Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lisa Holmgren"'
Autor:
David P. Gearing, William E. Holmes, Jana Bodorova, Lisa Holmgren, Chenbei Chang, Samantha Chau, Elizabeth A. Woolf, Ali H. Brivanlou, Douglas A. Holtzman, Troy Chickering
Publikováno v:
Nature. 410:483-487
Bone morphogenetic proteins (BMPs), including the fly homologue Decapentaplegic (DPP), are important regulators of early vertebrate and invertebrate dorsal–ventral development1,2,3,4,5,6. An evolutionarily conserved BMP regulatory mechanism operate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09530d1c70460e6522ac94616a70a2fa
https://doi.org/10.1038/35068583
https://doi.org/10.1038/35068583
Autor:
Andrew W. Shyjan, Deborah L. Nagle, Jing Shao, Karen J. Moore, Barry J. Dussault, John J. Hunter, Elizabeth A. Woolf, John S. Smutko, Lisa Holmgren
Publikováno v:
Genomics. 54:116-123
We recently described a novel gene, melastatin, whose expression is inversely correlated with melanoma aggressiveness. Chromosomal localization of this gene places it on mouse chromosome 7 and in the 15q13–q14 region of the human genome. Although e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e98a301de95e251f2ed23d932860fd
https://doi.org/10.1006/geno.1998.5549
https://doi.org/10.1006/geno.1998.5549
Autor:
Deborah L. Nagle, Karen J. Moore, Barry J. Dussault, Peer Bork, Richard A. Spritz, Elizabeth A. Woolf, Geoffrey M. Duyk, Mohammad A. Karim, Donald J. Misumi, Charles M. Perou, Lisa Holmgren, Sonja H. McGrail, Raymond E. Boissy
Publikováno v:
Nature Genetics. 14:307-311
Chediak-Higashi syndrome (CHS) is a rare, autosomal recessive disorder characterized by hypopigmentation, severe immunologic deficiency with neutropenia and lack of natural killer (NK) cells, a bleeding tendency and neurologic abnormalities. Most pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5eae0445367f06fb94250751f945645
https://doi.org/10.1038/ng1196-307
https://doi.org/10.1038/ng1196-307
Identification and gene organization of three novel members of the IL-1 family on human chromosome 2
Autor:
Kevin R. Leiby, Troy Chickering, David P. Gearing, John S. Smutko, Hong Zhou, C.A. Comrack, G. Yu, Yang Pan, Lisa Holmgren, Samantha J. Busfield
Publikováno v:
Genomics. 66(2)
Members of the IL-1 family of cytokines are important in mediating inflammatory responses. The genes encoding IL-1alpha, IL-beta, and the IL-1 receptor antagonist (IL-1Ra) are clustered within 450 kb on human chromosome 2q. By searching the EST datab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b49f4d4499bd2287a46feaad7abceeb
https://pubmed.ncbi.nlm.nih.gov/10860666
https://pubmed.ncbi.nlm.nih.gov/10860666
Autor:
Chris Ebeling, Elizabeth A. Woolf, Dennis Huszar, Deborah L. Nagle, Sonja H. McGrail, Karen J. Moore, Barry J. Dussault, Paul Burn, Victoria Fairchild-Huntress, George A. Carlson, Peer Bork, Lisa DiRocco, Pei Ge, Jill Montagno, James Vitale, Lisa Holmgren, Linda Baldini, Julie Gilchrist, John Keilty
Publikováno v:
Nature. 398(6723)
Genetic studies have shown that mutations within the mahogany locus suppress the pleiotropic phenotypes, including obesity, of the agouti-lethal-yellow mutant. Here we identify the mahogany gene and its product; this study, to our knowledge, represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c81c69ddf177f97a5d9a88b173ef52c
https://pubmed.ncbi.nlm.nih.gov/10086355
https://pubmed.ncbi.nlm.nih.gov/10086355
Autor:
Liangtao Li, Karen J. Moore, Barry J. Dussault, Charles M. Perou, Monica J. Justice, Thomas H. Brody, Elizabeth A. Woolf, Lisa Holmgren, Cheryl A. Monroe, Robert J. Pryor, Sonja H. McGrail, Deborah L. Nagle, Donald J. Misumi, Jerry Kaplan, Geoffrey M. Duyk
Publikováno v:
Nature genetics. 13(3)
The beige mutation is a murine autosomal recessive disorder, resulting in hypopigmentation, bleeding and immune cell dysfunction. The gene defective in beige is thought to be a homologue of the gene for the human disorder Chediak-Higashi syndrome. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a96f6db3d94a316770cec8f1d1c5bd7
https://pubmed.ncbi.nlm.nih.gov/8673129
https://pubmed.ncbi.nlm.nih.gov/8673129
Identification and Characterization of the Mouse Obesity Gene tubby: A Member of a Novel Gene Family
Autor:
Ye Wu, Nathan D Lakey, Thomas Brody, Karen J. Moore, Janice A. Culpepper, George A. Carlson, Lisa Holmgren, Geoffrey D Alperin, John Lee, Patrick W. Kleyn, Jim Deeds, Elizabeth A. Woolf, Don J Misumi, Lucy R Berkemeier, Olga Tayber, Chris Ebeling, Linda Baldini, Olga Charlat, Jacqueline C. Pulido, Pei Shu, M.Alexandra Glücksmann-Kuis, Geoffrey M. Duyk, Steve G. Kovats, Brenda Kennedy, Fiona Hawkins, Hong Chen, Wei Fan
Publikováno v:
Cell. (2):281-290
The mutated gene responsible for the tubby obesity phenotype has been identified by positional cloning. A single base change within a splice donor site results in the incorrect retention of a single intron in the mature tub mRNA transcript. The conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c7ef0b80ca382729c3e1d5a185c1cd