Výsledky vyhledávání - "Lisa Goerens"

Akademický článek

Integration of the B-Cell Receptor Antigen Neurabin-I/SAMD14 Into an Antibody Format as New Therapeutic Approach for the Treatment of Primary CNS Lymphoma

Autor: Moritz Bewarder, Maximilian Kiefer, Clara Moelle, Lisa Goerens, Stephan Stilgenbauer, Konstantinos Christofyllakis, Dominic Kaddu-Mulindwa, Natalie Fadle, Evi Regitz, Frank Neumann, Markus Hoth, Klaus-Dieter Preuss, Michael Pfreundschuh, Lorenz Thurner

Publikováno v: Frontiers in Oncology, Vol 10 (2020)

Recently, neurabin-I and SAMD14 have been described as the autoantigenic target of approximately 66% of B-cell receptors (BCRs) of primary central nervous system lymphomas (PCNSL). Neurabin-I and SAMD14 share a highly homologous SAM domain that becom

Externí odkaz: https://doaj.org/article/18b55799ea4b4f80b3435573908e08d7

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The B-Cell Receptor Antigen ARS2 Can be Integrated into a BAR-Body Format to Treat Diffuse Large B-Cell Lymphomas in Xenograft Mouse Models

Autor: Michael Pfreundschuh, Evi Regitz, Moritz Bewarder, Lorenz Thurner, Matthias W. Laschke, Helene Will, Natalie Fadle, Lisa Goerens, Klaus Dieter Preuss, Frank Neumann, Stephan Stilgenbauer, Dominic Kaddu-Mulindwa, Michael D. Menger, Maximilian Kiefer, Christina Körbel

Publikováno v: Blood. 134:2860-2860

Chronic antigenic stimulation of the B-cell receptor (BCR) seems to play a critical role in the pathogenesis of B-cell lymphomas. We recently identified ARS2, LRPAP1 and Neurabin-I as the autoantigenic targets of the B-cell receptors of approximately

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f90507f49ad346c6b6c41c6c52b9050c
https://doi.org/10.1182/blood-2019-131434

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BAR-Bodies: B-Cell Receptor Antigens As the Targeting Moiety of Antibodies in Substitution for the Variable Region of Heavy and Light Chains

Autor: Konstantinos Christofyllakis, Maximilian Kiefer, Moritz Bewarder, Lisa Goerens, Dominic Kaddu-Mulindwa, Klaus Dieter Preuss, Evi Regitz, Maria Kemele, Natalie Fadle, Frank Neumann, Lorenz Thurner, Helene Will, Stephan Stilgenbauer

Publikováno v: Blood. 132:2940-2940

Background Chronic antigenic stimulation of the B-cell receptor (BCR) seems to play a critical role in the pathogenesis of B-cell lymphomas. We recently identified ARS2 and LRPAP1 as the autoantigenic targets of the B-cell receptors of approximately

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c97e3595a616db0af300d9138a5e1846
https://doi.org/10.1182/blood-2018-99-115348

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