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Autor:
Mani Annamalai, Christina Amatya, John D. Glawe, Scott E. Stimpson, Clayton E. Mathews, Christopher G. Kevil, Robert L. Whitener, Jian-Wei Li, Shuyao Zhang, Sarah Knapp, Arif Yurdagul, Shuai Yuan, DongTao Fu, Vadim M. Pliner, Ilian A. Radichev, Jing Chen, Alexei Y. Savinov, Lisa Gallo Knight
Publikováno v:
The Journal of Immunology. 199:3991-4000
Type 1 diabetes (T1D) has a strong genetic component. The insulin dependent diabetes (Idd)22 locus was identified in crosses of T1D-susceptible NOD mice with the strongly T1D-resistant ALR strain. The NODcALR-(D8Mit293-D8Mit137)/Mx (NOD-Idd22) recomb