Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lisa G. Clifton"'
Autor:
Stephen A. Stimpson, Todd W. Shearer, Fritz Kramer, Ying Shen, Marc K. Hellerstein, Chelsea King, Po-yin Anne Wong, Mahalakshmi Shankaran, Alan J. Russell, Philip Stewart Turnbull, William J. Evans, Lisa G. Clifton, Scott M. Turner
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 310:E405-E417
Biomarkers of muscle protein synthesis rate could provide early data demonstrating anabolic efficacy for treating muscle-wasting conditions. Androgenic therapies have been shown to increase muscle mass primarily by increasing the rate of muscle prote
Publikováno v:
Journal of Molecular Histology
We have identified integrin beta 6 (Itgb6) as a transcript highly enriched in skeletal muscle. This finding is unexpected because Itgb6 is typically associated with epithelial expression domains in normal tissue. Further we find that ITGB6 protein ex
Autor:
Roger H. Brown, Carie L. Kimbrough, Jessica R Durrant, David Bailey, Catherine A. Faber, Chandikumar S. Elangbam, W. Wallace Harrington, Nikki Slocum, Tula Milliken, Lisa G. Clifton, Holly L. Jordan, Joanna C. Barton, Lawrence Yoon, Neal F. Cariello
Publikováno v:
Experimental and Toxicologic Pathology. 65:549-557
Drug-induced weight loss in humans has been associated with undesirable side effects not present in weight loss from lifestyle interventions (caloric restriction or exercise). To investigate the mechanistic differences of weight loss by drug-induced
Autor:
Stephen A. Stimpson, Lisa G. Clifton, Richard V. Clark, Marc K. Hellerstein, Katja Remlinger, Todd W. Shearer, Scott M. Turner, Michael S. Leonard, James C. Poole, William J. Evans
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Background We recently validated in cross-sectional studies a new method to determine total body creatine pool size and skeletal muscle mass based on D3-creatine dilution from an oral dose and detection of urinary creatinine enrichment by isotope rat
Autor:
Marc K. Hellerstein, Scott M. Turner, James C. Poole, Michael S. Leonard, Richard V. Clark, Lisa G. Clifton, Stephen A. Stimpson, Katja Remlinger, William J. Evans, Todd W. Shearer
Publikováno v:
The FASEB Journal. 27
We recently described a new method to determine total body creatine pool size and skeletal muscle mass based on dilution of an oral dose of D3-creatine in urinary creatinine. Enrichment of D3- crea...
Autor:
Stephen A. Stimpson, Laura Hagerty, Katja Remlinger, Greg M. Waitt, Marc K. Hellerstein, James C. Poole, Scott M. Turner, Lisa G. Clifton, Hussein Mohammed, William J. Evans, Todd W. Shearer
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 112(11)
There is currently no direct, facile method to determine total-body skeletal muscle mass for the diagnosis and treatment of skeletal muscle wasting conditions such as sarcopenia, cachexia, and disuse. We tested in rats the hypothesis that the enrichm
Autor:
Ying Qian, James A. Triantafillou, Judi A. McNulty, Bajin Han, Jay C. Strum, Baichun Yang, Stephen A. Stimpson, Kevin Carrick, Lisa G. Clifton, Robert S. Geske, Kathleen K. Brown, Lihong Chen, Greg L. Pahel
Publikováno v:
Biochemical and biophysical research communications. 341(1)
The current study examined the relationship between skeletal muscle levels of adiponectin and parameters of insulin sensitivity. A high fat/sucrose diet (HFD) for 20 weeks resulted in significant increases in body weight, serum insulin, triglycerides
Autor:
Baichun Yang, Kevin Carrick, Lisa G. Clifton, Judi A. McNulty, Peiyuan Lin, Deborah A. Winegar, Stephen A. Stimpson, Jay C. Strum, Greg L. Pahel
Publikováno v:
Biochemical and biophysical research communications. 334(1)
We investigated the effect of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists on serum vascular endothelial growth factor (VEGF) in diet-induced insulin resistant SD rats and ZDF rats. SD rats fed a high fat/sucrose diet showed
Autor:
Stephen A. Stimpson, Baichun Yang, W. Wallace Harrington, Lisa G. Clifton, Angela Grimes, Lihong Chen, Thomas W. Balon, Zibin Chen, Jane G Binz, Judi A. McNulty, Kathleen K. Brown, Jay C. Strum
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 312(2)
Peroxisome proliferator-activated receptor-gamma (PPARgamma) agonists have been shown to have significant therapeutic benefits such as desirable glycemic control in type 2 diabetic patients; however, these agents may cause fluid retention in suscepti
Autor:
Baichun, Yang, Kathleen K, Brown, Lihong, Chen, Kevin M, Carrick, Lisa G, Clifton, Judi A, McNulty, Deborah A, Winegar, Jay C, Strum, Stephen A, Stimpson, Gregory L, Pahel
Publikováno v:
BMC Pharmacology
Background PPARγ agonists ameliorate insulin resistance and dyslipidemia in type 2 diabetic patients. Adiponectin possesses insulin sensitizing properties, and predicts insulin sensitivity of both glucose and lipid metabolism. In diet-induced insuli