Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Lisa E. Kalynchuk"'
Autor:
Carla L. Sánchez-Lafuente, Jenessa N. Johnston, Brady S. Reive, Kaylene K. A. Scheil, Ciara S. Halvorson, Mariana Jimenez, Darian Colpitts, Lisa E. Kalynchuk, Hector J. Caruncho
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
IntroductionTreatment with the synaptic plasticity protein reelin has rapid antidepressant-like effects in adult corticosterone (CORT)-induced depressed rats, whether administered repeatedly or acutely. However, these effects remain unexplored in the
Externí odkaz:
https://doaj.org/article/1ef3153f87a14230a1fa9afb275308b4
Autor:
B.S. Reive, Jenessa N. Johnston, Carla L. Sánchez-Lafuente, Lucy Zhang, Aland Chang, Jasmine Zhang, Josh Allen, Raquel Romay-Tallon, Lisa E. Kalynchuk, Hector J. Caruncho
Publikováno v:
Chronic Stress, Vol 7 (2023)
Reelin, an extracellular matrix protein with putative antidepressant-like properties, becomes dysregulated by chronic stress. Improvement in cognitive dysfunction and depression-like behavior induced by chronic stress has been reported with both intr
Externí odkaz:
https://doaj.org/article/ce231d6724ee44a1a19e8e73a36f702b
Autor:
Jenessa N. Johnston, Lisa Ridgway, Sarah Cary-Barnard, Josh Allen, Carla L. Sanchez-Lafuente, Brady Reive, Lisa E. Kalynchuk, Hector J. Caruncho
Publikováno v:
Research Involvement and Engagement, Vol 7, Iss 1, Pp 1-11 (2021)
Plain English summary This paper presents a roadmap for patient-oriented research in mental health in Canada. At the level of laboratory science, the direct involvement of patients and their collaboration with researchers on experimental development
Externí odkaz:
https://doaj.org/article/24a1bd684a314223b91ccdd274734ab4
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3213 (2022)
A healthy diet has been highly associated with a decreased risk for mental health problems such as major depression. Evidence from human studies shows that diet can influence mood but there is a poor understanding of the molecular mechanisms behind t
Externí odkaz:
https://doaj.org/article/c8a82c3d437445f59606912907f236cb
Autor:
Jenessa N. Johnston, Jonathan S. Thacker, Charissa Desjardins, Brian D. Kulyk, Raquel Romay-Tallon, Lisa E. Kalynchuk, Hector J. Caruncho
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Depression is the leading cause of disability worldwide, which necessitates novel therapeutics and biomarkers to approach treatment of this neuropsychiatric disorder. To assess potential mechanisms underlying the fast-acting antidepressant actions of
Externí odkaz:
https://doaj.org/article/023e24ab05a9424e967366c1bb3732c0
Publikováno v:
Cells, Vol 11, Iss 4, p 748 (2022)
Methyl-CpG-binding protein 2 (MeCP2) is a transcriptional regulator that is highly abundant in the brain. It binds to methylated genomic DNA to regulate a range of physiological functions implicated in neuronal development and adult synaptic plastici
Externí odkaz:
https://doaj.org/article/cb2dafe30df447d1a32a79b419e581ed
Autor:
Raquel Romay-Tallon, Tania Rivera-Baltanas, Josh Allen, Jose M. Olivares, Lisa E. Kalynchuk, Hector J. Caruncho
Publikováno v:
Biomarker Research, Vol 5, Iss 1, Pp 1-8 (2017)
Abstract Background The pattern of serotonin transporter clustering on the plasma membrane of lymphocytes extracted from human whole blood samples has been identified as a putative biomarker of therapeutic efficacy in major depression. Here we evalua
Externí odkaz:
https://doaj.org/article/488d9c79fec34f6e94d4c955d38d59be
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/7df32ef6bbd14238a444e76ccea5ca6b
Autor:
Hector J. Caruncho, Tania Rivera-Baltanas, Raquel Romay-Tallon, Lisa E. Kalynchuk, Jose M. Olivares
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
There is an utmost necessity of developing novel biomarkers of depression that result in a more efficacious use of current antidepressant drugs. The present report reviews and discusses a recent series of experiments that focused on analysis of membr
Externí odkaz:
https://doaj.org/article/1c9f0adbdf364d7ba890e24dd5f38fd9
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Human and animal studies suggest an intriguing relationship between the immune system and the development of depression. Some peripherally produced cytokines, such as TNF-α, can cross the blood brain barrier and result in activation of brain microgl
Externí odkaz:
https://doaj.org/article/49a7d4f955ca44fa892e7b6c0ac0167e