Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lisa A. Majuta"'
Autor:
Lisa A. Majuta, Jean-Marc G. Guedon, Stefanie A.T. Mitchell, Michael A. Kuskowski, Patrick W. Mantyh
Publikováno v:
PAIN Reports, Vol 2, Iss 5, p e614 (2017)
Abstract. Introduction:. Cancer-induced bone pain (CIBP) is the most common type of pain with cancer. In humans, this pain can be difficult to control and highly disabling. A major problem with CIBP in humans is that it increases on weight-bearing an
Externí odkaz:
https://doaj.org/article/72b6241c34274ad09fc0d44f6a85393e
Publikováno v:
Neuroscience. 387:178-190
Although bone is continually being remodeled and ultimately declines with aging, little is known whether similar changes occur in the sensory and sympathetic nerve fibers that innervate bone. Here, immunohistochemistry and confocal microscopy were us
Publikováno v:
Pain. 159:2285-2295
Anti-nerve growth factor (anti-NGF) therapy has shown significant promise in attenuating several types of skeletal pain. However, whether anti-NGF therapy changes the level of physical activity in individuals with or without skeletal pain is largely
Publikováno v:
Current Osteoporosis Reports. 16:325-332
PURPOSE OF REVIEW: This paper describes recent advances in understanding the mechanisms that drive fracture pain and how these findings are helping develop new therapies to treat fracture pain. RECENT FINDINGS: Immediately following fracture, mechano
Autor:
Stefanie A.T. Mitchell, Jean Marc G. Guedon, Michael H. Ossipov, Lisa A. Majuta, Patrick W. Mantyh
Publikováno v:
Pain. 158:605-617
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) are 2 of the most common and successful surgical interventions to relieve osteoarthritis pain. Control of postoperative pain is critical for patients to fully participate in the required
Autor:
Michelle N. Fealk, Jean Marc G. Guedon, Lisa A. Majuta, Patrick W. Mantyh, Geraldine Longo, Michelle L. Thomspon
Publikováno v:
Pain. 157:1239-1247
Recent studies have suggested that in humans and animals with significant skeletal pain, changes in the mechanical hypersensitivity of the skin can be detected. However, whether measuring changes in skin hypersensitivity can be a reliable surrogate f
Publikováno v:
Pain. 156:157-165
The number of patients suffering from postoperative pain due to orthopedic surgery and bone fracture is projected to dramatically increase because the human life span, weight, and involvement in high-activity sports continue to rise worldwide. Joint
Autor:
Patrick W. Mantyh, Lisa A. Majuta, Michael A. Kuskowski, Stefanie A.T. Mitchell, Jean Marc G. Guedon
Publikováno v:
Pain Reports
PAIN Reports, Vol 2, Iss 5, p e614 (2017)
PAIN Reports, Vol 2, Iss 5, p e614 (2017)
Supplemental Digital Content is Available in the Text. Mice with bone cancer have reduced peak day/night activity. Therapeutically blocking this decline may improve the activity level of patients with painful bone metastases.
Introduction: Cance
Introduction: Cance
Autor:
Geraldine Longo, Lisa A. Majuta, Michelle N. Fealk, Stephane R. Chartier, Patrick W. Mantyh, Michelle L. Thompson, Gwen McCaffrey
Publikováno v:
Cancer Research. 74:7014-7023
Studies in animals and humans show that blockade of nerve growth factor (NGF) attenuates both malignant and nonmalignant skeletal pain. While reduction of pain is important, a largely unanswered question is what other benefits NGF blockade might conf
Autor:
Patrick W. Mantyh, Lisa A. Majuta, Michelle L. Thompson, Michelle N. Fealk, Geraldine Longo, Stephane R. Chartier
Publikováno v:
Pain. 155:2323-2336
Skeletal injury is a leading cause of chronic pain and long-term disability worldwide. While most acute skeletal pain can be effectively managed with nonsteroidal anti-inflammatory drugs and opiates, chronic skeletal pain is more difficult to control