Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Lisa Bastarache"'
Autor:
Jonathan D. Mosley, John P. Shelley, Alyson L. Dickson, Jacy Zanussi, Laura L. Daniel, Neil S. Zheng, Lisa Bastarache, Wei-Qi Wei, Mingjian Shi, Gail P. Jarvik, Elisabeth A. Rosenthal, Atlas Khan, Alborz Sherafati, Iftikhar J. Kullo, Theresa L. Walunas, Joseph Glessner, Hakon Hakonarson, Nancy J. Cox, Dan M. Roden, Stephan G. Frangakis, Brett Vanderwerff, C. Michael Stein, Sara L. Van Driest, Scott C. Borinstein, Xiao-Ou Shu, Matthew Zawistowski, Cecilia P. Chung, Vivian K. Kawai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Polygenic variation unrelated to disease contributes to interindividual variation in baseline white blood cell (WBC) counts, but its clinical significance is uncharacterized. We investigated the clinical consequences of a genetic predisposit
Externí odkaz:
https://doaj.org/article/aac9cb1b2aa64c909fbdd66e307ed326
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101192- (2024)
Externí odkaz:
https://doaj.org/article/6c6e7df8f290468dbd231ce68de89399
P818: Data from electronic healthcare records expands our understanding of X-linked genetic diseases
Autor:
Rory Tinker, Lisa Bastarache, Kimberly Ezell, Serena Neumann, Yutaka Furuta, Karee Morgan, John Phillips
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101729- (2024)
Externí odkaz:
https://doaj.org/article/6c4b7e38f32040e0bd50b9f9b165ac37
Autor:
Elly Brokamp, Lisa Bastarache, Nancy Cox, Rizwan Hamid, Nikhil K. Khanakari, Gillian Hooker, Megan Shuey
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 3-3 (2024)
OBJECTIVES/GOALS: Congenital anomalies (CAs) affect 3% of live births, yet the cause of 80% of CAs is unknown and for the 20% with an identified cause, variability in penetrance suggests additional risk drivers exist. Our method for identifying and c
Externí odkaz:
https://doaj.org/article/5fb762e36fbd42b8ae887315d9edea30
Autor:
Daniel B. Larach, Adam Lewis, Lisa Bastarache, Anita Pandit, Jing He, Anik Sinha, Nicholas J. Douville, Michael Heung, Michael R. Mathis, Jonathan D. Mosley, Jonathan P. Wanderer, Sachin Kheterpal, Matthew Zawistowski, Chad M. Brummett, Edward D. Siew, Cassianne Robinson-Cohen, Miklos D. Kertai
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background Prior studies support a genetic basis for postoperative acute kidney injury (AKI). We conducted a genome-wide association study (GWAS), assessed the clinical utility of a polygenic risk score (PRS), and estimated the heritable com
Externí odkaz:
https://doaj.org/article/813edc1012fa4c88a501d1fbf8d0c6be
Autor:
Patrick Allaire, Jing He, John Mayer, Luke Moat, Peter Gerstenberger, Reynor Wilhorn, Sierra Strutz, David S.L. Kim, Chenjie Zeng, Nancy Cox, Jerry W. Shay, Joshua Denny, Lisa Bastarache, Scott Hebbring
Publikováno v:
HGG Advances, Vol 4, Iss 3, Pp 100201- (2023)
Summary: Many epidemiologic studies have identified important relationships between leukocyte telomere length (LTL) with genetics and health. Most of these studies have been significantly limited in scope by focusing predominantly on individual disea
Externí odkaz:
https://doaj.org/article/6d78ffb73da14b06ada708fe5fdd4135
Autor:
Nicholas J. Douville, Daniel B. Larach, Adam Lewis, Lisa Bastarache, Anita Pandit, Jing He, Michael Heung, Michael Mathis, Jonathan P. Wanderer, Sachin Kheterpal, Ida Surakka, Miklos D. Kertai
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: The recent integration of genomic data with electronic health records has enabled large scale genomic studies on a variety of perioperative complications, yet genome-wide association studies on acute kidney injury have been limited in siz
Externí odkaz:
https://doaj.org/article/6e9fe0d4416b4fc6be7ccf6f263fab07
Autor:
Rory Tinker, Lisa Bastarache, Kimberly Ezell, Shilpa Nadimpalli Kobren, Cecilia Esteves, Rizwan Hamid, Joy Cogan, David Rinker, Souhrid Mukharjee, John A. Phillips
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100356- (2023)
Externí odkaz:
https://doaj.org/article/201094f8fada469c856210fc46cb9e68
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100326- (2023)
Externí odkaz:
https://doaj.org/article/31a1439f5f2e43ab9b21a38933de079c
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100705- (2023)
Externí odkaz:
https://doaj.org/article/09b9a822a46f4f1bae2729dfda4bbbc6