Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Lisa A. Russell"'
Autor:
Brigid S. A. Davidson, Juliana Estefania Arcila-Galvis, Marco Trevisan-Herraz, Aneta Mikulasova, Chris A. Brackley, Lisa J. Russell, Daniel Rico
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The myeloma overexpressed gene (MYEOV) has been proposed to be a proto-oncogene due to high RNA transcript levels found in multiple cancers, including myeloma, breast, lung, pancreas and esophageal cancer. The presence of an open reading frame (ORF)
Externí odkaz:
https://doaj.org/article/1f694ffff3bd4f6489047d823ad5fb2c
Autor:
Simon Bomken, Amir Enshaei, Edward C. Schwalbe, Aneta Mikulasova, Yunfeng Dai, Masood Zaka, Kent T.M. Fung, Matthew Bashton, Huezin Lim, Lisa Jones, Nefeli Karataraki, Emily Winterman, Cody Ashby, Andishe Attarbaschi, Yves Bertrand, Jutta Bradtke, Barbara Buldini, G.A. Amos Burke, Giovanni Cazzaniga, Gudrun Gohring, Hesta A. de Groot-Kruseman, Claudia Haferlach, Luca Lo Nigro, Mayur Parihar, Adriana Plesa, Emma Seaford, Edwin Sonneveld, Sabine Strehl, Vincent H.J. van der Velden, Vikki Rand, Stephen P. Hunger, Christine J. Harrison, Chris M. Bacon, Frederik W. van Delft, Mignon L. Loh, John Moppett, Josef Vormoor, Brian A. Walker, Anthony V. Moorman, Lisa J. Russell
Publikováno v:
Haematologica, Vol 108, Iss 3 (2022)
Rarely, immunophenotypically immature B-cell precursor acute lymphoblastic leukemia (BCP-ALL) carries an immunoglobulin- MYC rearrangement (IG-MYC-r). This can result in diagnostic confusion with Burkitt lymphoma/leukemia and use of individualized tr
Externí odkaz:
https://doaj.org/article/7ac03037b4cc476bb5a3d391aea80fe8
Publikováno v:
Journal of Teaching and Learning with Technology, Vol 10, Iss 1 (2021)
This reflective essay describes steps taken by Business faculty in a U.S. Midwestern mid-sized regional university to assist faculty in making the rapid transition to 100% online teaching. These steps include the development of an online course templ
Externí odkaz:
https://doaj.org/article/a126f5a22bf94ed488928fd1b9b50b68
Autor:
Simon Bomken, Amir Enshaei, Edward C. Schwalbe, Aneta Mikulasova, Yunfeng Dai, Masood Zaka, Kent T.M. Fung, Matthew Bashton, Huezin Lim, Lisa Jones, Nefeli Karataraki, Emily Winterman, Cody Ashby, Andishe Attarbaschi, Yves Bertrand, Jutta Bradtke, Barbara Buldini, G.A. Amos Burke, Giovanni Cazzaniga, Gudrun Gohring, Hesta A. De Groot-Kruseman, Claudia Haferlach, Luca Lo Nigro, Mayur Parihar, Adriana Plesa, Emma Seaford, Edwin Sonneveld, Sabine Strehl, Vincent H.J. Van der Velden, Vikki Rand, Stephen P. Hunger, Christine J. Harrison, Chris M. Bacon, Frederik W. Van Delft, Mignon L. Loh, John Moppett, Josef Vormoor, Brian A. Walker, Anthony V. Moorman, Lisa J. Russell
Publikováno v:
Haematologica, 108(3), 717-731. Ferrata Storti Foundation
Rarely, immunophenotypically immature B-cell precursor acute lymphoblastic leukemia (BCP-ALL) carries an immunoglobulin- MYC rearrangement (IG-MYC-r). This can result in diagnostic confusion with Burkitt lymphoma/leukemia and use of individualized tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7411c7fc24485bab44d71b9c30d8a4
https://doi.org/10.3324/haematol.2021.280557
https://doi.org/10.3324/haematol.2021.280557
Autor:
Sarra L. Ryan, John F. Peden, Zoya Kingsbury, Claire J. Schwab, Terena James, Petri Polonen, Martina Mijuskovic, Jenn Becq, Richard Yim, Ruth E. Cranston, Dale J. Hedges, Kathryn G. Roberts, Charles G. Mullighan, Ajay Vora, Lisa J. Russell, Robert Bain, Anthony V. Moorman, David R. Bentley, Christine J. Harrison, Mark T. Ross
Publikováno v:
Leukemia. 37:518-528
Childhood B-cell acute lymphoblastic leukaemia (B-ALL) is characterised by recurrent genetic abnormalities that drive risk-directed treatment strategies. Using current techniques, accurate detection of such aberrations can be challenging, due to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd5f8e13d90983ff4cc84a74e249c523
https://doi.org/10.1038/s41375-022-01806-8
https://doi.org/10.1038/s41375-022-01806-8
Autor:
Claire Schwab, Ruth E. Cranston, Sarra L. Ryan, Ellie Butler, Emily Winterman, Zoe Hawking, Matthew Bashton, Amir Enshaei, Lisa J. Russell, Zoya Kingsbury, John F. Peden, Emilio Barretta, James Murray, Jude Gibson, Andrew C. Hinchliffe, Robert Bain, Ajay Vora, David R. Bentley, Mark T. Ross, Anthony V. Moorman, Christine J. Harrison
