Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lisa A. DeBruyne"'
Autor:
G. Alexander Patterson, Ronald K. Scheule, Jon M. Ritter, Lihui Qin, Mariano Boglione, Jonathan S. Bromberg, Carlos H.R. Boasquevisque, Lisa A. DeBruyne, Nelson S. Yew, Bassem N. Mora
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 119:913-920
Background: The aim of the current work was to study the feasibility of functional gene transfer using the gene encoding for transforming growth factor–β1, a known immunosuppressive cytokine, on rat lung allograft function in the setting of acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad85ab0aeb41976c78514e656ed8725
https://doi.org/10.1016/s0022-5223(00)70086-9
https://doi.org/10.1016/s0022-5223(00)70086-9
Publikováno v:
Gene Therapy. 5:1079-1087
The gene encoding the immunosuppressive cytokine viral interleukin-10 (vIL-10) was introduced into BALB/c (H-2d) vascularized cardiac allografts by perfusing the graft vasculature with DNA-liposome complexes, utilizing the experimental cationic lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb142a596eca00cf858ca9895bd3e11
https://doi.org/10.1038/sj.gt.3300694
https://doi.org/10.1038/sj.gt.3300694
Autor:
Lisa A. DeBruyne
Publikováno v:
Cancer Immunology, Immunotherapy. 43:180-189
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76719ebc478a0b53fabe4019251df96e
https://doi.org/10.1007/s002620050320
https://doi.org/10.1007/s002620050320
Publikováno v:
Transplant Immunology. 3:222-228
Mouse hearts transplanted into MHC disparate donors are usually rejected 1 week after placement. It is widely accepted that alloantigen-reactive helper T lymphocytes (HTL) and cytotoxic T lymphocytes (CTL) are the key mediators of acute allograft rej
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5fe93a3ca89348628723014e0db9f0
https://doi.org/10.1016/0966-3274(95)80028-x
https://doi.org/10.1016/0966-3274(95)80028-x
Publikováno v:
Transplantation. 59:1155-1161
A current hypothesis states that Th1 cytokines promote allograft rejection and that Th2 cytokines promote graft acceptance. We present data that question the tolerogenic activity of Th2 cytokines, and we suggest that Th2 cytokines may evoke allograft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfe4b59db6ed832d73b6850eafb71a63
https://doi.org/10.1097/00007890-199504270-00014
https://doi.org/10.1097/00007890-199504270-00014
Publikováno v:
Transplantation. 59:778-783
We have reported that acute cardiac allograft rejection is associated with increased numbers of donor-reactive helper T lymphocytes (HTL) in the peripheral blood of patients. Further, increased frequencies of circulating donor-reactive HTL may predic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509a9ca63d15ed898597be35f3fdcb0d
https://doi.org/10.1097/00007890-199503150-00024
https://doi.org/10.1097/00007890-199503150-00024
Publikováno v:
Trends in cardiovascular medicine. 6(5)
Cardiac allograft rejection is diagnosed by routine, surveillance endomyocardial biopsy (EMB). EMB is an invasive and expensive procedure that detects ongoing, rather than impending, rejection, and may be influenced by sampling error due to nonunifor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7dbc2aadc4cd2a968ee0753c1a487a8
https://pubmed.ncbi.nlm.nih.gov/21232292
https://pubmed.ncbi.nlm.nih.gov/21232292
Publikováno v:
Gene therapy. 7(7)
Introducing immunomodulatory molecules into allografts by gene transfer may avoid the side-effects of systemic immunosuppression. vMIP-II and MC148 are two recently identified chemokine homologues encoded by human herpes virus 8 and Molluscum contagi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69e88408939aa1ff6c952af3ef40466
https://pubmed.ncbi.nlm.nih.gov/10819572
https://pubmed.ncbi.nlm.nih.gov/10819572
Publikováno v:
Gene Therapy in Inflammatory Diseases ISBN: 9783034895842
Other chapters in this volume have focused on gene transfer approaches for inhibition of immune responses against autoantigens. This chapter will discuss treatment of inflammatory responses directed against alloantigens, as a result of allogeneic tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::866e681850b0f830318b1bf62ee11637
https://doi.org/10.1007/978-3-0348-8478-5_10
https://doi.org/10.1007/978-3-0348-8478-5_10
