Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Lisa Giulino-Roth"'
Autor:
Shene Chiou, Aysha H Al-Ani, Yi Pan, Komal M Patel, Isabella Y Kong, Lachlan W Whitehead, Amanda Light, Samuel N Young, Marilou Barrios, Callum Sargeant, Pradeep Rajasekhar, Leah Zhu, Anne Hempel, Ann Lin, James A Rickard, Cathrine Hall, Pradnya Gangatirkar, Raymond KH Yip, Wayne Cawthorne, Annette V Jacobsen, Christopher R Horne, Katherine R Martin, Lisa J Ioannidis, Diana S Hansen, Jessica Day, Ian P Wicks, Charity Law, Matthew E Ritchie, Rory Bowden, Joanne M Hildebrand, Lorraine A O’Reilly, John Silke, Lisa Giulino-Roth, Ellen Tsui, Kelly L Rogers, Edwin D Hawkins, Britt Christensen, James M Murphy, André L Samson
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 7, Pp 1717-1749 (2024)
Abstract Necroptosis is a lytic form of regulated cell death reported to contribute to inflammatory diseases of the gut, skin and lung, as well as ischemic-reperfusion injuries of the kidney, heart and brain. However, precise identification of the ce
Externí odkaz:
https://doaj.org/article/3261c59629e24716b5f237cbc3d2531c
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1011939 (2024)
Epstein-Barr virus (EBV) persistently infects 95% of adults worldwide and is associated with multiple human lymphomas that express characteristic EBV latency programs used by the virus to navigate the B-cell compartment. Upon primary infection, the E
Externí odkaz:
https://doaj.org/article/26731686f3c145fda023abbea69b282f
Publikováno v:
eJHaem, Vol 4, Iss 4, Pp 912-920 (2023)
Abstract Pediatric non‐Hodgkin lymphoma includes over 30 histologies (many with subtypes), with approximately 800 cases per year in the US, compared to >60,000 cases of adult NHL annually. Improvements in survival in pediatric and adolescent mature
Externí odkaz:
https://doaj.org/article/7d5ff98091504603b95b733003cf5798
Autor:
Isabella Y. Kong, Lisa Giulino-Roth
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Epstein-Barr virus (EBV) contributes to the development of a significant subset of human lymphomas. As a herpes virus, EBV can transition between a lytic state which is required to establish infection and a latent state where a limited number of vira
Externí odkaz:
https://doaj.org/article/3743b331b74a4e7a9992d691f6d995d8
Autor:
Graham P. Collins, Toby A. Eyre, Debora Schmitz-Rohmer, William Townsend, Rakesh Popat, Lisa Giulino-Roth, Paul A. Fields, Fatime Krasniqi, Carole Soussain, Anastasios Stathis, Nebojsa Andjelkovic, David Cunningham, Danijela Mandic, Sinisa Radulovic, Ivan Tijanic, Netanel A. Horowitz, Sabira Kurtovic, Elisabeth Schorb, Christian Schmidt, Saša Dimitrijević, Martin Dreyling
Publikováno v:
HemaSphere, Vol 5, Iss 11, p e656 (2021)
Bimiralisib is an orally bioavailable pan-phosphatidylinositol 3-kinase and mammalian target of rapamycin inhibitor which has shown activity against lymphoma in preclinical models. This phase I/II study evaluated the response rate to bimiralisib at 2
Externí odkaz:
https://doaj.org/article/8e18548fde2a404c9bbf77be27391d61
Autor:
Yaya Chu, Sanghoon Lee, Tishi Shah, Changhong Yin, Matthew Barth, Rodney R. Miles, Janet Ayello, Erin Morris, Lauren Harrison, Carmella Van de Ven, Paul Galardy, Stanton C. Goldman, Megan S. Lim, Michelle Hermiston, Linda M. McAllister-Lucas, Lisa Giulino-Roth, Sherrie L. Perkins, Mitchell S. Cairo
