Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Lisa D Wilsbacher"'
Autor:
Jun Zou, Diana Tran, Mai Baalbaki, Ling Fung Tang, Annie Poon, Angelo Pelonero, Erron W Titus, Christiana Yuan, Chenxu Shi, Shruthi Patchava, Elizabeth Halper, Jasmine Garg, Irina Movsesyan, Chaoying Yin, Roland Wu, Lisa D Wilsbacher, Jiandong Liu, Ronald L Hager, Shaun R Coughlin, Martin Jinek, Clive R Pullinger, John P Kane, Daniel O Hart, Pui-Yan Kwok, Rahul C Deo
Publikováno v:
eLife, Vol 4 (2015)
Truncating mutations in the giant sarcomeric protein Titin result in dilated cardiomyopathy and skeletal myopathy. The most severely affected dilated cardiomyopathy patients harbor Titin truncations in the C-terminal two-thirds of the protein, sugges
Externí odkaz:
https://doaj.org/article/64ef752df04c4b96ab2dff639a70afb6
Autor:
Ryan Jorgensen, Meghna Katta, Jayne Wolfe, Desiree F. Leach, Bianca Lavelle, Jerold Chun, Lisa D. Wilsbacher
Publikováno v:
Physiological Reports, Vol 9, Iss 19, Pp n/a-n/a (2021)
Abstract Sphingosine 1‐Phosphate receptor 1 (S1P1, encoded by S1pr1) is a G protein‐coupled receptor that signals in multiple cell types including endothelial cells and cardiomyocytes. Cardiomyocyte‐specific deletion of S1pr1 during mouse devel
Externí odkaz:
https://doaj.org/article/f0fa5bd3dcfa47a086f6af6cfe439e69
Autor:
Rahul Rai, Suresh K. Verma, David Kim, Veronica Ramirez, Elizabeth Lux, Chengjin Li, Susmita Sahoo, Lisa D. Wilsbacher, Douglas E. Vaughan, Susan E. Quaggin, Asish K. Ghosh
Publikováno v:
Epigenetics, Vol 12, Iss 11, Pp 1004-1013 (2017)
Hypertension-associated end-organ damage commonly leads to cardiac and renal fibrosis. As no effective anti-fibrotic therapy currently exists, the unchecked progression of fibrogenesis manifests as cardio-renal failure and early death. We have previo
Externí odkaz:
https://doaj.org/article/7dbce0f1f066420eaf5a8232a891d531
Autor:
Asish K, Ghosh, Anthony A, Kalousdian, Meng, Shang, Elizabeth, Lux, Mesut, Eren, Anna, Keating, Lisa D, Wilsbacher, Douglas E, Vaughan
Publikováno v:
Cellular Signalling. 104:110555
Plasminogen activator inhibitor-1 (PAI-1) is a specific and rapid-acting inhibitor of endogenous plasminogen activators (uPA and tPA). The global PAI-1 knockout mice (PAI-1KO) develop age-dependent cardiac-selective fibrosis, and young global PAI-1KO
Autor:
Juan Pablo Portocarrero, Ahsun Riaz, Andrew W. Hoel, Lisa D. Wilsbacher, Jane DeMatte D′Amico, Lisa Dellefave-Castillo, Anjana V. Yeldandi, James Paparello
Publikováno v:
Circulation: Genomic and Precision Medicine. 14
Autor:
Bianca Lavelle, Jayne Wolfe, Jerold Chun, Ryan Jorgensen, Meghna Katta, Desiree F. Leach, Lisa D. Wilsbacher
Publikováno v:
Physiological Reports, Vol 9, Iss 19, Pp n/a-n/a (2021)
Physiological Reports
Physiological Reports
Sphingosine 1‐Phosphate receptor 1 (S1P1, encoded by S1pr1) is a G protein‐coupled receptor that signals in multiple cell types including endothelial cells and cardiomyocytes. Cardiomyocyte‐specific deletion of S1pr1 during mouse development le
Autor:
Lisa D. Wilsbacher, Matthew DeBerge, Connor Lantz, Hans W.M. Niessen, Daniel J. Brat, Edward B. Thorp, Shirley Dehn, Matthew J. Feinstein, David P. Sullivan, Sunjay Kaushal, Anja M. van der Laan, Margaret E. Flanagan
Publikováno v:
Journal of Experimental Medicine, 218(9):e20200667. Rockefeller University Press
DeBerge, M, Lantz, C, Dehn, S, Sullivan, D P, van der Laan, A M, Niessen, H W M, Flanagan, M E, Brat, D J, Feinstein, M J, Kaushal, S, Wilsbacher, L D & Thorp, E B 2021, ' Hypoxia-inducible factors individually facilitate inflammatory myeloid metabolism and inefficient cardiac repair ', Journal of Experimental Medicine, vol. 218, no. 9, e20200667 . https://doi.org/10.1084/jem.20200667
Journal of experimental medicine, 218(9):e20200667. Rockefeller University Press
DeBerge, M, Lantz, C, Dehn, S, Sullivan, D P, van der Laan, A M, Niessen, H W M, Flanagan, M E, Brat, D J, Feinstein, M J, Kaushal, S, Wilsbacher, L D & Thorp, E B 2021, ' Hypoxia-inducible factors individually facilitate inflammatory myeloid metabolism and inefficient cardiac repair ', Journal of Experimental Medicine, vol. 218, no. 9, e20200667 . https://doi.org/10.1084/jem.20200667
Journal of experimental medicine, 218(9):e20200667. Rockefeller University Press
Hypoxia-inducible factors (HIFs) are activated in parenchymal cells in response to low oxygen and as such have been proposed as therapeutic targets during hypoxic insult, including myocardial infarction (MI). HIFs are also activated within macrophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acccee7cfaea54a5f78cc9724e1272d1
https://research.vumc.nl/en/publications/79e0d475-3f92-46b1-817b-d34d20229f9b
https://research.vumc.nl/en/publications/79e0d475-3f92-46b1-817b-d34d20229f9b
Autor:
Ryan Avery, Andre Y. Son, Michael Markl, Maurice Pradella, Bradley A. Allen, S. Chris Malaisrie, Lisa D. Wilsbacher, Nicole M. DeMarais, Jon W. Lomasney
Publikováno v:
Circulation. Cardiovascular imaging. 14(6)
Autor:
Ira Tabas, Edward B. Thorp, Kristofor Glinton, Lisa D. Wilsbacher, Carla V. Rothlin, Manikandan Subramanian, Matthew DeBerge
Publikováno v:
J Clin Invest
Tyro3, AXL, and MerTK (TAM) receptors are activated in macrophages in response to tissue injury and as such have been proposed as therapeutic targets to promote inflammation resolution during sterile wound healing, including myocardial infarction. Al
Autor:
Sean Yamakawa, Glenn I. Fishman, J. Sell, Ibrahim Tahtah, Elizabeth M. McNally, Megan J Pickelwartz, Michael Broman, Lisa D. Wilsbacher, Brigitte Laforest, Andrew Wasserstrom, David Y. Barefield
Publikováno v:
Circulation Research. 127
A premature truncation variant in MYBPHL in humans and a loss of Mybphl in mice associates with dilated cardiomyopathy (DCM), atrial and ventricular arrhythmias, and atrial enlargement. MYBPHL encodes myosin binding protein H-like (MyBP-HL) and is ex