Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lisa Gottschlich"'
Autor:
Emanuele Murgo, Elisabetta De Santis, Francesca Sansico, Valentina Melocchi, Tommaso Colangelo, Costanzo Padovano, Mattia Colucci, Annalucia Carbone, Beatrice Totti, Alireza Basti, Lisa Gottschlich, Angela Relogio, Nazzareno Capitanio, Fabrizio Bianchi, Gianluigi Mazzoccoli, Vincenzo Giambra
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-16 (2023)
Abstract Background T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy, characterized by restricted cellular subsets with asymmetrically enriched leukemia initiating cell (LIC) activity. Nonetheless, it is still unc
Externí odkaz:
https://doaj.org/article/0fc5f0bade7443538b5545e035167ada
Autor:
Lisa Gottschlich, Miriam Bortfeld-Miller, Christoph Gäbelein, Sebastian Dintner, Julia A Vorholt
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007294 (2018)
Two-component systems constitute phosphotransfer signaling pathways and enable adaptation to environmental changes, an essential feature for bacterial survival. The general stress response (GSR) in the plant-protecting alphaproteobacterium Sphingomon
Externí odkaz:
https://doaj.org/article/a21ced1735a54c28aed3273e55c67bcb
Autor:
Jan RH Hanauer, Lisa Gottschlich, Dennis Riehl, Tillmann Rusch, Vivian Koch, Katrin Friedrich, Stefan Hutzler, Steffen Prüfer, Thorsten Friedel, Kay-Martin Hanschmann, Robert C Münch, Christian Jost, Andreas Plückthun, Klaus Cichutek, Christian J Buchholz, Michael D Mühlebach
Publikováno v:
Molecular Therapy: Oncolytics, Vol 3, Iss C (2016)
To target oncolytic measles viruses (MV) to tumors, we exploit the binding specificity of designed ankyrin repeat proteins (DARPins). These DARPin-MVs have high tumor selectivity while maintaining excellent oncolytic potency. Stability, small size, a
Externí odkaz:
https://doaj.org/article/10476f0ec29d4a0b936f939cc2196b72
Autor:
Mathilde Cordellier, Verena Tams, Suda Parimala Ravindran, Lisa Gottschlich, Jennifer Lüneburg
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Gene expression patterns help to measure and characterize the effect of environmental perturbations at the cellular and organism-level. Complicating interpretation is the presence of uncharacterized or "hypothetical" gene functions for a large percen
Daphnia stressor database: Taking advantage of a decade of Daphnia ‘-omics’ data for gene annotation
Autor:
Suda Parimala Ravindran, Verena Tams, Mathilde Cordellier, Jennifer Lüneburg, Lisa Gottschlich
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Gene expression patterns help to measure and characterize the effect of environmental perturbations at the cellular and organism-level. Complicating interpretation is the presence of uncharacterized or “hypothetical” gene functions for a large pe
Autor:
Miriam Bortfeld-Miller, Christopher M. Field, Petra Geiser, Julia A. Vorholt, Lisa Gottschlich
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, 9 (1)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, 9 (1)
The general stress response (GSR) represents an important trait to survive in the environment by leading to multiple stress resistance. In alphaproteobacteria, the GSR is under the transcriptional control of the alternative sigma factor EcfG. Here we
Autor:
Anne Francez-Charlot, Sébastien Campagne, Frédéric H.-T. Allain, Miriam Bortfeld-Miller, Sebastian Dintner, Andreas Kaczmarczyk, Lisa Gottschlich, Maxence Thibault, Julia A. Vorholt
Publikováno v:
Structure (London, England : 1993). 24(8)
Two-component systems are major signal transduction pathways, which consist of histidine kinases and response regulators that communicate through phosphorylation. Here, we highlight a distinct class of single-domain response regulators containing the
Autor:
Robert C. Münch, Tillmann Rusch, Klaus Cichutek, Thorsten Friedel, Stefan Hutzler, Lisa Gottschlich, Katrin Friedrich, Jan R.H. Hanauer, Steffen Prüfer, Christian J. Buchholz, Christian Jost, Vivian Koch, Dennis Riehl, Michael D. Mühlebach, Kay-Martin Hanschmann, Andreas Plückthun
Publikováno v:
Molecular Therapy: Oncolytics, Vol 3, Iss C (2016)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
To target oncolytic measles viruses (MV) to tumors, we exploit the binding specificity of designed ankyrin repeat proteins (DARPins). These DARPin-MVs have high tumor selectivity while maintaining excellent oncolytic potency. Stability, small size, a
Publikováno v:
Metallomics : integrated biometal science. 5(5)
Copper plays essential roles in biology, but abnormal interactions are damaging. Reliable quantification of copper-protein interactions will underpin the molecular understanding of copper nutrition and toxicity. We have previously established two hig