Publikováno v:
OncoImmunology, Vol 8, Iss 1 (2019)
Pediatric and adult patients with recurrent/refractory Burkitt lymphoma (BL) continue to have poor outcomes, emphasizing the need for newer therapeutic agents. Bruton’s tyrosine kinase (BTK) is activated following B-cell receptor stimulation and in
Externí odkaz:
https://doaj.org/article/2466fcc030424707a6dd1a4e9329ef32
Autor:
David Egg, Charlotte Schwab, Annemarie Gabrysch, Peter D. Arkwright, Edmund Cheesman, Lisa Giulino-Roth, Olaf Neth, Scott Snapper, Satoshi Okada, Michel Moutschen, Philippe Delvenne, Ann-Christin Pecher, Daniel Wolff, Yae-Jean Kim, Suranjith Seneviratne, Kyoung-Mee Kim, Ji-Man Kang, Samar Ojaimi, Catriona McLean, Klaus Warnatz, Maximilian Seidl, Bodo Grimbacher
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background: Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) is a negative immune regulator on the surface of T cells. In humans, heterozygous germline mutations in CTLA4 can cause an immune dysregulation syndrome. The phenotype comprises a broad
Externí odkaz:
https://doaj.org/article/27f24119d6174f2ba0ac828f55c874a1
Publikováno v:
Journal of the National Comprehensive Cancer Network. 21:323-330
Primary mediastinal B-cell lymphoma (PMBCL) is a rare but aggressive mature B-cell lymphoma that arises from thymic B cells and most commonly affects adolescents and young adults. PMBCL is now recognized by the WHO as a distinct entity from diffuse l
Autor:
Francesco Maura, Bachisio Ziccheddu, Jenny Z. Xiang, Bhavneet Bhinder, Joel Rosiene, Federico Abascal, Kylee H. Maclachlan, Kenneth Wha Eng, Manik Uppal, Feng He, Wei Zhang, Qi Gao, Venkata D. Yellapantula, Vicenta Trujillo-Alonso, Sunita I. Park, Matthew J. Oberley, Elizabeth Ruckdeschel, Megan S. Lim, Gerald B. Wertheim, Matthew J. Barth, Terzah M. Horton, Andriy Derkach, Alexandra E. Kovach, Christopher J. Forlenza, Yanming Zhang, Ola Landgren, Craig H. Moskowitz, Ethel Cesarman, Marcin Imielinski, Olivier Elemento, Mikhail Roshal, Lisa Giulino-Roth
Publikováno v:
Blood Cancer Discovery. 4:208-227
The rarity of malignant Hodgkin and Reed Sternberg (HRS) cells in classic Hodgkin lymphoma (cHL) limits the ability to study the genomics of cHL. To circumvent this, our group has previously optimized fluorescence-activated cell sorting to purify HRS
Autor:
Lisa Giulino-Roth, Mikhail Roshal, Olivier Elemento, Marcin Imielinski, Ethel Cesarman, Craig H. Moskowitz, Ola Landgren, Yanming Zhang, Christopher J. Forlenza, Alexandra E. Kovach, Andriy Derkach, Terzah M. Horton, Matthew J. Barth, Gerald B. Wertheim, Megan S. Lim, Elizabeth Ruckdeschel, Matthew J. Oberley, Sunita I. Park, Vicenta Trujillo-Alonso, Venkata D. Yellapantula, Qi Gao, Wei Zhang, Feng He, Manik Uppal, Kenneth Wha Eng, Kylee H. Maclachlan, Federico Abascal, Joel Rosiene, Bhavneet Bhinder, Jenny Z. Xiang, Bachisio Ziccheddu, Francesco Maura
R code of our analysis clock like mutational signatures in Hodgkin lymphoma WGS and WES.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae1ecef2c571b23aacfe9bfcc819d93
https://doi.org/10.1158/2643-3230.22725557
https://doi.org/10.1158/2643-3230.22725557