Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Lisa F. Lincz"'
Autor:
Anoop K. Enjeti, Natasha Walker, Oliver Fahey, Elizabeth Johnston, Hannah Legge‐Wilkinson, Nateika Ramsurrun, Jonathan Sillar, Lisa F. Lincz, Andrew Ziolkowski, David Mossman
Publikováno v:
eJHaem, Vol 5, Iss 5, Pp 957-963 (2024)
Abstract Introduction Variants of uncertain significance (VUS) are commonly reported in cancer with the widespread adoption of diagnostic massive parallel sequencing. The rate of reclassification of VUS in patients with haematological malignancy is n
Externí odkaz:
https://doaj.org/article/24a802e1f0234d89943545abb89af369
Autor:
Anjana Silva, Fiona E. Scorgie, Lisa F. Lincz, Kalana Maduwage, Sisira Siribaddana, Geoffrey K. Isbister
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundVenom-induced consumption coagulopathy (VICC) is an important clinical consequence of Russell’s viper (Daboia russelii) envenoming. There is limited evidence for antivenom effectiveness in resolving VICC. We aimed to compare the recovery
Externí odkaz:
https://doaj.org/article/9b240ceab5064d869bee70b44aff43ba
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 1 (2022)
The importance of Ca2+ signaling, and particularly Ca2+ channels, in key events of cancer cell function such as proliferation, metastasis, autophagy and angiogenesis, has recently begun to be appreciated. Of particular note are two-pore channels (TPC
Externí odkaz:
https://doaj.org/article/8280ab16866b46a7814051cb21461546
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 563 (2022)
Acute myeloid leukaemia (AML) is a heterogeneous disease with one of the worst survival rates of all cancers. The bone marrow microenvironment is increasingly being recognised as an important mediator of AML chemoresistance and relapse, supporting le
Externí odkaz:
https://doaj.org/article/0ead9fc79b24406baec9fd3d61dd6e68
Autor:
Madeleine Birgersson, Mengna Chi, Chrissy Miller, Joshua S. Brzozowski, Jeffrey Brown, Lachlan Schofield, Olivia G. Taylor, Elizabeth A. Pearsall, Jasmine Hewitt, Craig Gedye, Lisa F. Lincz, Kathryn A. Skelding
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Brain and Acute Leukemia, Cytoplasmic (BAALC) is a protein that controls leukemia cell proliferation, differentiation, and survival and is overexpressed in several cancer types. The gene is located in the chromosomal region 8q22.3, an area commonly a
Externí odkaz:
https://doaj.org/article/1d22781a642948e899f2a3475d30bcf2
Autor:
Lisa F. Lincz, Lisa-Maree Mudge, Fiona E. Scorgie, Jennette A. Sakoff, Christopher S. Hamilton, Michael Seldon
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 10, Pp 1131-1137 (2008)
Telomerase activity is primarily determined by transcriptional regulation of the catalytic subunit, human telomerase reverse transcriptase (hTERT). Several mRNA splice variants for hTERT have been identified, but it is not clear if telomerase activit
Externí odkaz:
https://doaj.org/article/0c551a8447a54ab0979e4eac157829dc
Autor:
Lisa F. Lincz, Rick F. Thorne, Estelle Sontag, Hubert Hondermarck, Charles E. de Bock, Abdulrzag F. Ahmed
Publikováno v:
Biochemical and Biophysical Research Communications. 514:625-631
Fat1 cadherin is broadly expressed throughout the nervous system and has been implicated in neuronal differentiation. Here we examined the functional contribution of FAT1 during neuronal differentiation of the Ntera2 cell line model. FAT1 expression
Publikováno v:
Research and Practice in Thrombosis and Haemostasis
Background Venom‐induced consumption coagulopathy is a common consequence of snake envenoming that can lead to life‐threatening hemorrhage, and is associated with microangiopathic hemolytic anemia (MAHA), acute kidney injury and thrombocytopenia.
Publikováno v:
Journal of Cancer Metastasis and Treatment. 2020
Autor:
Lisa F. Lincz, Matthew D. Jose, Ritam Prasad, Andrew G Smith, Nicole Lioufas, Rahul P. Patel, Madhur D. Shastri, Tracey J. Batt
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 31(2)
Lowmolecular weight heparins are used during haemodialysis for thromboprophylaxis of the dialysis circuit, with plasma antifactor-Xa (anti-Xa) activity used as a surrogate measure for effective anticoagulation. However, this pharmacokinetic parameter