Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lisa Ellerby"'
Autor:
Pankaj Kapahi, Kenneth Wilson, Sudipta Bar, Eric Dammer, Brian Hodge, Enrique Carrera, Tyler Hilsabeck, Joanna Bons, George Brownridge, Jennifer Beck, Jacob Rose, Melia Granath-Panelo, Christopher Nelson, Alexandra Afenjar, Geetanjali Chawla, Rachel Brem, Philippe Campeau, Hugo Bellen, Birgit Schilling, Nicholas Seyfried, Lisa Ellerby
Dietary restriction (DR) delays aging and neurodegeneration, but the mechanisms behind this remain to be elucidated. We identified genetic polymorphisms in mustard (mtd), the fly homolog of Oxidation resistance 1 (OXR1), which influenced lifespan and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80eec93e5c225b9b0a2b04a86d4cea63
https://doi.org/10.21203/rs.3.rs-1455343/v1
https://doi.org/10.21203/rs.3.rs-1455343/v1
Autor:
Jordi Creus-Muncunill, Daniele Mattei, Joanna Bons, Angie V. Ramirez-Jimenez, B. Wade Hamilton, Chuhyon Corwin, Sarah Chowdhury, Birgit Schilling, Lisa Ellerby, Michelle E. Ehrlich
BACKGROUNDHuntington’s disease (HD) is a fatal neurodegenerative disorder caused by an expansion of the CAG trinucleotide repeat in the huntingtin gene. Immune activation is abundant in the striatum of HD patients. Detection of active microglia at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce1fd1e242772557d07b5d5971fea0d
https://doi.org/10.1101/2022.02.18.480944
https://doi.org/10.1101/2022.02.18.480944
Autor:
Kenneth Wilson, Sudipta Bar, Eric Dammer, Birgit Schilling, Nicholas Seyfried, Hugo Bellen, Lisa Ellerby, Pankaj Kapahi
Publikováno v:
Innovation in Aging. 6:730-730
Dietary restriction (DR) delays aging and neurodegeneration, but the mechanisms behind this remain unclear. We reared over 150 fully sequenced fly strains from the Drosophila Genetic Reference Panel under ad libitum feeding or diet-restricted conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb880457aa69152bd3bdb1907af67e4d
https://doi.org/10.1093/geroni/igac059.2661
https://doi.org/10.1093/geroni/igac059.2661
Autor:
Eric J, Bennett, Tom, Shaler, Mirella, Gonzalez-Zulueta, Howard F, Schulman, Atsushi, Iwata, Brigit E, Riley, Jennifer A, Johnston, Mirella, Bucci, Noboyuki, Nukina, Lisa, Ellerby, Ron R, Kopito
Publikováno v:
Rinsho shinkeigaku = Clinical neurology. 46(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79865532640b7276c8bc1c10fe8a648b
https://pubmed.ncbi.nlm.nih.gov/17432184
https://pubmed.ncbi.nlm.nih.gov/17432184
Autor:
Deepinder, Kaur, Ferda, Yantiri, Subramanian, Rajagopalan, Jyothi, Kumar, Jun Qin, Mo, Rapee, Boonplueang, Veena, Viswanath, Russell, Jacobs, Lichuan, Yang, M Flint, Beal, Dino, DiMonte, Irene, Volitaskis, Lisa, Ellerby, Robert A, Cherny, Ashley I, Bush, Julie K, Andersen
Publikováno v:
Neuron. 37(6)
Studies on postmortem brains from Parkinson's patients reveal elevated iron in the substantia nigra (SN). Selective cell death in this brain region is associated with oxidative stress, which may be exacerbated by the presence of excess iron. Whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f80e2e936b205c2a136c39079007a84
https://pubmed.ncbi.nlm.nih.gov/12670416
https://pubmed.ncbi.nlm.nih.gov/12670416