Výsledky vyhledávání - "Lisa E, Goehler"

In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression

Autor: Lisa E. Goehler, Michael Maes, Ewa Obuchowicz, Joanna Brzeszcz, Marta Kubera

Publikováno v: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 35:744-759

Recently, the inflammatory and neurodegenerative (IND) hypothesis of depression was formulated (Maes et al., 2009), i.e. the neurodegeneration and reduced neurogenesis that characterize depression are caused by inflammation, cell-mediated immune acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ef21654ad9b12b15a3434d4f683ff8
https://doi.org/10.1016/j.pnpbp.2010.08.026

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Ascending caudal medullary catecholamine pathways drive sickness-induced deficits in exploratory behavior: Brain substrates for fatigue?

Autor: Lisa E. Goehler, Ronald P.A. Gaykema

Publikováno v: Brain, Behavior, and Immunity. 25:443-460

Immune challenges can lead to marked behavioral changes, including fatigue, reduced social interest, anorexia, and somnolence, but the precise neuronal mechanisms that underlie sickness behavior remain elusive. Part of the neurocircuitry influencing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3590f283a7b40c0b33aa70fd421ff3fe
https://doi.org/10.1016/j.bbi.2010.11.005

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How does immune challenge inhibit ingestion of palatable food? Evidence that systemic lipopolysaccharide treatment modulates key nodal points of feeding neurocircuitry

Autor: Su Mi Park, Lisa E. Goehler, Ronald P.A. Gaykema

Publikováno v: Brain, Behavior, and Immunity. 22:1160-1172

Immune challenge induces behavioral changes including reduced ingestion of palatable food. Multiple pathways likely contribute to this effect, including viscerosensory pathways controlling hypothalamic feeding circuits or by influence on "reward" cir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ab2bd8345fdba8827caf255181aba6
https://doi.org/10.1016/j.bbi.2008.05.001

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Campylobacter jejuni infection increases anxiety-like behavior in the holeboard: Possible anatomical substrates for viscerosensory modulation of exploratory behavior

Autor: Noel Opitz, Su Mi Park, Ronald P.A. Gaykema, Lisa E. Goehler, Mark Lyte

Publikováno v: Brain, Behavior, and Immunity. 22:354-366

The presence of certain bacteria in the gastrointestinal tract influences behavior and brain function. For example, challenge with live Campylobacter jejuni (C. jejuni), a common food-born pathogen, reduces exploration of open arms of the plus maze,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b526137d1508e57cfb3986e35d16e15
https://doi.org/10.1016/j.bbi.2007.08.009

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Stress, Inflammation and Pain: A Potential Role for Monocytes in Fibromyalgia-related Symptom Severity

Autor: Ann Gill, Taylor, Tamara G, Fischer-White, Joel G, Anderson, Katharine E, Adelstein, Maheswari, Murugesan, Janet E, Lewis, Michael M, Scott, Ronald P A, Gaykema, Lisa E, Goehler

Publikováno v: Stress and health : journal of the International Society for the Investigation of Stress. 32(5)

The possibility that immunological changes might contribute to symptom severity in fibromyalgia (FM) prompted this proof-of-concept study to determine whether differences in monocyte subpopulations might be present in persons with FM compared with he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fde432d46c5f87ccc6498e1836675e90
https://pubmed.ncbi.nlm.nih.gov/27925450

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Interleukin-1 induces c-Fos immunoreactivity in primary afferent neurons of the vagus nerve

Autor: Lisa E. Goehler, Linda R. Watkins, Ronald P.A. Gaykema, Sayamwong E. Hammack, Steven F. Maier

Publikováno v: Brain Research. 804:306-310

Peripheral administration of bacterial endotoxin, an immune stimulant, induces evidence of activation in vagal primary afferent neurons. To determine whether interleukin-1beta (IL-1beta) is part of the molecular pathway leading to this activation, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55e3f9d76818d45f07c61c14461bab1
https://doi.org/10.1016/s0006-8993(98)00685-4

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Thermogenic and corticosterone responses to intravenous cytokines (IL-1β and TNF-α) are attenuated by subdiaphragmatic vagotomy

Autor: B.A Schwartz, Linda R. Watkins, Steven F. Maier, Lisa E. Goehler, David Martin, Molly McGorry, Monika Fleshner

Publikováno v: Journal of Neuroimmunology. 86:134-141

The brain orchestrates changes in behavior and physiology as a consequence of peripheral immune activation and infection. These changes require that the brain receives signals from the periphery that an immunological challenge has occurred. Previous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a986c6e33dc81337fcd423a03d39da70
https://doi.org/10.1016/s0165-5728(98)00026-5

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The Role of the Vagus Nerve in Cytokine-to-Brain Communication

Autor: Lisa E. Goehler, Linda R. Watkins, Steven F. Maier, Monika Fleshner

Publikováno v: Annals of the New York Academy of Sciences. 840:289-300

Peripheral interleukin-1 beta (IL-beta) and inflammatory stimuli that induce the synthesis and release of IL-1 beta produce a variety of central nervous system responses. Most proposals designed to explain how peripheral IL-1 beta influences the CNS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d9b0e2ed04fb145506de47c43ce7d5
https://doi.org/10.1111/j.1749-6632.1998.tb09569.x

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