Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Lisa A. Beyer"'
Autor:
Jingying Guo, Xiaobo Ma, Jennifer M. Skidmore, Jelka Cimerman, Diane M. Prieskorn, Lisa A. Beyer, Donald L. Swiderski, David F. Dolan, Donna M. Martin, Yehoash Raphael
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 319-333 (2021)
Pathogenic variants in GJB2, the gene encoding connexin 26, are the most common cause of autosomal-recessive hereditary deafness. Despite this high prevalence, pathogenic mechanisms leading to GJB2-related deafness are not well understood, and cures
Externí odkaz:
https://doaj.org/article/fa3d714e52b744348ecd08e357da7134
Autor:
Sungsu Lee, Jae-Jun Song, Lisa A. Beyer, Donald L. Swiderski, Diane M. Prieskorn, Melih Acar, Hsin-I Jen, Andrew K. Groves, Yehoash Raphael
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract Mature mammalian cochlear hair cells (HCs) do not spontaneously regenerate once lost, leading to life-long hearing deficits. Attempts to induce HC regeneration in adult mammals have used over-expression of the HC-specific transcription facto
Externí odkaz:
https://doaj.org/article/a5f302ca620148b1ae8d55867529301b
Publikováno v:
Engineering in Life Sciences, Vol 23, Iss 10, Pp n/a-n/a (2023)
Abstract Bacillus coagulans is a promising probiotic, because it combines probiotic properties of Lactobacillus and the ability of Bacillus to form endospores. Due to this hybrid relationship, cultivation of this organism is challenging. As the probi
Externí odkaz:
https://doaj.org/article/e497828011bc41eb8d87c86f257a4002
Autor:
Donald L. Swiderski, Lisa A. Beyer, Diane M. Prieskorn, Xiaobo Ma, Jelka Cimerman, Donna M. Martin, Jingying Guo, Jennifer M. Skidmore, Yehoash Raphael, David F. Dolan
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 319-333 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 319-333 (2021)
Pathogenic variants in GJB2, the gene encoding connexin 26, are the most common cause of autosomal-recessive hereditary deafness. Despite this high prevalence, pathogenic mechanisms leading to GJB2-related deafness are not well understood, and cures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3018be296187f55b8a379880280bda
https://doi.org/10.1016/j.omtm.2021.09.009
https://doi.org/10.1016/j.omtm.2021.09.009
Autor:
Elizabeth A. Hurd, K. Elaine Ritter, Jingxia Gao, Lisa A. Beyer, Donna M. Martin, Jelka Cimerman, Yehoash Raphael, Jennifer M. Skidmore, Vinodh Balendran
Publikováno v:
Dev Biol
Epigenetic regulation of gene transcription by chromatin remodeling proteins has recently emerged as an important contributing factor in inner ear development. Pathogenic variants in CHD7, the gene encoding Chromodomain Helicase DNA binding protein 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48818090c25942b125f17579365db6f7
https://doi.org/10.1016/j.ydbio.2021.05.009
https://doi.org/10.1016/j.ydbio.2021.05.009
Autor:
K. Elaine Ritter, Sloane M. Lynch, Ashley M. Gorris, Lisa A. Beyer, Lisa Kabara, David F. Dolan, Yehoash Raphael, Donna M. Martin
Publikováno v:
Hear Res
CHARGE syndrome is a multiple anomaly developmental disorder characterized by a variety of sensory deficits, including sensorineural hearing loss of unknown etiology. Most cases of CHARGE are caused by heterozygous pathogenic variants in CHD7, the ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd6d17784d251f4ef5ca2c15cf35c39
https://pubmed.ncbi.nlm.nih.gov/36288662
https://pubmed.ncbi.nlm.nih.gov/36288662
Autor:
Min Young Lee, Takaomi Kurioka, Megan M Nelson, Diane M Prieskorn, Donald L Swiderski, Yohei Takada, Lisa A Beyer, Yehoash Raphael
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Synaptopathy in the cochlea occurs when the connection between inner hair cells and the auditory nerve is disrupted, leading to impaired hearing and nerve degeneration. Experiments using transgenic mice have shown that overexpression of NT3 by suppor
Externí odkaz:
https://doaj.org/article/6106aef689604f4bbf84d17bcb8f8e51
Autor:
Hsin-I Jen, Donald L. Swiderski, Lisa A. Beyer, Jae-Jun Song, Yehoash Raphael, Melih Acar, Sungsu Lee, Andrew K. Groves, Diane M. Prieskorn
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Mature mammalian cochlear hair cells (HCs) do not spontaneously regenerate once lost, leading to life-long hearing deficits. Attempts to induce HC regeneration in adult mammals have used over-expression of the HC-specific transcription factor Atoh1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a82e56884f10c70f99dbd66d3c067ce
https://doi.org/10.1038/s41598-020-78167-8
https://doi.org/10.1038/s41598-020-78167-8
Autor:
K. Elaine Ritter, Sungsu Lee, Min Young Lee, Yehoash Raphael, Donald L. Swiderski, Takaomi Kurioka, Lisa A. Beyer
Publikováno v:
Neuroscience
The auditory sensory epithelium of the mammalian inner ear is a highly organized structure that contains sensory hair cells (HCs) and non-sensory supporting cells (SCs). Following the partial loss of HCs after cochlear insults such as overstimulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd9949640a816a80ed22ea4481631ac
https://pubmed.ncbi.nlm.nih.gov/33285239
https://pubmed.ncbi.nlm.nih.gov/33285239
Autor:
Donald L. Swiderski, Lisa A. Beyer, Bryan E. Pfingst, Yehoash Raphael, Jenna Devare, Deborah J. Colesa
Publikováno v:
Hear Res
Mice with chronic cochlear implants can significantly contribute to our understanding of the relationship between cochlear health and implant function because of the availability of molecular tools for controlling conditions in the cochlea and transg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944baf45315bf63b7c882e852f8a6529
https://doi.org/10.1016/j.heares.2021.108216
https://doi.org/10.1016/j.heares.2021.108216