Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Lisa C, Osborne"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Autoimmune disorders are complex diseases of unclear etiology, although evidence suggests that the convergence of genetic susceptibility and environmental factors are critical. In type 1 diabetes (T1D), enterovirus infection and disruption of the int
Externí odkaz:
https://doaj.org/article/8ee04fe0539643468c7df49e99ccfe3e
Autor:
Michelle Zuo, Naomi M. Fettig, Louis-Philippe Bernier, Elisabeth Pössnecker, Shoshana Spring, Annie Pu, Xianjie I. Ma, Dennis S.W. Lee, Lesley A. Ward, Anshu Sharma, Jens Kuhle, John G. Sled, Anne-Katrin Pröbstel, Brian A. MacVicar, Lisa C. Osborne, Jennifer L. Gommerman, Valeria Ramaglia
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
People living with multiple sclerosis (MS) experience episodic CNS white matter lesions instigated by autoreactive T cells. With age, patients with MS show evidence of gray matter demyelination and experience devastating nonremitting symptomology. Wh
Externí odkaz:
https://doaj.org/article/3179dda5d85f4c3d98777afc0ce6961d
Autor:
Heather A Filyk, Lisa C Osborne
Publikováno v:
EBioMedicine, Vol 13, Iss C, Pp 46-54 (2016)
Mammalian evolution has occurred in the presence of mutualistic, commensal, and pathogenic micro- and macro-organisms for millennia. The presence of these organisms during mammalian evolution has allowed for intimate crosstalk between these colonizin
Externí odkaz:
https://doaj.org/article/dffc2002094f4cad88f36fa216ae16c3
Autor:
Leah S, Hohman, Lisa C, Osborne
Publikováno v:
Immunity. 55:1148-1150
A plethora of studies have established the importance of eosinophils in protective immunity against infections and in allergy. In this issue of Immunity, Ignacio et al. (2022) define a vital for eosinophils in coordinating a microbiota-epithelial-imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad6d009867725b9822fcace26afb2d8
https://doi.org/10.1016/j.immuni.2022.06.015
https://doi.org/10.1016/j.immuni.2022.06.015
Autor:
Isobel C. Mouat, Jessica R. Allanach, Naomi M. Fettig, Vina Fan, Anna M. Girard, Iryna Shanina, Lisa C. Osborne, Galina Vorobeychik, Marc S. Horwitz
Publikováno v:
Science advances. 8(47)
While age-associated B cells (ABCs) are known to expand and persist following viral infection and during autoimmunity, their interactions are yet to be studied together in these contexts. Here, we directly compared CD11c + T-bet + ABCs using models o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407a3154cf8f74168e260898fd3534cc
https://pubmed.ncbi.nlm.nih.gov/36427301
https://pubmed.ncbi.nlm.nih.gov/36427301
Autor:
Timothy J Nice, Lisa C Osborne, Vesselin T Tomov, David Artis, E John Wherry, Herbert W Virgin
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006223 (2017)
[This corrects the article DOI: 10.1371/journal.ppat.1005684.].
Externí odkaz:
https://doaj.org/article/6e89a54d79ce4a1db5b0b3e9e035bf66
Autor:
Naomi M Fettig, Hannah G Robinson, Jessica R Allanach, Katherine M Davis, Rachel L Simister, Elsie J Wang, Andrew J Sharon, Ye Jiayu, Sarah J Popple, Jung Hee Seo, Deanna L Gibson, Sean A Crowe, Marc S Horwitz, Lisa C Osborne
SummaryDietary fibers are potent modulators of immune responses that can restrain inflammation in multiple disease contexts. However, dietary fibers encompass a biochemically diverse family of carbohydrates, and it remains unknown how different fiber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e26e660dfd771d3ecfb9e67a37a9c486
https://doi.org/10.1101/2022.08.04.502686
https://doi.org/10.1101/2022.08.04.502686
Autoimmune disorders like type 1 diabetes (T1D) are complex diseases caused by numerous factors including both genetic variance and environmental influences. Two such exogenous factors, intestinal microbial composition and enterovirus infection, have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edc3caf1e4a6d6c9d8e35a35ee54acd5
https://doi.org/10.1101/2022.07.08.499212
https://doi.org/10.1101/2022.07.08.499212
Autor:
Leah S. Hohman, Lisa C. Osborne
Publikováno v:
Aging cell. 21(9)
Intestinal epithelial cells (IECs) serve as both a physical and an antimicrobial barrier against the microbiota, as well as a conduit for signaling between the microbiota and systemic host immunity. As individuals age, the balance between these syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9117a788af81a80051af930264abc5eb
https://pubmed.ncbi.nlm.nih.gov/36000805
https://pubmed.ncbi.nlm.nih.gov/36000805
Autor:
Lisa C. Osborne
Publikováno v:
Neuron. 109:3545-3547
Neurons of the enteric nervous system (ENS) have limited regenerative capacity, and damage to these cells can cause neuropathies. In a recent issue of Cell, Ahrends et al. (2021) demonstrate that muscularis macrophages integrate distinct signals from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5d8a58b9011a81c615059eb32b48278
https://doi.org/10.1016/j.neuron.2021.10.037
https://doi.org/10.1016/j.neuron.2021.10.037