Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lisa Conyers"'
Autor:
Polina Kosillo, Natalie M. Doig, Kamran M. Ahmed, Alexander H.C.W. Agopyan-Miu, Corinna D. Wong, Lisa Conyers, Sarah Threlfell, Peter J. Magill, Helen S. Bateup
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Tuberous Sclerosis Complex (TSC) is a neurodevelopmental disorder caused by mutations in the TSC1 or TSC2 genes, which negatively regulate mTORC1 signalling. Here the authors selectively delete Tsc1 from dopamine neurons in mice and find impairments
Externí odkaz:
https://doaj.org/article/8f206497b65e4d93a92d89d476e37c28
Autor:
Natalie M. Doig, Peter J. Magill, Lisa Conyers, Alexander H.C.W. Agopyan-Miu, Polina Kosillo, Kamran M. Ahmed, Sarah Threlfell, Corinna D. Wong, Helen S. Bateup
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Nature Communications
Nature Communications, vol 10, iss 1
Nature communications, vol 10, iss 1
Nature Communications
Nature Communications, vol 10, iss 1
Nature communications, vol 10, iss 1
Tuberous Sclerosis Complex (TSC) is a neurodevelopmental disorder caused by mutations in TSC1 or TSC2, which encode proteins that negatively regulate mTOR complex 1 (mTORC1). TSC is associated with significant cognitive, psychiatric, and behavioral p
Autor:
Peter J. Magill, Alexander H.C.W. Agopyan-Miu, Lisa Conyers, Kamran M. Ahmed, Sarah Threlfell, Polina Kosillo, Natalie M. Doig, Helen S. Bateup
SummarymTOR complex 1 (mTORC1) is a central coordinator of cell growth and metabolism. Mutations in regulators of mTORC1 cause syndromic disorders with a high prevalence of cognitive and psychiatric conditions. To elucidate the cellular origins of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2528c25a56131a1eb39dc4fe11146d3
https://doi.org/10.1101/376814
https://doi.org/10.1101/376814
Autor:
Phil Harvey, Lisa Conyers
Why is the welfare system failing to work for so many people? This book examines the problems with the current welfare system and proposes reforms to create a smarter, smaller system that helps people improve their lives through rewarding work.Unlike
Autor:
L. McCardle, Mark Penney, Azra C. Ghani, Lisa Conyers, Diane Ritchie, James W. Ironside, David A Hilton, Philip Edwards, Doha Hegazy
Publikováno v:
The Journal of pathology. 203(3)
This study aims to provide an estimate of the number of individuals in the UK who may be incubating variant Creutzfeldt-Jakob disease and at risk of causing iatrogenic spread of the disease. Lymphoreticular accumulation of prion protein is a consiste
Autor:
M E F Smith, Philip Edwards, Lisa Conyers, Mark Head, L. McCardle, James W. Ironside, J Sutak, Diane Ritchie, C A Wiley, David A Hilton, Mark Penney
Publikováno v:
Journal of clinical pathology. 57(3)
Background: Immunocytochemical accumulation of prion protein (PrP) in lymphoid tissues is a feature of variant Creutzfeldt–Jakob disease (vCJD) that has been used both to aid in the diagnosis of patients and as a basis of large scale screening stud
Autor:
Lisa Conyers, Azra C. Ghani, James W. Ironside, Philip Edwards, L. McCardle, Diane Ritchie, David A Hilton, Mark Penney
Publikováno v:
Hilton, D A, Ghani, A C, Conyers, L, Edwards, P, McCardle, L, Penney, M, Ritchie, D & Ironside, J W 2002, ' Accumulation of prion protein in tonsil and appendix : review of tissue samples ', British Medical Journal (BMJ), vol. 325, no. 7365, pp. 633-4 . https://doi.org/10.1136/bmj.325.7365.633
Variant Creutzfeldt-Jakob disease is almost certainly caused by the bovine spongiform encephalopathy agent, and although the disease is rare (115 deaths to date) there is uncertainty about future numbers of cases.1 The lack of a conventional immune r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7ad3a62803563c0e0473d070a5494c
https://researchonline.lshtm.ac.uk/id/eprint/13190/1/633.full.pdf
https://researchonline.lshtm.ac.uk/id/eprint/13190/1/633.full.pdf
Autor:
Diana Best, David A Hilton, James W. Ironside, Nicola J Johnston, L. McCardle, Azra C. Ghani, Lisa Conyers
Publikováno v:
Lancet (London, England). 355(9216)
To identify individuals who could be at high risk of developing vCJD, a sensitive immunohistochemical technique was used to detect prion protein in a retrospective series of over 3000 tonsil and appendix specimens. No positives were detected but furt
Publikováno v:
Brain research. 514(1)
We have used the extracellular spike triggered averaging method to obtain evidence for a monosynaptic connexion of single V (trigeminal) interneurones, located in the region immediately caudal to the V motor nucleus, onto neurones within the contrala