Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Lisa Fortmueller"'
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Akademický článek
Endurance Training Provokes Arrhythmogenic Right Ventricular Cardiomyopathy Phenotype in Heterozygous Desmoglein-2 Mutants: Alleviation by Preload Reduction
Autor: Larissa Fabritz, Lisa Fortmueller, Katja Gehmlich, Sebastian Kant, Marcel Kemper, Dana Kucerova, Fahima Syeda, Cornelius Faber, Rudolf E. Leube, Paulus Kirchhof, Claudia A. Krusche
Publikováno v: Biomedicines, Vol 12, Iss 5, p 985 (2024)
Desmoglein-2 mutations are detected in 5–10% of patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). Endurance training accelerates the development of the ARVC phenotype, leading to earlier arrhythmic events. Homozygous Dsg2 mutant
Externí odkaz: https://doaj.org/article/5a5105ab2727484b917460f3f967de2c
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128 Desmosomal instability increases atrial arrhythmia susceptibility after endurance training
Autor: Lisa Fortmueller, Georgios V. Gkoutos, Monika Stoll, Victor Cardoso Roth, Andrew P. Holmes, Susanne Lutz, Clara Apicella, Priyanka Menon, Paulus Kirchhof, S. Wells, Fahima Syeda, Thomas Wright, E Vloumidi, S N Kabir, Claire Hepburn, Davor Pavlovic, Larissa Fabritz, Aaron Isaacs, Ting Yu
Publikováno v: Basic Science.
Background Endurance training has recently been associated with increased risk of atrial fibrillation (AF). In patients with desmosomal dysfunction, exercise can promote disease progression and ventricular arrhythmias. We studied the effect of desmos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00d59a212da8801be0dbbc8ecb887387
https://doi.org/10.1136/heartjnl-2018-bcs.127
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PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression
Autor: Ilaria Piccini, Peter C. Kahr, H. H. Scheld, Sander Verheule, Ulrich Schotten, Paulus Kirchhof, Lisa Fortmueller, Nigel A. Brown, Heinrich Rotering, Sandra Laakmann, Larissa Fabritz, Sven Kaese, Ismail Vokshi
Publikováno v: Circulation: Cardiovascular Genetics; Vol 4
Circulation : Cardiovascular Genetics, 4(2), 123-U84. LIPPINCOTT WILLIAMS & WILKINS
Background— Intergenic variations on chromosome 4q25, close to the PITX2 transcription factor gene, are associated with atrial fibrillation (AF). We therefore tested whether adult hearts express PITX2 and whether variation in expression affects car
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1fdf55b0c8c1441bc3523627c96a069
https://doi.org/10.1161/CIRCGENETICS.110.958058
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5
First report on an inotropic peptide activating tetrodotoxin-sensitive, 'neuronal' sodium currents in the heart
Autor: Petra Ehling, Nir Nesher, Wilhelm Schmitz, Larissa Fabritz, Eliahu Zlotkin, Jan Klimas, Tatayana Kanyshkova, Paulus Kirchhof, Birgit Stallmeyer, Sigrid Nikol, Frank U. Müller, Thomas Budde, Uwe Kirchhefer, Eric Schulze-Bahr, Jan S. Schulte, Tzachy Tal, Lisa Fortmueller
Publikováno v: Circulation. Heart failure. 8(1)
Background— New therapeutic approaches to improve cardiac contractility without severe risk would improve the management of acute heart failure. Increasing systolic sodium influx can increase cardiac contractility, but most sodium channel activator
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef612032b6e18578cb989fe154dcf829
https://pubmed.ncbi.nlm.nih.gov/25424392
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