Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lisa A. Alex"'
Autor:
Matthew G. Endrizzi, Li-Jun Ma, Ian T. Paulsen, Gregory O. Kothe, David B. Jaffe, David E. A. Catcheside, Edward M. Marcotte, Jonathan Butler, Giuseppe Macino, Matthew S. Sachs, David D. Perkins, Jerome Naylor, Oded Yarden, Nick O. Read, Shunguang Wang, Sarah E. Calvo, Reinhard Engels, J. Andrew Berglund, Nicole Stange-Thomann, Robert L. Metzenberg, Stephan Seiler, Scott Kroken, Seth Purcell, Dmitrij Frishman, Ulrich Schulte, Bruce W. Birren, Dayong Qui, Manolis Kamvysselis, Edward L. Braun, Gregory Jedd, Rodolfo Aramayo, Mary Anne Nelson, Sante Gnerre, Carlo Cogoni, Deborah Bell-Pedersen, Rodger B. Voelker, Chad Nusbaum, David Greenberg, Robert J. Pratt, Gertrud Mannhaupt, Bushra Rehman, Carolyn G. Rasmussen, Colin P.C. DeSouza, Michael Plamann, Weixi Li, Evan Mauceli, Daniel J. Ebbole, Katherine A. Borkovich, William Fitzhugh, Svetlana Krystofova, Peter Ianakiev, Claude P. Selitrennikoff, Stephen A. Osmani, Marc J. Orbach, Alice Roy, Jay C. Dunlap, Donald O. Natvig, Robert Barrett, Stephen Rudd, Louise Glass, James E. Galagan, Cord Bielke, Karen Foley, Alan Radford, John A. Kinsey, Michael Freitag, Chuck Staben, Lisa A. Alex, Alex Zelter, Cydney B. Nielsen, Margaret Werner-Washburne, Serge Smirnov, Timothy Elkins, Michael Kamal, Werner Mewes, Eric S. Lander, Eric U. Selker
Publikováno v:
Nature. 422:859-868
Neurospora crassa is a central organism in the history of twentieth-century genetics, biochemistry and molecular biology. Here, we report a high-quality draft sequence of the N. crassa genome. The approximately 40-megabase genome encodes about 10,000
Autor:
T. K. Miller, Claude P. Selitrennikoff, Lisa A. Alex, Melvin I. Simon, Karl V. Clemons, D A Stevens
Publikováno v:
Medical Mycology. 39:69-74
The human fungal pathogen, Candida albicans, has three putative histidine kinases showing homology to those of plants, bacteria and other fungi. We have constructed a homozygous deletion strain and a hemizygous reconstituted strain of one of these hi
Publikováno v:
Cell. 96:131-141
Histidine kinases allow bacteria, plants, and fungi to sense and respond to their environment. The 2.6 Å resolution crystal structure of Thermotoga maritima CheA (290-671) histidine kinase reveals a dimer where the functions of dimerization, ATP bin
Publikováno v:
Proceedings of the National Academy of Sciences. 95:7069-7073
Two-component histidine kinases recently have been found in eukaryotic organisms including fungi, slime molds, and plants. We describe the identification of a gene, COS1 , from the opportunistic pathogen Candida albicans by using a PCR-based screenin
Publikováno v:
Proceedings of the National Academy of Sciences. 93:3416-3421
Two-component signal transduction systems are most often found in prokaryotic organisms where they are responsible for mediating the cellular responses to many environmental stimuli. These systems are composed of an autophosphorylating histidine kina
Publikováno v:
Trends in Biochemical Sciences. 19:485-490
Autophosphorylating histidine kinase and response-regulator domains constitute the building blocks of two-component signaling systems. These systems use a unique phosphotransfer chemistry to regulate many aspects of bacterial physiology. Homologous s
Autor:
Melvin I. Simon, Lisa A. Alex
Publikováno v:
Trends in Genetics. 10:133-138
During the past several years, it has become apparent that prokaryotic organisms process much of their sensory information through families of similar proteins that make up two-component signal transducing systems. Biochemical and genetic analyses ha
Publikováno v:
Nature. 365:343-347
We have used surface plasmon resonance biosensor technology to monitor the assembly and dynamics of a signal transduction complex which controls chemotaxis in Escherichia coli. A quaternary complex formed which consisted of the response regulator Che
Publikováno v:
Biochemistry. 29:7237-7244
The genes frhA (1,217 bp), frhB (845 bp), and frhG (710 bp) encoding the three known subunits, {alpha}, {beta}, and {gamma}, of the 8-hydroxy-5-deazaflavin (F{sub 420}) reducing hydrogenase (FRH) from the thermophilic methanogen Methanobacterium ther
Autor:
Alex Zelter, Alan Radford, Chizu Ishii, Stephan Seiler, Ulrich Schulte, Jane Yeadon, Oded Yarden, Eric U. Selker, Robert Pratt, Michael Polymenis, George A. Marzluf, John V. Paietta, Michael Freitag, Marta Goodrich-Tanrikulu, Hirokazu Inoue, James E. Galagan, Nick D. Read, Frank E. Nargang, Ian T. Paulsen, Deborah Bell-Pedersen, Nora Plesofsky, Matthew S. Sachs, Jay C. Dunlap, Daniel J. Ebbole, Keiichiro Suzuki, David E. A. Catcheside, Eric R. Kalkman, Michael Plamann, Rowland H. Davis, Frederick J. Bowring, Claude P. Selitrennikoff, Lisa A. Alex, Rebecca O’Rourke, Jennifer J. Loros, Gertrud Mannhaupt, Gloria E. Turner, Wataru Sakai, Katherine A. Borkovich, Rodolfo Aramayo
Publikováno v:
Borkovich, KA; Alex, LA; Yarden, O; Freitag, M; Turner, GE; Read, ND; et al.(2004). Lessons from the Genome Sequence of Neurospora crassa: Tracing the Path from Genomic Blueprint to Multicellular Organism. Microbiology and Molecular Biology Reviews, 68(1), 1-108. doi: 10.1128/MMBR.68.1.1-108.2004. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/76h9307w
SUMMARY We present an analysis of over 1,100 of the ∼10,000 predicted proteins encoded by the genome sequence of the filamentous fungus Neurospora crassa . Seven major areas of Neurospora genomics and biology are covered. First, the basic features