Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lisa D. Cervia"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 263-271 (2018)
The nuclear envelope is a physiological barrier to electrogene transfer. To understand different mechanisms of the nuclear entry for electrotransfected plasmid DNA (pDNA), the current study investigated how manipulation of the mechanisms could affect
Externí odkaz:
https://doaj.org/article/733d56f0bfa740a6943fad7ef44a885a
Autor:
William C. Hahn, Francisca Vazquez, James M. McFarland, David E. Root, Steven A. Carr, Meagan E. Olive, Namrata D. Udeshi, Federica Piccioni, John Michael Krill-Burger, Joshua M. Dempster, Mariya Kazachkova, Nolan R. Bick, Alfredo Gonzalez, Nancy Dumont, Brian H. Shim, Sydney M. Moyer, Naomi Li, Lisa Leung, Linh He, Benjamin Gaeta, Ashir A. Borah, Tsukasa Shibue, Lisa D. Cervia
Systematic identification of signaling pathways required for the fitness of cancer cells will facilitate the development of new cancer therapies. We used gene essentiality measurements in 1,086 cancer cell lines to identify selective coessentiality m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fc76a0c251e4642a82d828d0e369b2
https://doi.org/10.1158/2159-8290.c.6549921.v1
https://doi.org/10.1158/2159-8290.c.6549921.v1
Autor:
William C. Hahn, Francisca Vazquez, James M. McFarland, David E. Root, Steven A. Carr, Meagan E. Olive, Namrata D. Udeshi, Federica Piccioni, John Michael Krill-Burger, Joshua M. Dempster, Mariya Kazachkova, Nolan R. Bick, Alfredo Gonzalez, Nancy Dumont, Brian H. Shim, Sydney M. Moyer, Naomi Li, Lisa Leung, Linh He, Benjamin Gaeta, Ashir A. Borah, Tsukasa Shibue, Lisa D. Cervia
Supplementary Figure S1 shows the strategy and result of co-essentiality module identificationfrom the DepMap CRISPR screen dataset and further characterization of the BIRC6 module. Supplementary Figure S2 shows the viability effect of BIRC6 depletio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879d88026d2d97772a09ffcc4c904be6
https://doi.org/10.1158/2159-8290.22542432.v1
https://doi.org/10.1158/2159-8290.22542432.v1
Autor:
David G. Kirsch, Jimena Giudice, Stephano S. Mello, Krista Pipho, Brian P. Rubin, Alexander J. Lazar, Jay S. Wunder, Irene L. Andrulis, Samuel Singer, Tomoyo Okada, Andrew Seto, Nalan Gokgoz, Kouros Owzar, Dadong Zhang, Xiaodi Qin, Fan Yuan, Lisa D. Cervia, Omar Lopez, Nerissa T. Williams, Yan Ma, Lixia Luo, Timothy J. Robinson, Eric Xu, Mohit Sachdeva, Jianguo Huang
Table S1. Primers for real time qPCR. Table S2. p53 mutation status in sarcoma patients. Table S3. The list of lncRNAs that are significantly differentially expressed in lung metastases compared to paired KP primary tumors. Table S4. The list of prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ece028771431fbe454bca1b04995b29
https://doi.org/10.1158/1541-7786.22516723.v1
https://doi.org/10.1158/1541-7786.22516723.v1
Autor:
David G. Kirsch, Jimena Giudice, Stephano S. Mello, Krista Pipho, Brian P. Rubin, Alexander J. Lazar, Jay S. Wunder, Irene L. Andrulis, Samuel Singer, Tomoyo Okada, Andrew Seto, Nalan Gokgoz, Kouros Owzar, Dadong Zhang, Xiaodi Qin, Fan Yuan, Lisa D. Cervia, Omar Lopez, Nerissa T. Williams, Yan Ma, Lixia Luo, Timothy J. Robinson, Eric Xu, Mohit Sachdeva, Jianguo Huang
Supplementary Figure S1. An example of measurements on a staining tissue section. Supplementary Figure S2. The Scripts used for blind analysis of the lung colonization study. Supplementary Figure S3. Example of measurements on a whole lung section. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5abe83a1a4c3c9528593184d97d09dcc
https://doi.org/10.1158/1541-7786.22516726.v1
https://doi.org/10.1158/1541-7786.22516726.v1
Autor:
Lisa D Cervia, Tsukasa Shibue, Benjamin Gaeta, Ashir A Borah, Lisa Leung, Naomi Li, Nancy Dumont, Alfredo Gonzalez, Nolan Bick, Mariya Kazachkova, Joshua M Dempster, John M Krill-Burger, Federica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
Publikováno v:
Cancer Research. 82:P3-09
Targeting of mutated oncogenes has led to the identification of new targeted therapies. However, druggable oncogenes do not occur in most cancers. Systematic identification of signaling pathways required for the fitness of cancer cells will facilitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::836287162264eb635377806800a676c7
https://doi.org/10.1158/1538-7445.sabcs21-p3-09-01
https://doi.org/10.1158/1538-7445.sabcs21-p3-09-01
Autor:
Lisa D. Cervia, Tsukasa Shibue, Ashir A. Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M. Moyer, Brian H. Shim, Nancy Dumont, Alfredo Gonzalez, Nolan R. Bick, Mariya Kazachkova, Joshua M. Dempster, John Michael Krill-Burger, Federica Piccioni, Namrata D. Udeshi, Meagan E. Olive, Steven A. Carr, David E. Root, James M. McFarland, Francisca Vazquez, William C. Hahn
Publikováno v:
Cancer discovery.
