Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lisa D. Urness"'
Autor:
Rolen M. Quadros, Hiromi Miura, Donald W. Harms, Hisako Akatsuka, Takehito Sato, Tomomi Aida, Ronald Redder, Guy P. Richardson, Yutaka Inagaki, Daisuke Sakai, Shannon M. Buckley, Parthasarathy Seshacharyulu, Surinder K. Batra, Mark A. Behlke, Sarah A. Zeiner, Ashley M. Jacobi, Yayoi Izu, Wallace B. Thoreson, Lisa D. Urness, Suzanne L. Mansour, Masato Ohtsuka, Channabasavaiah B. Gurumurthy
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Background Conditional knockout mice and transgenic mice expressing recombinases, reporters, and inducible transcriptional activators are key for many genetic studies and comprise over 90% of mouse models created. Conditional knockout mice a
Externí odkaz:
https://doaj.org/article/cc09dd43b09b4403b9ad7415943adf1e
Autor:
Joshua D. Wythe, Michael J. Jurynec, Lisa D. Urness, Christopher A. Jones, M. Khaled Sabeh, Andreas A. Werdich, Mariko Sato, H. Joseph Yost, David J. Grunwald, Calum A. MacRae, Dean Y. Li
Publikováno v:
Disease Models & Mechanisms, Vol 4, Iss 5, Pp 607-621 (2011)
SUMMARY The vertebrate heart is one of the first organs to form, and its early function and morphogenesis are crucial for continued embryonic development. Here we analyze the effects of loss of Heart adaptor protein 1 (Hadp1), which we show is requir
Externí odkaz:
https://doaj.org/article/70b4d00401de4ceda2f37e882d663460
Autor:
Chaoying Li, Suzanne L. Mansour, Channabasavaiah B. Gurumurthy, Lisa D. Urness, Donald W. Harms, Xiaofen Wang, Rolen M. Quadros
Publikováno v:
Development
Pan-otic CRE drivers enable gene regulation throughout the otic placode lineage, comprising the inner ear epithelium and neurons. However, intersection of extra-otic gene-of-interest expression with the CRE lineage can compromise viability and impede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9c3274914e40cb02183400b8f40436
https://europepmc.org/articles/PMC7358128/
https://europepmc.org/articles/PMC7358128/
Autor:
Channabasavaiah B. Gurumurthy, Rolen M. Quadros, Suzanne L. Mansour, Donald W. Harms, Chaoying Li, Xiaofen Wang, Lisa D. Urness
Pan-otic CRE drivers enable gene regulation throughout the otic placode lineage, comprising the inner ear epithelium and neurons. However, intersection of extra-otic gene-of-interest expression with the CRE lineage can compromise viability and impede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::596dd777ce330cf97b005f8845da5c46
https://doi.org/10.1101/2020.05.26.118026
https://doi.org/10.1101/2020.05.26.118026
Autor:
Yutaka Inagaki, Suzanne L. Mansour, Ronald Redder, Parthasarathy Seshacharyulu, Guy P. Richardson, Daisuke Sakai, Mark A. Behlke, Masato Ohtsuka, Hisako Akatsuka, Rolen M. Quadros, Channabasavaiah B. Gurumurthy, Lisa D. Urness, Tomomi Aida, Donald W. Harms, Takehito Sato, Wallace B. Thoreson, Shannon M. Buckley, Yayoi Izu, Sarah A. Zeiner, Hiromi Miura, Ashley M. Jacobi, Surinder K. Batra
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-15 (2017)
Genome Biology
Genome Biology
Background Conditional knockout mice and transgenic mice expressing recombinases, reporters, and inducible transcriptional activators are key for many genetic studies and comprise over 90% of mouse models created. Conditional knockout mice are genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18d729e2d7fc752e6730f9c4382957e
http://link.springer.com/article/10.1186/s13059-017-1220-4
http://link.springer.com/article/10.1186/s13059-017-1220-4
Autor:
Ree Lu, C. Albert Noyes, Suzanne L. Mansour, Lisa D. Urness, Edgar Gutierrez-Magana, Nathan Shumway, Xiaofen Wang, Huy Doan
Morphogenesis of the inner ear epithelium requires coordinated deployment of several signaling pathways and disruptions cause abnormalities of hearing and/or balance. The FGFR2b ligands, FGF3 and FGF10, are expressed throughout otic development and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bd8dbd09e8acfc6fbecfed2329915f
https://doi.org/10.1101/430876
https://doi.org/10.1101/430876
Autor:
Suzanne L. Mansour, Lisa D. Urness, Tomomi Aida, Rolen M. Quadros, Sarah A. Zeiner, Ronald Redder, Mark A. Behlke, Ashley M. Jacobi, Donald W. Harms, Channabasavaiah B. Gurumurthy, Hiromi Miura, Guy P. Richardson, Masato Ohtsuka
CRISPR/Cas9 technology efficiently produces short insertions or deletions (indels) and can insert short exogenous sequences at Cas9 cut sites. However, targeting long inserts is still a major technical challenge. To overcome this challenge, we develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367e876b87f8a6af17870ba652af6668
https://doi.org/10.1101/069963
https://doi.org/10.1101/069963
Autor:
Dean Y. Li, Mariko Sato, Lisa D. Urness, Christopher A. Jones, M. Khaled Sabeh, Joshua D. Wythe, Calum A. MacRae, H. Joseph Yost, David Grunwald, Michael J. Jurynec, Andreas A. Werdich
Publikováno v:
Disease Models & Mechanisms, Vol 4, Iss 5, Pp 607-621 (2011)
Disease Models & Mechanisms
Disease Models & Mechanisms
SUMMARYThe vertebrate heart is one of the first organs to form, and its early function and morphogenesis are crucial for continued embryonic development. Here we analyze the effects of loss of Heart adaptor protein 1 (Hadp1), which we show is require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76624a46a22e75399b600a419e9fc61
http://dmm.biologists.org/content/4/5/607
http://dmm.biologists.org/content/4/5/607
Publikováno v:
Developmental Biology. 340:595-604
The inner ear epithelium, with its complex array of sensory, non-sensory, and neuronal cell types necessary for hearing and balance, is derived from a thickened patch of head ectoderm called the otic placode. Mouse embryos lacking both Fgf3 and Fgf10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5714764f25ce9145cc2ce4bc7cdcafa6
https://doi.org/10.1016/j.ydbio.2010.02.016
https://doi.org/10.1016/j.ydbio.2010.02.016
Publikováno v:
Developmental Dynamics. 238:358-366
Fibroblast growth factors play important roles in inner ear development. Previous studies showed that mouse Fgf16 is expressed asymmetrically during the otic cup and vesicle stages of development, suggesting roles in regulating or responding to anter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b878342766075a458e149156aa70d3
https://doi.org/10.1002/dvdy.21681
https://doi.org/10.1002/dvdy.21681