Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lisa Cooper-Charles"'
Autor:
Patricia Ramos, María José Sánchez-Soler, Alison Stewart, Nicolas Chassaing, Jonathan Bruty, Patrick Calvas, Domingo Aguilera-Garcia, Helen Stewart, Dominic J. McMullan, Dorine Bax, Yvonne Wallis, Alan Fryer, Anand Saggar, Carmen Ayuso, Cristina Villaverde, Fabiola Ceroni, Marta Corton, Luciana Rodrigues Jacy da Silva, Lisa Cooper-Charles, Michael J. Griffiths, Victoria McKay, Jonathan Hoffman, Maria Tarilonte, David J. Bunyan, María Juliana Ballesta-Martínez, Nicola K. Ragge, Richard J. Holt, Katherine Lachlan, Fiona Blanco-Kelly, Joelle Roume, Pascal Dureau
Publikováno v:
Human Genetics
Human Genetics, 2019, 138 (8-9), pp.1027-1042. ⟨10.1007/s00439-018-1875-2⟩
Human Genetics, 2019, 138 (8-9), pp.1027-1042. ⟨10.1007/s00439-018-1875-2⟩
International audience; GJA8 encodes connexin 50 (Cx50), a transmembrane protein involved in the formation of lens gap junctions. GJA8 mutations have been linked to early onset cataracts in humans and animal models. In mice, missense mutations and ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122f27747b3dc12ebac73973e54e0086
https://ut3-toulouseinp.hal.science/hal-03542896
https://ut3-toulouseinp.hal.science/hal-03542896
Autor:
Dominic J. McMullan, Jenny Elizabeth Morton, Chirag Patel, Judith M. Walker, Lisa Cooper-Charles, Val Davison
Publikováno v:
European Journal of Human Genetics. 19:634-639
Gilles de la Tourette syndrome is a complex neuropsychiatric disorder with a strong genetic basis. We identified a male patient with Tourette syndrome-like tics and an apparently balanced de novo translocation [46,XY,t(2;7)(p24.2;q31)]. Further analy
Autor:
Zubair Ahmed, Ann Logan, Martin L. Read, Lisa Cooper-Charles, Karen Sims, Martin Berry, Ana Maria Gonzalez
Publikováno v:
Molecular and Cellular Neuroscience. 39:411-417
Adenovirus (Ad) is an efficient and safe vector for CNS gene delivery since it infects non-replicating neurons and does not cause insertional mutagenesis of host cell genomes. However, the promiscuous Ad CAR receptor targets cells non-specifically an
Autor:
Ann Logan, Lisa Cooper-Charles, Karen Sims, Brian P. Eliceiri, Oscar Berlanga, Wendy Leadbeater, Ana Maria Gonzalez, Martin Berry, Andrew Baird
Publikováno v:
The journal of gene medicine. 11(8)
Background In previous studies, we showed that gene activated matrices (GAMs) containing nonviral vectors successfully deliver genes to neurons after optic nerve and spinal cord injury. In the present study, we evaluated whether adenoviral vectors de
Autor:
Leonard W. Seymour, Martin L. Read, Ana Maria Gonzalez, Ann Logan, Kerry D. Fisher, Karen Sims, Zubair Ahmed, Lisa Cooper-Charles, Martin Berry
Publikováno v:
The journal of gene medicine. 11(4)
Background Polymer coating of adenovirus type 5 (Ad5) particles produces a ‘stealth’ Ad5 (sAd5) that confers protection from immune recognition, blocks receptor-mediated uptake, and favours uptake into pinocytic cells. Methods In mixed cultures o