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pro vyhledávání: '"Lisa B Lee"'
Autor:
Lisa B Lee, Enaksha R Wickremsinhe
Publikováno v:
Bioanalysis. 13:711-724
Aim: Bioanalytical methods undergo many revisions and modifications throughout drug development to meet the objectives of the study and development program. Results: Validated LC–MS/MS methodology used to quantify abemaciclib and four metabolites i
Incorporating dried blood spot LC–MS/MS analysis for clinical development of a novel oncolytic agent
Autor:
Chris A. Schmalz, Sophie Callies, Lisa B Lee, Darlene K. Satonin, Enaksha R Wickremsinhe, Elizabeth Smith Labell
Publikováno v:
Bioanalysis. 10:341-356
Aim: Design and execution of a dried blood spot (DBS-LC–MS/MS) assay for pharmacokinetic analyses in oncology patients. Results & discussion: The methodology was validated to collect and store DBS samples from multiple clinical sites, and analyze b
Autor:
Enaksha R Wickremsinhe, Lisa B Lee
Publikováno v:
Bioanalysis. 10(21)
Incurred sample reanalysis (ISR) is used to ensure the validity and reliability of bioanalytical data. Additionally, ISR results also help identify issues that could influence or bias the data. Overall, based on a decade of experimental data generate
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 932
In this study we report a high sensitive method for the simultaneous analysis of LY2334737 (2'-deoxy-2',2'-difluoro-N-(1-oxo-2-propylpentyl)-cytidine), an amide prodrug of gemcitabine (2', 2'-difluoro-deoxycytidine), along with its active drug gemcit
Autor:
Jennifer S. Haas, Dean Sonneborn, Lisa B. Lee, Su-Ying Liang, Kathryn A. Phillips, Celia P. Kaplan
Publikováno v:
American journal of public health. 93(12)
Objectives. We examined the effect of race, socioeconomic status, and health insurance status on the prevalence of overweight among children and adolescents. Methods. We studied an observational cohort from the 1996 Medical Expenditure Panel Survey H