Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Lisa A. Cassis"'
Autor:
Nancy E. Schoenberg, Jimmy Robinson, Margaret McGladrey, Lisa A. Cassis, Darwin Conwell, Kevin J. Pearson, Lisa R. Tannock, Donna Wilcock, Stephanie White
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Novel and comprehensive approaches are needed to address shortcomings in the diversity and inclusiveness of the scientific workforce. In response to this need and informed by multiple programs and data sources, we created the Rese
Externí odkaz:
https://doaj.org/article/f6fa21a4659c48498ca440730fcaa08c
Autor:
Nathalia Araujo, James Sledziona, Sunil K. Noothi, Ravshan Burikhanov, Nikhil Hebbar, Saptadwipa Ganguly, Tripti Shrestha-Bhattarai, Beibei Zhu, Wendy S. Katz, Yi Zhang, Barry S. Taylor, Jinze Liu, Li Chen, Heidi L. Weiss, Daheng He, Chi Wang, Andrew J. Morris, Lisa A. Cassis, Mariana Nikolova-Karakashian, Prabhakar R. Nagareddy, Olle Melander, B. Mark Evers, Philip A. Kern, Vivek M. Rangnekar
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Prostate apoptosis response-4 (Par-4) is a tumor suppressor that induces apoptosis in cancer cells. However, the physiological function of Par-4 remains unknown. Here we show that conventional Par-4 knockout (Par-4-/-) mice and adipocyte-specific Par
Externí odkaz:
https://doaj.org/article/4120df1ef9614b949185e69e897e61c9
Autor:
Robin Shoemaker, Lisa R. Tannock, Wen Su, Ming Gong, Susan B. Gurley, Sean E. Thatcher, Frederique Yiannikouris, Charles M. Ensor, Lisa A. Cassis
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-12 (2019)
Abstract Background Obesity increases the risk for hypertension in both sexes, but the prevalence of hypertension is lower in females than in males until menopause, despite a higher prevalence of obesity in females. We previously demonstrated that an
Externí odkaz:
https://doaj.org/article/532f89bb23e148a894a91d6d83f52fa8
Autor:
Yasir AlSiraj, Xuqi Chen, Sean E. Thatcher, Ryan E. Temel, Lei Cai, Eric Blalock, Wendy Katz, Heba M. Ali, Michael Petriello, Pan Deng, Andrew J. Morris, Xuping Wang, Aldons J. Lusis, Arthur P. Arnold, Karen Reue, Katherine Thompson, Patrick Tso, Lisa A. Cassis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Men and women differ in their risk of developing coronary artery disease, in part due to differences in their levels of sex hormones. Here, AlSiraj et al. show that the XX sex genotype regulates lipid metabolism and promotes atherosclerosis independe
Externí odkaz:
https://doaj.org/article/779e3daba0e549a3b1b7cf483d20172c
Autor:
Carolina Dalmasso, Jacqueline R. Leachman, Charles M. Ensor, Frederique B. Yiannikouris, Jorge F. Giani, Lisa A. Cassis, Analia S. Loria
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 23 (2019)
Background We have previously reported that female mice exposed to maternal separation and early weaning (MSEW), a model of early life stress, show exacerbated diet‐induced obesity associated with hypertension. The goal of this study was to test wh
Externí odkaz:
https://doaj.org/article/fa7e187606cb430f895dab134a3e251e
Publikováno v:
International Journal of Hypertension, Vol 2012 (2012)
Deficiency of ACE2 in macrophages has been suggested to promote the development of an inflammatory M1 macrophage phenotype. We evaluated effects of ACE2 deficiency in bone-marrow-derived stem cells on adipose inflammation and glucose tolerance in C57
Externí odkaz:
https://doaj.org/article/4a5937191a4847ada1a6e649cca50733
Publikováno v:
Arterioscler Thromb Vasc Biol
AngII (angiotensin II) infusion in mice has been used to provide mechanistic insight into human abdominal aortic aneurysms for over 2 decades. This is a technically facile animal model that recapitulates multiple facets of the human disease. Although
Autor:
Preetha Shridas, Ailing Ji, Andrea C. Trumbauer, Victoria P. Noffsinger, Steve W. Leung, Adam J. Dugan, Sean E. Thatcher, Lisa A. Cassis, Frederick C. de Beer, Nancy R. Webb, Lisa R. Tannock
Publikováno v:
Arterioscler Thromb Vasc Biol
Background: Obesity increases the risk for human abdominal aortic aneurysms (AAAs) and enhances Ang II (angiotensin II)–induced AAA formation in C57BL/6J mice. Obesity is also associated with increases in perivascular fat that expresses proinflamma
Autor:
Chen Zhang, Yanming Li, Abhijit Chakraborty, Yang Li, Kimberly R. Rebello, Pingping Ren, Wei Luo, Lin Zhang, Hong S. Lu, Lisa A. Cassis, Joseph S. Coselli, Alan Daugherty, Scott A. LeMaire, Ying H. Shen
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology.
Background: When aortic cells are under stress, such as increased hemodynamic pressure, they adapt to the environment by modifying their functions, allowing the aorta to maintain its strength. To understand the regulation of this adaptive response, w
Autor:
Ashley Dawson, Yanming Li, Yang Li, Pingping Ren, Hernan G. Vasquez, Chen Zhang, Kimberly R. Rebello, Waleed Ageedi, Alon R. Azares, Aladdein Burchett Mattar, Mary Burchett Sheppard, Hong S. Lu, Joseph S. Coselli, Lisa A. Cassis, Alan Daugherty, Ying H. Shen, Scott A. LeMaire
Publikováno v:
Genes, Vol 13, Iss 95, p 95 (2022)
Genes; Volume 13; Issue 1; Pages: 95
Genes
Genes; Volume 13; Issue 1; Pages: 95
Genes
The molecular and cellular processes leading to aortic aneurysm development in Marfan syndrome (MFS) remain poorly understood. In this study, we examined the changes of aortic cell populations and gene expression in MFS by performing single-cell RNA