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Recombinant Mitochondrial Transcription Factor A with N-terminal Mitochondrial Transduction Domain Increases Respiration and Mitochondrial Gene Expression in G11778A Leber's Hereditary Optic Neuropathy Cybrid Cells

Autor: Lisa Dunahm, Ravindar R. Thomas, Shilpa Iyer, James Bennett, Caitlin K. Quigley, Francisco R. Portell

Publikováno v: Nature Precedings.

Diseases involving mitochondrial defects usually manifest themselves in high-energy, post-mitotic tissues such as brain, retina, skeletal and cardiac muscle and frequently cause deficiencies in mitochondrial bioenergetics. We have developed a scalabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84983cb0e6e6a461ba8fe3d35d33bb4d
https://doi.org/10.1038/npre.2008.2084.1

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