warnat-Herresthal, Christoph Thiele, Jan Hasenauer, Theodore S. Kapellos, Carmen Pizarro, Joachim L. Schultze, Rainer Knoll, Anna C. Aschenbrenner, Wataru Fujii, Kristian Händler, Marie Oestreich, Emily R. Hinkley
Publikováno v:
ERJ Open Research
article-version (VoR) Version of Record
ERJ Open Research, Vol 7, Iss 3 (2021)
ERJ Open Research 7(3), 00915-2020 (2021). doi:10.1183/23120541.00915-2020
article-version (VoR) Version of Record
ERJ Open Research, Vol 7, Iss 3 (2021)
ERJ Open Research 7(3), 00915-2020 (2021). doi:10.1183/23120541.00915-2020
Background Immune cells play a major role in the pathogenesis of COPD. Changes in the distribution and cellular functions of major immune cells, such as alveolar macrophages (AMs) and neutrophils are well known; however, their transcriptional reprogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7c049420a3ebaffca5fc4ce0842822
https://doi.org/10.1183/23120541.00915-2020
https://doi.org/10.1183/23120541.00915-2020
Autor:
Marie Oestreich, Lisa Holsten, Shobhit Agrawal, Kilian Dahm, Philipp Koch, Han Jin, Matthias Becker, Thomas Ulas
Publikováno v:
Bioinformatics 38(20), 4727-4734 (2022). doi:10.1093/bioinformatics/btac589
Motivation Transcriptome-based gene co-expression analysis has become a standard procedure for structured and contextualized understanding and comparison of different conditions and phenotypes. Since large study designs with a broad variety of condit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6aef649b3c5667e5b43e9ff95868d7
https://pubmed.ncbi.nlm.nih.gov/36018233
https://pubmed.ncbi.nlm.nih.gov/36018233
Autor:
Jacob Nattermann, Benjamin Krämer, Nikolaos Antonakos, Kristian Händler, Martina van Uelft, Matthijs Kox, Rainer Knoll, Lorenzo Bonaguro, Monique M.B. Breteler, Jonas Schulte-Schrepping, Marie Oestreich, Melanie Nuesch-Germano, Kevin Baßler, Niklas Bruse, Matthias Becker, Valentina Talevi, Nikoletta Rovina, Mihai G. Netea, Michael ToVinh, Maria Mouktaroudi, Theodore S. Kapellos, Antonia Koutsoukou, Lea Seep, Thomas Ulas, Maria Saridaki, Elena De Domenico, Frank L. van de Veerdonk, Jan Raabe, Ioanna D. Gemünd, Konstantina Gkizeli, Michael Kraut, N. Ahmad Aziz, Joachim L. Schultze, Heidi Theis, Verena Keitel, German Covid Omics Initiative, Peter Pickkers, Nico Reusch, Miriam Herbert, Charlotte Kröger, Shobhit Agrawal, Gereon Rieke, Evangelos J. Giamarellos-Bourboulis, Lena Lenkeit, Jelle Gerretsen, Anna C. Aschenbrenner, Sarandia Doulou, Kilian Dahm, Arik Horne, Christoph Hoffmeister, Lisa Holsten, Simachew Mengiste, Anna Drews, Jannik Gierlich, Tal Pecht
SUMMARYThe SARS-CoV-2 pandemic is currently leading to increasing numbers of COVID-19 patients all over the world. Clinical presentations range from asymptomatic, mild respiratory tract infection, to severe cases with acute respiratory distress syndr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc331416788d981528fa1f1d2caadb5
https://doi.org/10.1101/2020.07.07.20148395
https://doi.org/10.1101/2020.07.07.20148395
