Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lisa A. Falls"'
Autor:
Hamid A. Al-Mondhiry, Rehana S. Lovely, Gary Sexton, Lisa A. Falls, Hanyu Ni, David H. Farrell, Charles E. Chambers
Publikováno v:
Thrombosis and Haemostasis. 88:26-31
SummaryγA/γ’ fibrinogen is a fibrinogen isoform that constitutes about 15% of total plasma fibrinogen. This isoform contains an additional binding site for zymogen factor XIII and for active thrombin, and forms fibrin clots that are resistant to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4b2505c4b8af8d4e6826c18267527e6
https://doi.org/10.1055/s-0037-1613148
https://doi.org/10.1055/s-0037-1613148
Publikováno v:
Journal of Biological Chemistry. 276:23895-23902
The hydrophobic omega-loop within the prothrombin gamma-carboxyglutamic acid-rich (Gla) domain is important in membrane binding. The role of this region in membrane binding was investigated using a synthetic peptide, PT-(1-46)F4W, which includes the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb70f1f7cd64f24e5143e245725b4f05
https://doi.org/10.1074/jbc.m008332200
https://doi.org/10.1074/jbc.m008332200
Publikováno v:
Blood. 95:2586-2592
Coagulation factor XIIIa is a transglutaminase that catalyzes covalent cross-link formation in fibrin clots. In this report, we demonstrate that factor XIIIa also mediates adhesion of endothelial cells and inhibits capillary tube formation in fibrin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::965ea6ac3910db60592de3b7b4081742
https://doi.org/10.1182/blood.v95.8.2586.008k04_2586_2592
https://doi.org/10.1182/blood.v95.8.2586.008k04_2586_2592
Publikováno v:
Blood. 95:2586-2592
Coagulation factor XIIIa is a transglutaminase that catalyzes covalent cross-link formation in fibrin clots. In this report, we demonstrate that factor XIIIa also mediates adhesion of endothelial cells and inhibits capillary tube formation in fibrin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06a709ba0a973b025e3ad66a097536f8
https://doi.org/10.1182/blood.v95.8.2586
https://doi.org/10.1182/blood.v95.8.2586
Autor:
David H. Farrell, Lisa A. Falls
Publikováno v:
Journal of Biological Chemistry. 272:14251-14256
Elevated plasma fibrinogen levels are a major risk factor for thrombosis. This report shows two mechanisms by which fibrinogen can affect the fibrinolysis rate in vitro and thus may lead to thrombosis. First, the lysis rate of fibrin decreases as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db20d57a5c977817bb23e936e0126045
https://doi.org/10.1074/jbc.272.22.14251
https://doi.org/10.1074/jbc.272.22.14251
Autor:
Rehana S, Lovely, Lisa A, Falls, Hamid A, Al-Mondhiry, Charles E, Chambers, Gary J, Sexton, Hanyu, Ni, David H, Farrell
Publikováno v:
Thrombosis and haemostasis. 88(1)
GammaA/gamma' fibrinogen is a fibrinogen isoform that constitutes about 15% of total plasma fibrinogen. This isoform contains an additional binding site for zymogen factor XIII and for active thrombin, and forms fibrin clots that are resistant to fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::083a99cab33df3999868e7ce92b84687
https://pubmed.ncbi.nlm.nih.gov/12152671
https://pubmed.ncbi.nlm.nih.gov/12152671
Publikováno v:
Biochemistry. 39(43)
Phospholipid membranes play a significant role during the proteolytic activation of blood coagulation proteins. This investigation identifies a role for phosphatidylethanolamine (PE) during the activation of factor X by the tenase complex, an enzymat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f7c2623cf066c1a197caad997e825e
https://pubmed.ncbi.nlm.nih.gov/11052674
https://pubmed.ncbi.nlm.nih.gov/11052674
Publikováno v:
Journal of Biological Chemistry. 275:35656
Factor XIII zymogen activation is a complex series of events that involve fibrinogen acting in several different roles. This report focuses on the role of fibrinogen as a cofactor in factor XIII activation by thrombin. We demonstrate that fibrinogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afb4ea93ccd96232bc94606672aefe8
https://doi.org/10.1016/s0021-9258(20)88878-4
https://doi.org/10.1016/s0021-9258(20)88878-4