Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lisa C. Wallace"'
Autor:
Sajina Shakya, Anthony D. Gromovsky, James S. Hale, Arnon M. Knudsen, Briana Prager, Lisa C. Wallace, Luiz O. F. Penalva, H. Alex Brown, Bjarne W. Kristensen, Jeremy N. Rich, Justin D. Lathia, J. Mark Brown, Christopher G. Hubert
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract Glioblastoma (GBM) displays marked cellular and metabolic heterogeneity that varies among cellular microenvironments within a tumor. Metabolic targeting has long been advocated as a therapy against many tumors including GBM, but how lipid me
Externí odkaz:
https://doaj.org/article/f740fb738c5c45e4ad68a8ab8f9b28c9
Autor:
Swetha J. Sundar, Sajina Shakya, Austin Barnett, Lisa C. Wallace, Hyemin Jeon, Andrew Sloan, Violette Recinos, Christopher G. Hubert
Publikováno v:
Translational Oncology, Vol 15, Iss 1, Pp 101251- (2022)
Background: Glioblastoma (GBM) is the most common primary brain tumor with a dismal prognosis. The inherent cellular diversity and interactions within tumor microenvironments represent significant challenges to effective treatment. Traditional cultur
Externí odkaz:
https://doaj.org/article/7a95975469164d588ba4aae539bafb71
Autor:
Jeremy N. Rich, David R. Raleigh, Arie Perry, Lukas Chavez, Stephen C. Mack, Michael A. Vogelbaum, Gene H. Barnett, Clark Chen, Qi Xie, Xiuxing Wang, Jair L. Siqueira-Neto, Zhe Zhu, Melike Pekmezci, Ryan C. Gimple, Andrew R. Morton, Bradley H. King, Derrick Lee, Shruti Bhargava, Lisa C. Wallace, Qiulian Wu, Jean A. Bernatchez, Deobrat Dixit, Harish N. Vasudevan, Briana C. Prager
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efd6e3900ec62331fc2b995d845b0f8
https://doi.org/10.1158/2159-8290.22535467.v1
https://doi.org/10.1158/2159-8290.22535467.v1
Autor:
Jeremy N. Rich, David R. Raleigh, Arie Perry, Lukas Chavez, Stephen C. Mack, Michael A. Vogelbaum, Gene H. Barnett, Clark Chen, Qi Xie, Xiuxing Wang, Jair L. Siqueira-Neto, Zhe Zhu, Melike Pekmezci, Ryan C. Gimple, Andrew R. Morton, Bradley H. King, Derrick Lee, Shruti Bhargava, Lisa C. Wallace, Qiulian Wu, Jean A. Bernatchez, Deobrat Dixit, Harish N. Vasudevan, Briana C. Prager
Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8fc12739fe084a9affabbcf17bde21
https://doi.org/10.1158/2159-8290.22535461
https://doi.org/10.1158/2159-8290.22535461
Autor:
Jeremy N. Rich, David R. Raleigh, Arie Perry, Lukas Chavez, Stephen C. Mack, Michael A. Vogelbaum, Gene H. Barnett, Clark Chen, Qi Xie, Xiuxing Wang, Jair L. Siqueira-Neto, Zhe Zhu, Melike Pekmezci, Ryan C. Gimple, Andrew R. Morton, Bradley H. King, Derrick Lee, Shruti Bhargava, Lisa C. Wallace, Qiulian Wu, Jean A. Bernatchez, Deobrat Dixit, Harish N. Vasudevan, Briana C. Prager
Meningiomas are the most common primary intracranial tumor with current classification offering limited therapeutic guidance. Here, we interrogated meningioma enhancer landscapes from 33 tumors to stratify patients based upon prognosis and identify n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b303e4c689467c3cf881ea0c43acd9ef
https://doi.org/10.1158/2159-8290.c.6547867.v1
https://doi.org/10.1158/2159-8290.c.6547867.v1
Autor:
Harish N. Vasudevan, Arie Perry, Zhe Zhu, Deobrat Dixit, Jeremy N. Rich, Qi Xie, Jean A. Bernatchez, Andrew R. Morton, Derrick Lee, Lisa C. Wallace, Qiulian Wu, Jair L. Siqueira-Neto, David R. Raleigh, Ryan C. Gimple, Briana C. Prager, Shruti Bhargava, Xiuxing Wang, Clark C. Chen, Stephen C. Mack, Gene H. Barnett, Melike Pekmezci, Lukas Chavez, Bradley H. King, M.A. Vogelbaum
Publikováno v:
Cancer Discovery. 10:1722-1741
Meningiomas are the most common primary intracranial tumor with current classification offering limited therapeutic guidance. Here, we interrogated meningioma enhancer landscapes from 33 tumors to stratify patients based upon prognosis and identify n
Autor:
H. Alex Brown, J. Mark Brown, Jeremy N. Rich, Justin D. Lathia, Luiz O. F. Penalva, Briana C. Prager, Arnon Møldrup Knudsen, Sajina Shakya, Christopher G. Hubert, Bjarne Winther Kristensen, Anthony D. Gromovsky, James S. Hale, Lisa C. Wallace
Publikováno v:
Shakya, S, Gromovsky, A D, Hale, J S, Knudsen, A M, Prager, B, Wallace, L C, Penalva, L O F, Brown, H A, Kristensen, B W, Rich, J N, Lathia, J D, Brown, J M & Hubert, C G 2021, ' Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches ', Acta Neuropathologica Communications, vol. 9, 101 . https://doi.org/10.1186/s40478-021-01205-7
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
BackgroundGlioblastoma (GBM) is marked by cellular heterogeneity, including metabolic heterogeneity, that varies among cellular microenvironments in the same tumor. Altered cellular metabolism in cancer is well-established, but how lipid metabolism i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f771c8bce9d113f49f80845ee84e7a6e
https://findresearcher.sdu.dk:8443/ws/files/183278150/s40478_021_01205_7.pdf
https://findresearcher.sdu.dk:8443/ws/files/183278150/s40478_021_01205_7.pdf
Publikováno v:
Brain Tumors ISBN: 9781071608555
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a548731df55bec1538f16928d3053653
https://doi.org/10.1007/978-1-0716-0856-2_7
https://doi.org/10.1007/978-1-0716-0856-2_7
Autor:
Swetha J. Sundar, Lisa C. Wallace, Sajina Shakya, Violette Recinos, Austin Barnett, Christopher G. Hubert, Andrew E. Sloan
Publikováno v:
Neuro-Oncology. 23:vi201-vi201
BACKGROUND Glioblastoma (GBM) is the most common primary brain tumor with a dismal prognosis. The inherent cellular diversity and interactions within tumor microenvironments represent a significant challenge to effective treatment. Traditional cultur
Autor:
Ryan C. Gimple, Xiuxing Wang, Leo J.Y. Kim, Xun Jin, Andrew E. Sloan, Shideng Bao, Qiulian Wu, Ping Huang, Jeremy N. Rich, Jill S. Barnholtz-Sloan, Briana C. Prager, Lisa C. Wallace, Claudia L.L. Valentim, Tyler E. Miller, Tanwarat Sanvoranart, Stephen C. Mack, Qi Gang Zhou
Publikováno v:
Nature medicine
Glioblastomas are lethal cancers defined by angiogenesis and pseudopalisading necrosis. Here, we demonstrate that these histological features are associated with distinct transcriptional programs, with vascular regions showing a proneural profile and