Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lisa High Mitchell Smoot"'
Publikováno v:
BMC Neuroscience, Vol 18, Iss 1, Pp 1-20 (2017)
Abstract Background PDE4 cyclic nucleotide phosphodiesterases regulate 3′, 5′ cAMP abundance in the CNS and thereby regulate PKA activity and phosphorylation of CREB, which has been implicated in learning and memory, depression and other function
Externí odkaz:
https://doaj.org/article/cc4c65e396c04c169a96cf0d02d4e567
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5704, p 5704 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 16
International Journal of Molecular Sciences
Volume 21
Issue 16
PDE4 cyclic nucleotide phosphodiesterases reduce 3&prime
5&prime
cAMP levels in the CNS and thereby regulate PKA activity and the phosphorylation of CREB, fundamental to depression, cognition, and learning and memory. The PDE4 isoform PDE4D
5&prime
cAMP levels in the CNS and thereby regulate PKA activity and the phosphorylation of CREB, fundamental to depression, cognition, and learning and memory. The PDE4 isoform PDE4D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06a8000ae02be1053c4419dbdc35f5b
https://www.mdpi.com/1422-0067/21/16/5704
https://www.mdpi.com/1422-0067/21/16/5704
Publikováno v:
BMC Neuroscience, Vol 18, Iss 1, Pp 1-20 (2017)
BMC Neuroscience
BMC Neuroscience
Background: PDE4 cyclic nucleotide phosphodiesterases regulate 3′, 5′ cAMP abundance in the CNS and thereby regulate PKA activity and phosphorylation of CREB, which has been implicated in learning and memory, depression and other functions. The P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32008bcb38bfc066e28b5a3b830e256f
http://link.springer.com/article/10.1186/s12868-017-0396-6
http://link.springer.com/article/10.1186/s12868-017-0396-6
Autor:
Sérgio Veloso Brant Pinheiro, Mariana F Bizzi, Márta Korbonits, Giampaolo Trivellin, Graeme B. Bolger, Lisa High Mitchell Smoot, Mary-Ann Accavitti, Antônio Ribeiro-Oliveira
Publikováno v:
Endocrine-Related Cancer. 23:419-431
PDE4 cyclic nucleotide phosphodiesterases regulate cAMP abundance in cells and therefore regulate numerous processes, including cell growth and differentiation. The rat PDE4A5 isoform (human homolog PDE4A4) interacts with the AIP protein (also called
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68563328e77229496a2f98ab821985a4
https://doi.org/10.1530/erc-15-0205
https://doi.org/10.1530/erc-15-0205
Autor:
George Coricor, Graeme B. Bolger, Lisa High Mitchell Smoot, Yao Li, Mark T. Dransfield, James A. Lambert, Steven M. Rowe, Marina Mazur, Li Ping Tang, Carmel M. McNicholas, S. Vamsee Raju, Clifford A. Courville, Roopan F. Farris
Cigarette smoking causes acquired cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction and is associated with delayed mucociliary clearance and chronic bronchitis. Roflumilast is a clinically approved phosphodiesterase 4 inhibitor t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75da969166e73806cac6b5405837087
https://europepmc.org/articles/PMC4068936/
https://europepmc.org/articles/PMC4068936/
