Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lisa A. Dunning"'
Publikováno v:
Steroids. 69:67-70
Cortisol is metabolized to 6beta-hydroxycortisol by human cytochrome p450-3A4 (CYP3A4), an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds. Both cortisol and 6beta-hydroxycortisol are excreted in urine,
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 61(5)
The endoplasmic reticulum (ER) chaperones are highly conserved proteins that catalyze the posttranslational processing of all secretory and membrane proteins. Our studies suggest that chaperone declines are one of the two central defects in Alzheimer
Autor:
Jordan L. Holtzman, Douglas Olson, W. Gibson Wood, Sheftel J. Cohen, Lisa M. Dunning, Richard R. Erickson, Robert A. Kratzke, Alan T. Davis
Publikováno v:
Biochemical and biophysical research communications. 332(1)
The β-amyloids (abetas) are the major components of the plaque observed in the brains of patients with Alzheimer’s disease. The conundrum is that although they are produced in everyone during the posttranslational processing in the endoplasmic ret
Autor:
Jordan L. Holtzman, Zhi Chen, Rudolph S. Parrish, Kristin G. Anderson, Wei Zheng, Lisa M. Dunning
Publikováno v:
Steroids. 64(12)
The ratio of urinary 2-hydroxyestrone (2-OHE1) to 16alpha-hydroxyestrone (16alpha-OHE1) has been suggested as a potential biomarker for breast cancer risk. We evaluated within-person variability of this biomarker in ten healthy Caucasian women aged 2