Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Lisa D, Muiznieks"'
Autor:
Hansen Wang, Lisa D Muiznieks, Punam Ghosh, Declan Williams, Michael Solarski, Andrew Fang, Alejandro Ruiz-Riquelme, Régis Pomès, Joel C Watts, Avi Chakrabartty, Holger Wille, Simon Sharpe, Gerold Schmitt-Ulms
Publikováno v:
eLife, Vol 6 (2017)
The amyloid β peptide (Aβ) is a key player in the etiology of Alzheimer disease (AD), yet a systematic investigation of its molecular interactions has not been reported. Here we identified by quantitative mass spectrometry proteins in human brain e
Externí odkaz:
https://doaj.org/article/335a92b94e58463380f20574bebf20a3
Publikováno v:
Langmuir. 35:15364-15375
Deposition of calcium phosphate minerals on the elastin-rich medial layers of arteries can cause severe cardiovascular complications. There are no available treatments for medial calcification, and the mechanism of mineral formation on elastin layers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874e79d646b508a7898ab6e2d82dbef1
https://doi.org/10.1021/acs.langmuir.9b02542
https://doi.org/10.1021/acs.langmuir.9b02542
Publikováno v:
Matrix Biology. 84:68-80
Elastin is the polymeric protein responsible for the physiologically important properties of extensibility and elastic recoil of cardiovascular, pulmonary and many other tissues. In spite of significant advances in the understanding how monomeric tro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6f3ea8ae4755e9057cd4d1fc86de6c
https://doi.org/10.1016/j.matbio.2019.06.010
https://doi.org/10.1016/j.matbio.2019.06.010
Autor:
Lisa D. Muiznieks, Fred W. Keeley
Publikováno v:
ACS biomaterials scienceengineering. 3(5)
Elastic biomaterials are found across biology where they fulfill diverse load-bearing and energy storage and dissipation functions. This class of biomaterials comprises elastic proteins that provide materials with combinations of extensibility, stiff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48f76931173ea51b5ecb166d7afa76b
https://pubmed.ncbi.nlm.nih.gov/33440501
https://pubmed.ncbi.nlm.nih.gov/33440501
Autor:
Régis Pomès, Eva E. Sitarz, Christopher Ing, Simon Sharpe, Sean E. Reichheld, Nick Wang, Lisa D. Muiznieks, Quang Huynh, Fred W. Keeley, Ming Miao
Publikováno v:
BiopolymersREFERENCES. 112(2)
Elastin is a major polymeric protein of the extracellular matrix, providing critical properties of extensibility and elastic recoil. The rs2071307 genomic polymorphism, resulting in the substitution of a serine for a glycine residue in a VPG motif in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9153a7e37016536955ac29914558dfd6
https://pubmed.ncbi.nlm.nih.gov/33351193
https://pubmed.ncbi.nlm.nih.gov/33351193
Autor:
Ophélie Gourgas, Abhinav Parashar, Simon Sharpe, Monzur Murshed, Jingjing Li, Lisa D. Muiznieks, Kirk Lau, Elaine C. Davis, Marta Cerruti
Publikováno v:
Journal of structural biology. 213(1)
Medial calcification has been associated with diabetes, chronic kidney disease, and genetic disorders like pseudoxanthoma elasticum. Recently, we showed that genetic reduction of arterial elastin content reduces the severity of medial calcification i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c960e7accc4cb75a16ab509381fcc7
https://pubmed.ncbi.nlm.nih.gov/33059036
https://pubmed.ncbi.nlm.nih.gov/33059036
Autor:
David He, Ming Miao, Eva E Sitarz, Lisa D Muiznieks, Sean Reichheld, Richard J Stahl, Fred W Keeley, John Parkinson
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46130 (2012)
Elastin is a major structural component of elastic fibres that provide properties of stretch and recoil to tissues such as arteries, lung and skin. Remarkably, after initial deposition of elastin there is normally no subsequent turnover of this prote
Externí odkaz:
https://doaj.org/article/019c51074db1484ca69fa12ab39056e9
Publikováno v:
Journal of Molecular Biology. 430:4741-4753
Liquid-liquid phase separation resulting in formation of colloidal droplets has recently attracted attention as a mechanism for rapid and transient assembly of intracellular macromolecules into functional units. Phase separation also appears to be a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d41e1f23a8f485d2affb87c2c6ca96
https://doi.org/10.1016/j.jmb.2018.06.010
https://doi.org/10.1016/j.jmb.2018.06.010
Autor:
Antonio Nanci, Dainelys Guadarrama Bello, Ophélie Gourgas, Marta Cerruti, Simon Sharpe, Lisa D. Muiznieks
Publikováno v:
Biomacromolecules. 20(7)
Calcium phosphate minerals deposit on the elastin-rich medial layers of arteries in the majority of seniors, diabetic, and chronic kidney disease patients, causing severe cardiovascular complications. There is no cure for medial calcification, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37cd1e29641148a3c98e31622b761db
https://pubmed.ncbi.nlm.nih.gov/31244014
https://pubmed.ncbi.nlm.nih.gov/31244014
Autor:
Lisa D. Muiznieks, Fred W. Keeley
Publikováno v:
Biopolymers. 105:693-703
Elastin and silk spidroins are fibrous, structural proteins with elastomeric properties of extension and recoil. While elastin is highly extensible and has excellent recovery of elastic energy, silks are particularly strong and tough. This study desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d74b3be8f8a50c6a523caa2f62df04c
https://doi.org/10.1002/bip.22888
https://doi.org/10.1002/bip.22888