Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Lisa C. Parker"'
Autor:
Elizabeth K. Marsh, Elizabeth C. Prestwich, Lynne Williams, Amber R. Hart, Clare F. Muir, Lisa C. Parker, Marnix R. Jonker, Irene H. Heijink, Wim Timens, Mark Fife, Tracy Hussell, Marc B. Hershenson, J. Kelley Bentley, Shao-Cong Sun, Ben S. Barksby, Lee A. Borthwick, James P. Stewart, Ian Sabroe, David H. Dockrell, Helen M. Marriott
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Exposure to respiratory pathogens is a leading cause of exacerbations of airway diseases such as asthma and chronic obstructive pulmonary disease (COPD). Pellino-1 is an E3 ubiquitin ligase known to regulate virally-induced inflammation. We wished to
Externí odkaz:
https://doaj.org/article/c5942d2d51cf4be9955c03b1925a6bc9
Autor:
Jake T. Mills, Anja Schwenzer, Elizabeth K. Marsh, Michael R. Edwards, Ian Sabroe, Kim S. Midwood, Lisa C. Parker
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Viral infections are a common cause of asthma exacerbations, with human rhinoviruses (RV) the most common trigger. RV signals through a number of different receptors, including toll-like receptor (TLR)3. Tenascin-C (TN-C) is an immunomodulatory extra
Externí odkaz:
https://doaj.org/article/e7a67144e351488b88dd613666419504
Publikováno v:
Thorax
The lungs are exposed to a range of environmental toxins (including cigarette smoke, air pollution, asbestos) and pathogens (bacterial, viral and fungal), and most respiratory diseases are associated with local or systemic hypoxia. All of these adver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259cb20239a1949f65d7beac59c41c9c
http://europepmc.org/articles/PMC7803888
http://europepmc.org/articles/PMC7803888
Autor:
Mark E. Fife, Marnix R. Jonker, Elizabeth K. Marsh, Shao Cong Sun, Clare F. Muir, Lynne Williams, J. Kelley Bentley, Wim Timens, Ian Sabroe, Irene H. Heijink, Ben S. Barksby, Helen M. Marriott, James P. Stewart, Marc B. Hershenson, David H. Dockrell, Tracy Hussell, Amber R. Hart, Elizabeth C. Prestwich, Lee A. Borthwick, Lisa C. Parker
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Frontiers in Cellular and Infection Microbiology, 10:456. Frontiers Media SA
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Frontiers in Cellular and Infection Microbiology, 10:456. Frontiers Media SA
Exposure to respiratory pathogens is a leading cause of exacerbations of airway diseases such as asthma and chronic obstructive pulmonary disease (COPD). Pellino-1 is an E3 ubiquitin ligase known to regulate virally-induced inflammation. We wished to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972dea53ebef5c744abf5dacd1b28327
https://doi.org/10.3389/fcimb.2020.00456
https://doi.org/10.3389/fcimb.2020.00456
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 3, p 678 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 3, p 678 (2019)
Inflammatory airway disease, such as asthma and chronic obstructive pulmonary disease (COPD), is a major health burden worldwide. These diseases cause large numbers of deaths each year due to airway obstruction, which is exacerbated by respiratory vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e03501a96e338a4f3a8a0fd27135c95
http://europepmc.org/articles/PMC6387402
http://europepmc.org/articles/PMC6387402
Autor:
Lisa C. Parker, Ian Sabroe, Irene H. Heijink, A. R. Hart, Lynne Williams, J. K. Bentley, Wim Timens, Shao Cong Sun, Lee A. Borthwick, Clare F. Muir, Ben S. Barksby, Helen M. Marriott, James P. Stewart, Mark E. Fife, Tracy Hussell, Marnix R. Jonker, Elizabeth K. Marsh, Marc B. Hershenson, David H. Dockrell, Elizabeth C. Prestwich
Publikováno v:
The influence of influenza: from cells to humans.
Introduction and objectives Exposure to respiratory pathogens is a leading cause of exacerbations of airway diseases such as asthma and chronic obstructive pulmonary disease (COPD). We have shown that Pellino-1, an E3 ubiquitin ligase, is involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a6f29ba5cecba12f1c13f4808cdbf74
https://doi.org/10.1136/thorax-2018-212555.104
https://doi.org/10.1136/thorax-2018-212555.104
DUSP10 Negatively Regulates the Inflammatory Response to Rhinovirus through Interleukin-1β Signaling
Publikováno v:
Journal of Virology
Rhinoviruses are one of the causes of the common cold. In patients with asthma or chronic obstructive pulmonary disease, viral infections, including those with rhinovirus, are the commonest cause of exacerbations. Novel therapeutics to limit viral in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ffb972cfac8f724313da6256843121
https://pubmed.ncbi.nlm.nih.gov/30333178
https://pubmed.ncbi.nlm.nih.gov/30333178
Publikováno v:
Cellular insights into lung injury repair.
Rational and Hypothesis Human Rhinovirus (HRV) infections are major contributors to the increased morbidity burden associated with asthma and COPD acute exacerbations. There are currently no effective treatments or vaccines targeting exacerbations, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c71145929312493e4f752ab1c9f2f25b
https://doi.org/10.1136/thoraxjnl-2017-210983.197
https://doi.org/10.1136/thoraxjnl-2017-210983.197
Publikováno v:
Clinical & Experimental Allergy. 44:20-28
Human rhinoviruses (HRV) have been linked to the development of childhood asthma and recurrent acute asthma exacerbations throughout life, and contribute considerably to the healthcare and economic burden of this disease. However, the ability of HRV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13df531bdf21664e12e6e63fa1f51bb6
https://doi.org/10.1111/cea.12182
https://doi.org/10.1111/cea.12182
Autor:
Sarah R. Walmsley, Lynne R. Prince, Clare A. Stokes, Stefanie N. Vogel, Elizabeth C. Prestwich, Ruth A. Sabroe, Lisa C. Parker, Lynne Bingle, Alexander Basran, Kathryn R. Higgins, Ian Sabroe, David H. Dockrell, Heather L. Wilson, Moira K. B. Whyte, Maisha Jabeen
Publikováno v:
Basran, A, Jabeen, M, Bingle, L, Stokes, C A, Dockrell, D, Whyte, M K B, Walmsley, S R, Higgins, K R, Vogel, S N, Wilson, H L, Prince, L R, Prestwich, E C, Sabroe, R A, Parker, L C & Sabroe, I 2013, ' Roles of neutrophils in the regulation of the extent of human inflammation through delivery of IL-1 and clearance of chemokines ', Journal of Leukocyte Biology, vol. 93, no. 1, pp. 7-19 . https://doi.org/10.1189/jlb.0512250
Endotoxin-induced neutrophil recruitment in humans and its potential regulation by CXCL8 clearance. This study examined the establishment of neutrophilic inflammation in humans. We tested the hypotheses that neutrophil recruitment was associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af1213f054c7b9e2ad09c2b6d7ab332
https://doi.org/10.1189/jlb.0512250
https://doi.org/10.1189/jlb.0512250