Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Lisa E. Wagar"'
Autor:
Mahina Tabassum Mitul, Jenna M. Kastenschmidt, Suhas Sureshchandra, Zachary W. Wagoner, Andrew M. Sorn, David R. Mcllwain, Jenny E. Hernandez-Davies, Aarti Jain, Rafael de Assis, Douglas Trask, D. Huw Davies, Lisa E. Wagar
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Sex-based differences in immune cell composition and function can contribute to distinct adaptive immune responses. Prior work has quantified these differences in peripheral blood, but little is known about sex differences within human lymphoid tissu
Externí odkaz:
https://doaj.org/article/57db89dbdea9471c90ce9b0acccdf68a
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-14 (2018)
Abstract There are fundamental differences between humans and the animals we typically use to study the immune system. We have learned much from genetically manipulated and inbred animal models, but instances in which these findings have been success
Externí odkaz:
https://doaj.org/article/12080ad3f917400ca9fd44b9f26bc628
Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children
Autor:
Lisa E. Wagar, Christopher R. Bolen, Natalia Sigal, Cesar J. Lopez Angel, Leying Guan, Beth D. Kirkpatrick, Rashidul Haque, Robert J. Tibshirani, Julie Parsonnet, William A. Petri, Mark M. Davis
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
During the first 5 years of life, children are especially vulnerable to infection-related morbidity and mortality. Conversely, the Hygiene Hypothesis suggests that a lack of exposure to infectious agents early in life could explain the increasing inc
Externí odkaz:
https://doaj.org/article/7eda52eb9d10465cbf66c63ae683fec5
Autor:
Qian Yin, Wei Luo, Vamsee Mallajosyula, Yang Bo, Jing Guo, Jinghang Xie, Meng Sun, Rohit Verma, Chunfeng Li, Christian M. Constantz, Lisa E. Wagar, Jing Li, Elsa Sola, Neha Gupta, Chunlin Wang, Oliver Kask, Xin Chen, Xue Yuan, Nicholas C. Wu, Jianghong Rao, Yueh-hsiu Chien, Jianjun Cheng, Bali Pulendran, Mark M. Davis
Publikováno v:
Nature materials, vol 22, iss 3
The ideal vaccine against viruses such as influenza and SARS-CoV-2 must provide a robust, durable and broad immune protection against multiple viral variants. However, antibody responses to current vaccines often lack robust cross-reactivity. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9e5a2894f2a6f1915187af816bf497
https://escholarship.org/uc/item/7gc737gh
https://escholarship.org/uc/item/7gc737gh
Autor:
Jenna Kastenschmidt, Suhas Sureshchandra, Aarti Jain, Jenny E. Hernandez-Davies, Rafael de Assis, Zachary Wagoner, Andrew M. Sorn, Mahina Tabassum Mitul, Aviv I. Benchorin, Elizabeth Levendosky, Gurpreet Ahuja, Qiu Zhong, Douglas Trask, Jacob Boeckmann, Rie Nakajima, Algimantas Jasinskas, Naresha Saligrama, D. Huw Davies, Lisa E. Wagar
Publikováno v:
SSRN Electronic Journal.
Autor:
Meng Sun, Rohit Verma, Jing Li, Neha Gupta, Yang Bo, Oliver Kask, Christian McCrory Constantz, Jing Guo, Wei Luo, Jianghong Rao, Yueh-hsiu Chien, Lisa E. Wagar, Jianjun Cheng, Jinghang Xie, Bali Pulendran, Elsa Solà, Mark M. Davis, Venkata Vamsee Aditya Mallajosyula, Qian Yin
Fully effective vaccines for viruses such as Influenza and SARS-CoV-2 must elicit a diverse repertoire of antibodies against multiple drifted virus strains. However, how to achieve a diverse response has no general solution except to combine multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8703c4e07772dd5fa93ee7c2eb3be5ef
https://doi.org/10.21203/rs.3.rs-936346/v1
https://doi.org/10.21203/rs.3.rs-936346/v1
Autor:
Hamish W King, Robson Capasso, Mark M. Davis, Arwa Kathiria, Lars M. Steinmetz, Zohar Shipony, Kristen L. Wells, Nara Orban, Louisa K. James, William J. Greenleaf, Caleb A. Lareau, Lisa E. Wagar
Publikováno v:
Sci Immunol
The germinal center (GC) response is critical for both effective adaptive immunity and establishing peripheral tolerance by limiting autoreactive B cells. Dysfunction in these processes can lead to defective immune responses to infection or contribut
Autor:
Michael S. Khodadoust, Binbin Chen, Lisa E. Wagar, Brian Sworder, Joshua E. Elias, Mark M. Davis, Niclas Olsson, Yagmur Muftuoglu, Chih Long Liu, Ash A. Alizadeh, Ethan Fast, Ronald Levy, Russ B. Altman, Maximilian Diehn
Publikováno v:
Nature biotechnology, vol 37, iss 11
Nat Biotechnol
Nat Biotechnol
Accurate prediction of antigen presentation by human leukocyte antigen (HLA) class II molecules would be valuable for vaccine development and cancer immunotherapies. Current computational methods trained on in vitro binding data are limited by insuff
Autor:
William J. Greenleaf, Robson Capasso, Zohar Shipony, Lars M. Steinmetz, Louisa K. James, Caleb A. Lareau, Hamish W King, Nara Orban, Arwa Kathiria, Kristen L. Wells, Lisa E. Wagar, Mark M. Davis
The germinal center (GC) response is critical for both effective adaptive immunity and establishing peripheral tolerance by limiting auto-reactive B cells. Dysfunction in these processes can lead to defects in immune response to pathogens or contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::141a6a510aa5c0cbc2384a630bfe432e
https://doi.org/10.1101/2021.03.16.435578
https://doi.org/10.1101/2021.03.16.435578
Autor:
Mario Cortese, Gregory B. Hammer, Sean N. Tucker, Katharina Röltgen, Anne I. Sperling, Christian McCrory Constantz, Scott D. Boyd, Mark M. Davis, Krishna M. Roskin, Julia Z. Adamska, D. Huw Davies, Neha Gupta, Philip L. Felgner, Iram N. Ahmad, Aarti Jain, Ben S. Wendel, Kelly M. Blaine, Fan Yang, Michael Lyons, Ameen A. Salahudeen, Lisa K. Blum, Kara D. Meister, Emery G. Dora, Lauren P. Jatt, Vamsee Mallajosyula, Katherine J. L. Jackson, William H. Robinson, Calvin J. Kuo, Peter S. Kim, Lisa E. Wagar
Publikováno v:
Nature medicine, vol 27, iss 1
Nat Med
Nature Medicine
Nat Med
Nature Medicine
Most of what we know about adaptive immunity has come from inbred mouse studies, using methods that are often difficult or impossible to confirm in humans. In addition, vaccine responses in mice are often poorly predictive of responses to those same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749ec4370f6ba55f6caa1ab0658a21f6
https://escholarship.org/uc/item/3hs0m6t8
https://escholarship.org/uc/item/3hs0m6t8