Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lisa C. Schmitt"'
Autor:
Roland E. Kontermann, Meike Hutt, Sina Fellermeier-Kopf, Lisa C. Schmitt, Oliver Seifert, Klaus Pfizenmaier
Publikováno v:
Oncotarget
Fusion proteins combining hexavalent TRAIL with antibody fragments allow for a targeted delivery and efficient apoptosis induction in tumor cells. Here, we analyzed scFv-Fc-scTRAIL molecules directed against EGFR, HER2, HER3, and EpCAM as well as an
Autor:
Simone Schmid, Christine Sers, Michaela Strotbek, Yvonne Möller, Thomas E. Mürdter, Roland E. Kontermann, Lisa C. Schmitt, Pamela Riemer, Janina Hendrick, Sven Beyes, Markus Morkel, Monilola A. Olayioye, Jens O Schmid, Matthias Schwab
Publikováno v:
Oncotarget
// Yvonne Moller 1 , Markus Morkel 2 , Jens Schmid 3 , Sven Beyes 1, 8 , Janina Hendrick 1 , Michaela Strotbek 1 , Pamela Riemer 2, 4 , Simone Schmid 1 , Lisa C. Schmitt 1 , Roland Kontermann 1, 5 , Thomas Murdter 3 , Matthias Schwab 3, 6, 7 , Christ
Autor:
Stefan Dübel, Jonas Zantow, Roland E. Kontermann, Monilola A. Olayioye, Alexander Rau, Lisa C. Schmitt, Oliver Seifert, Simone Schmid, Michael Hust, Jonas Honer, Meike Hutt
Human epidermal growth factor receptor 3 (HER3, also known as ErbB3) has emerged as relevant target for antibody-mediated tumor therapy. Here, we describe a novel human antibody, IgG 3-43, recognizing a unique epitope formed by domain III and parts o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0794ff4771a71f93368c57a7bdde5494
https://europepmc.org/articles/PMC5524165/
https://europepmc.org/articles/PMC5524165/
Autor:
Franziska M. Uhl, Sandra Braun, Lisa C. Schmitt, Robert Zeiser, Björn Schorch, Martin Köhler, Wolfgang W. A. Schamel, Michael Röring, Katharina Heilmann, Sebastian Herzog, Florian Weinberg, Gina J. Fiala, Thorsten Kaltenbacher, Hassan Jumaa, Sophia Ehrenfeld, Natalie Stickel, Tilman Brummer
Publikováno v:
The EMBO journal. 35(2)
Despite being mutated in cancer and RASopathies, the role of the activation segment (AS) has not been addressed for B-Raf signaling in vivo. Here, we generated a conditional knock-in mouse allowing the expression of the B-Raf(AVKA) mutant in which th
Autor:
Wolfgang W. A. Schamel, Lisa C. Schmitt, Anja Meyer, Anja E. Eisenhardt, Sumit Deswal, Oreste Acuto, Tilman Brummer, Gina J. Fiala, Mogjiborahman Salek
Publikováno v:
The Journal of Immunology; Vol 190
The Journal of Immunology
The Journal of Immunology
The activation kinetics of MAPK Erk are critical for T cell development and activation. In particular, sustained Erk signaling is required for T cell activation and effector functions, such as IL-2 production. Although Raf-1 triggers transient Erk ac