Systematic identification of signaling pathways required for the fitness of cancer cells will facilitate the development of new cancer therapies. We used gene essentiality measurements in 1,086 cancer cell lines to identify selective coessentiality m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0d97ef1950d305b2eebc76a84aa30d
https://pubmed.ncbi.nlm.nih.gov/36576405
https://pubmed.ncbi.nlm.nih.gov/36576405
Autor:
Lisa D. Cervia, Nerissa Williams, Tomoyo Okada, Jianguo Huang, Timothy J. Robinson, Alexander J. Lazar, Nalan Gokgoz, Yan Ma, Samuel Singer, Krista Pipho, Jay S. Wunder, Stephano S. Mello, David G. Kirsch, Andrew Seto, Xiaodi Qin, Kouros Owzar, Omar M. Lopez, Mohit Sachdeva, Eric S. Xu, Lixia Luo, Fan Yuan, Jimena Giudice, Irene L. Andrulis, Dadong Zhang, Brian P. Rubin
Publikováno v:
Mol Cancer Res
Soft-tissue sarcomas (STS) are rare malignancies showing lineage differentiation toward diverse mesenchymal tissues. Half of all high-grade STSs develop lung metastasis with a median survival of 15 months. Here, we used a genetically engineered mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6005d9c55f889e635869dd44d18ef949
https://doi.org/10.1158/1541-7786.mcr-19-1170
https://doi.org/10.1158/1541-7786.mcr-19-1170
Autor:
Lisa D. Cervia, Tsukasa Shibue, Benjamin Gaeta, Ashir A. Borah, Lisa Leung, Naomi Li, Nancy Dumont, Alfredo Gonzalez, Nolan Bick, Mariya Kazachkova, Joshua M. Dempster, John M. Krill-Burger, Federica Piccioni, Namrata D. Udeshi, Meagan E. Olive, Steven A. Carr, David E. Root, James M. McFarland, Francisca Vazquez, William C. Hahn
Publikováno v:
Cancer Research. 82:73-73
Targeting of mutated oncogenes has led to the identification of new targeted therapies. However, druggable oncogenes do not occur in most cancers. Systematic identification of signaling pathways required for the fitness of cancer cells will facilitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::697e2301039bd0bcdbc1a4ccfe4c3523
https://doi.org/10.1158/1538-7445.am2022-73
https://doi.org/10.1158/1538-7445.am2022-73
Autor:
Fan Yuan, Liangli Wang, Jing Ji, Lisa D. Cervia, Adrian Pickar-Oliver, Charles A. Gersbach, Chun-Chi Chang, Mao Mao, Paloma B. Liton
Publikováno v:
Adv Biosyst
Cell engineering relies heavily on viral vectors for the delivery of molecular cargo into cells due to their superior efficiency compared to nonviral ones. However, viruses are immunogenic and expensive to manufacture, and have limited delivery capac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52385a0c5b25d69c41b8ddd2a3276c4d
https://pubmed.ncbi.nlm.nih.gov/33179869
https://pubmed.ncbi.nlm.nih.gov/33179869