Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Lisa A. Morici"'
Autor:
Michelle Galeas-Pena, Allyson Hirsch, Erin Kuang, Joseph Hoffmann, Patrick Gellings, Jasmine B. Brown, Vanessa M. Limbert, Claire L. Callahan, James B. McLachlan, Lisa A. Morici
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract Pertussis is a vaccine-preventable respiratory disease caused by the Gram negative coccobacillus Bordetella pertussis. The licensed acellular pertussis (aP) vaccines protect against disease but do not prevent bacterial colonization and trans
Externí odkaz:
https://doaj.org/article/ff82b04918334d96b5a42736516074f4
Autor:
John T. Prior, Vanessa M. Limbert, Rebecca M. Horowitz, Shaina J. D’Souza, Louay Bachnak, Matthew S. Godwin, David L. Bauer, Jaikin E. Harrell, Lisa A. Morici, Justin J. Taylor, James B. McLachlan
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract Although most pathogens infect the human body via mucosal surfaces, very few injectable vaccines can specifically target immune cells to these tissues where their effector functions would be most desirable. We have previously shown that cert
Externí odkaz:
https://doaj.org/article/638c80db4344406292b9c8eca00fb6bf
Autor:
Yihui Wang, Joseph P. Hoffmann, Sarah M. Baker, Kerstin Höner zu Bentrup, William C. Wimley, Joseph A. Fuselier, Jacob P. Bitoun, Lisa A. Morici
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Biofilms are microbial communities surrounded by a self-produced extracellular matrix which protects them from environmental stress. Bacteria within biofilms are 10- to 1000-fold more resistant to antibiotics, making it challengin
Externí odkaz:
https://doaj.org/article/a404412068b94913a0083574a378a3b7
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Chronic respiratory infection (CRI) with Pseudomonas aeruginosa (Pa) presents many unique challenges that complicate treatment. One notable challenge is the hypermutator phenotype which is present in up to 60% of sampled CRI patient isolates. Hypermu
Externí odkaz:
https://doaj.org/article/cc7526ee6b5546c2bd8f1b500eca0a46
Autor:
Sarah M. Baker, Erik W. Settles, Christopher Davitt, Patrick Gellings, Nicole Kikendall, Joseph Hoffmann, Yihui Wang, Jacob Bitoun, Kasi-Russell Lodrigue, Jason W. Sahl, Paul Keim, Chad Roy, James McLachlan, Lisa A. Morici
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Burkholderia pseudomallei is a Gram-negative, facultative intracellular bacillus that causes the disease melioidosis. B. pseudomallei expresses a number of proteins that contribute to its intracellular survival in the mammalian host. We prev
Externí odkaz:
https://doaj.org/article/94ff28ca65e5414195014839c12c40a0
Autor:
Robert J. Hart, Lisa A. Morici
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The bacterium Pseudomonas aeruginosa (Pa) is ubiquitous in the environment and causes opportunistic infections in humans. Pa is increasingly becoming one of the most difficult to treat microorganisms due to its intrinsic and acquired resistance to mu
Externí odkaz:
https://doaj.org/article/5c9b4ecbaa274b20800fe77e4569b50f
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 2, Pp 412-418 (2020)
Pseudomonas aeruginosa is an opportunistic human pathogen capable of causing a wide range of potentially life-threatening infections. With multidrug-resistant P. aeruginosa infections on the rise, the need for a rationally-designed vaccine against th
Externí odkaz:
https://doaj.org/article/ee94469c56ab47e1ae2f7e289b0f3a09
Autor:
Li Yang, Te Liang, Lane M. Pierson, Hongye Wang, Jesse K. Fletcher, Shu Wang, Duran Bao, Lili Zhang, Zhen Huang, Wenshu Zheng, Xiaomei Zhang, Heewon Park, Yuwen Li, James E. Robinson, Amy K. Feehan, Christopher J. Lyon, Jing Cao, Lisa A. Morici, Chenzhong Li, Chad J. Roy, Xiaobo Yu, Tony Hu
Publikováno v:
Research, Vol 2022 (2022)
Identification of epitopes targeted following virus infection or vaccination can guide vaccine design and development of therapeutic interventions targeting functional sites, but can be laborious. Herein, we employed peptide microarrays to map linear
Externí odkaz:
https://doaj.org/article/3c5565859db147acb09b4f31677d9342
Autor:
Joseph P. Hoffmann, Jessica K. Friedman, Yihui Wang, James B. McLachlan, Mimi C. Sammarco, Lisa A. Morici, Chad J. Roy
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
Increased prevalence of antibiotic resistance in skin and soft tissue infections is a concerning public health challenge currently facing medical science. A combinatory, broad spectrum biocidal antiseptic has been developed (“ASP”) as a topically
Externí odkaz:
https://doaj.org/article/cf3afcab25b2431da8b68c20f296d889
An Outer Membrane Vesicle-Adjuvanted Oral Vaccine Protects Against Lethal, Oral Salmonella Infection
Autor:
Jaikin E. Harrell, Jonathan R. Kurtz, David L. Bauer, J. Timothy Prior, Patrick S. Gellings, Lisa A. Morici, James B. McLachlan
Publikováno v:
Pathogens, Vol 10, Iss 5, p 616 (2021)
Non-typhoidal salmonellosis, caused by Salmonella enterica serovar Typhimurium is a common fecal-oral disease characterized by mild gastrointestinal distress resulting in diarrhea, chills, fever, abdominal cramps, head and body aches, nausea, and vom
Externí odkaz:
https://doaj.org/article/6aef9d7d4536401c8b64aa1b108a6708