Publikováno v:
Leukemia. 37:529-538
Incorporating genetics into risk-stratification for treatment of childhood B-progenitor acute lymphoblastic leukaemia (B-ALL) has contributed significantly to improved survival. In about 30% B-ALL (B-other-ALL) without well-established chromosomal ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60403edb6229c7170ae8763141d22df5
https://doi.org/10.1038/s41375-022-01799-4
https://doi.org/10.1038/s41375-022-01799-4
Autor:
Paul Milne, Helen J. Blair, Cornelia Eckert, Zoya Kingsbury, Matthew Collin, Anetta Ptasinska, Alex Elder, Roderick Skinner, Janine Stutterheim, Jennifer Becq, Elena Zerkalenkova, Constanze Bonifer, Denis M. Schewe, Peter N. Cockerill, N Martinez-Soria, Oskar A. Haas, Peter Carey, Katarzyna Szoltysek, Deepali Pal, Hesta McNeill, Claus Meyer, Maria Rosaria Imperato, James C. Mulloy, Mark Wunderlich, Catherine Cargo, Paul Evans, Sarah E. Fordham, Shan Lin, Pierre Cauchy, Y Shi, Simon Bailey, Salam A. Assi, Rolf Marschalek, Josef Vormoor, Olaf Heidenreich, A Komkov, Michael J. Thirman, Simon Bomken, Ricky Tirtakusuma, Sirintra Nakjang, Fotini Vogiatzi, James M. Allan, Lisa J. Russell, Jayne Y. Hehir-Kwa, Muzlifah Haniffa, Yulia Olshanskaya, Vasily V. Grinev, Christine J. Harrison, Venetia Bigley, Daniel Williamson, Alex Smith, Natalia Miakova
Publikováno v:
Blood. 140:1875-1890
The fusion gene MLL-AF4 defines a high-risk subtype of pro-B acute lymphoblastic leukaemia. However, relapse can be associated with a switch from acute lymphoblastic to acute myeloid leukaemia. Here we show that these myeloid relapses share oncogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfc1d67bb85567d28d48decb91162f8
https://doi.org/10.1182/blood.2021015036
https://doi.org/10.1182/blood.2021015036
Autor:
Paul. B. Sinclair, Helen H. Blair, Sarra L. Ryan, Lars Buechler, Joanna Cheng, Jake Clayton, Rebecca Hanna, Shaun Hollern, Zoe Hawking, Matthew Bashton, Claire J. Schwab, Lisa Jones, Lisa J. Russell, Helen Marr, Peter Carey, Christina Halsey, Olaf Heidenreich, Anthony V. Moorman, Christine J. Harrison
Publikováno v:
Haematologica, Vol 103, Iss 4 (2018)
Intrachromosomal amplification of chromosome 21 is a heterogeneous chromosomal rearrangement occurring in 2% of cases of childhood precursor B-cell acute lymphoblastic leukemia. These abnormalities are too complex to engineer faithfully in animal mod
Externí odkaz:
https://doaj.org/article/061b963a6e4f465eb098f328b26facdc
Autor:
Cody Ashby, Brian A Walker, Marco Trevisan-Herraz, Sharmilan Thanendrarajan, Kent Fung, Agata Cieslak, Shmuel Yaccoby, Maurizio Zangari, Aneta Mikulasova, Daniel Rico, Vahid Asnafi, Lisa J. Russell, Nefeli Karataraki, Anne E. Corcoran, Daniel Kent, Sophie Hambleton, Carolina Schinke, Gareth J. Morgan, Salvatore Spicuglia, Frits van Rhee, Chris A. Brackley
Publikováno v:
Mikulasova, A, Kent, D, Trevisan-Herraz, M, Karataraki, N, Fung, K T M, Ashby, C, Cieslak, A, Yaccoby, S, van Rhee, F, Zangari, M, Thanendrarajan, S, Schinke, C, Morgan, G J, Asnafi, V, Spicuglia, S, Brackley, C A, Corcoran, A E, Hambleton, S, Walker, B A, Rico, D & Russell, L J 2021, ' Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers ', Genome Research, vol. 2022, 32, pp. 1343-1354 . https://doi.org/10.1101/gr.276042.121
Chromosomal translocations are important drivers of haematological malignancies whereby proto-oncogenes are activated by juxtaposition with enhancers, often called enhancer hijacking. We analysed the epigenomic consequences of rearrangements between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eedf4484dfbaf56189657b0745b5f853
https://doi.org/10.1101/gr.276042.121
https://doi.org/10.1101/gr.276042.121
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The goal of immunization is to produce both a flood of antibodies to neutralize antigen and memory cells to accelerate the secondary response. To enhance the generation of memory B cells, we examined the effect of co-engaging BCR and toll-like recept
Externí odkaz:
https://doaj.org/article/a375feb5dd224c028929d6d58ee48b55