Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Lisa Detering"'
Autor:
Lu Su, Kellie S. Dalby, Hannah Luehmann, Sussana A. Elkassih, Sangho Cho, Xun He, Lisa Detering, Yen-Nan Lin, Nari Kang, Dennis A. Moore, Richard Laforest, Guorong Sun, Yongjian Liu, Karen L. Wooley
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 4, Pp 1660-1670 (2023)
To expand the single-dose duration over which noninvasive clinical and preclinical cancer imaging can be conducted with high sensitivity, and well-defined spatial and temporal resolutions, a facile strategy to prepare ultrasmall nanoparticulate X-ray
Externí odkaz:
https://doaj.org/article/e7261962bbb84ae9b003fc1dcfe14759
Autor:
Yongfeng Zhao PhD, Bo Pang PhD, Lisa Detering MS, Hannah Luehmann MS, Miaoxin Yang PhD, Kvar Black PhD, Deborah Sultan BS, Younan Xia PhD, Yongjian Liu PhD
Publikováno v:
Molecular Imaging, Vol 17 (2018)
Purpose: Melanoma is a lethal skin cancer with unmet clinical needs for targeted imaging and therapy. Nanoscale materials conjugated with targeting components have shown great potential to improve tumor delivery efficiency while minimizing undesirabl
Externí odkaz:
https://doaj.org/article/4100276a9c0040a59c9d398e3a710b69
Autor:
Xiaohui Zhang, Lisa Detering, Deborah Sultan, Gyu Seong Heo, Hannah Luehmann, Sara Taylor, Ankur Choksi, Joshua B. Rubin, Yongjian Liu
Publikováno v:
ACS Applied Bio Materials. 5:235-242
Autor:
Hannah Pang, Abhishek Sethi, Ankur Choksi, Yongjian Liu, Dezhuang Ye, Hong Chen, Oren J. Becher, David D. Limbrick, Christopher Pham Pacia, Hannah Luehmann, Joshua B. Rubin, Yimei Yue, Lihua Yang, Gyu Seong Heo, Xiaohui Zhang, Yuan-Chuan Tai, Lisa Detering, Deborah Sultan
Publikováno v:
ACS Appl Nano Mater
Diffuse intrinsic pontine glioma (DIPG) is an invasive pediatric brainstem malignancy exclusively in children without effective treatment due to the often-intact blood-brain tumor barrier (BBTB), an impediment to the delivery of therapeutics. Herein,
Autor:
Xiaohui, Zhang, Lisa, Detering, Deborah, Sultan, Gyu Seong, Heo, Hannah, Luehmann, Sara, Taylor, Ankur, Choksi, Joshua B, Rubin, Yongjian, Liu
Publikováno v:
ACS applied bio materials. 5(1)
Glioblastoma multiforme (GBM) is the most prevalent and aggressive primary malignant brain cancer in adults, and it carries a poor prognosis. Despite the current multimodality treatment, including surgery, radiation, and chemotherapy, the overall sur
Autor:
Kian-Huat Lim, Gyu Seong Heo, James Stec, Shunqiang Li, Lisa Detering, Tina Primeau, Yongjian Liu, A. Craig Lockhart, Yi Shan Lee, Richard Laforest, Hannah Luehmann
Publikováno v:
Molecular Pharmaceutics. 16:3996-4006
Folate receptor α (FRα) is a well-studied tumor biomarker highly expressed in many epithelial tumors such as breast, ovarian, and lung cancers. Mirvetuximab soravtansine (IMGN853) is the antibody-drug conjugate of FRα-binding humanized monoclonal
Autor:
Eric D. Pressly, Alaina J. McGrath, Yongjian Liu, Craig J. Hawker, Hannah Luehmann, Dana R. Abendschein, Lisa Detering, Annie Nguyen, Robert J. Gropler, Monica Shokeen, Pamela K. Woodard, Mohamed A. Zayed, Deborah Sultan, Susannah A Grathwohl
Publikováno v:
ACS Appl Mater Interfaces
ACS applied materials & interfaces, vol 11, iss 17
ACS applied materials & interfaces, vol 11, iss 17
Nanoparticles have been assessed in preclinical models of atherosclerosis for detection of plaque complexity and treatment. However, their successful clinical translation has been hampered by less than satisfactory plaque detection, and lack of a gen
Autor:
Kory J. Lavine, Florian Leuschner, Geetika Bajpai, Lisa Detering, Christophe Combadière, Robert J. Gropler, Benjamin Kopecky, Deborah Sultan, Steven L. Brody, Daniel Kreisel, Monica Ou, Gyu Seong Heo, Guoshuai Feng, Yi Su, Xiaohui Zhang, Yongjian Liu, Hannah Luehmann
Publikováno v:
Circulation Research. 124:881-890
Rationale: Paradigm shifting studies have revealed that the heart contains functionally diverse populations of macrophages derived from distinct embryonic and adult hematopoietic progenitors. Under steady-state conditions, the heart is largely popula
Autor:
Xiuli Zhang, Hannah Luehmann, Deborah Sultan, Lisa Detering, Yongjian Liu, Lin Li, Farrokh Dehdashti, Lanlan Lou, Suellen Greco, Gyu Seong Heo, Xiaohui Zhang, Marianna B. Ruzinova, Patrick M. Grierson, Richard Laforest, Kian-Huat Lim
Publikováno v:
Radiol Imaging Cancer
Pancreatic ductal adenocarcinoma (PDAC) is a deadly malignancy with dire prognosis due to aggressive biology, lack of effective tools for diagnosis at an early stage, and limited treatment options. Detection of PDAC using conventional radiographic im
Autor:
Osamu Baba, Li-Hao Huang, Deborah Sultan, Gwendalyn J. Randolph, Andrew Elvington, Yongjian Liu, Martyna Szpakowska, Lisa Detering, Hannah Luehmann, Andy Chevigné, Gyu Seong Heo, Xiaohui Zhang
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 41(2)
Objective: vMIP-II (viral macrophage inflammatory protein 2)/vCCL2 (viral chemotactic cytokine ligand 2) binds to multiple chemokine receptors, and vMIP-II-based positron emission tomography tracer ( 64 Cu-DOTA-vMIP-II: vMIP-II tracer) accumulates at