Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Lisa A Opanashuk"'
Publikováno v:
Frontiers in Neuroanatomy, Vol 8 (2014)
Bisphenol-A (BPA) is a monomer used in the production of polycarbonate plastics, epoxies and resins and is present in many common household objects ranging from water bottles, can linings, baby bottles, and dental resins. BPA exposure has been linked
Externí odkaz:
https://doaj.org/article/c887ef82697d48699bf5a05e738695bb
Autor:
M. Kerry O'Banion, Deborah A. Cory-Slechta, Sarah E.A. McConnell, John A. Olschowka, Lisa A. Opanashuk
Publikováno v:
NeuroToxicology. 50:131-141
Methamphetamine (MA) is a potent, highly addictive psychostimulant abused by millions of people worldwide. MA induces neurotoxicity, damaging striatal dopaminergic terminals, and neuroinflammation, with striatal glial activation leading to pro-inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d160464a44db5c59b9cfa0fad95d82
https://doi.org/10.1016/j.neuro.2015.08.006
https://doi.org/10.1016/j.neuro.2015.08.006
Autor:
Zachariah O. Adham, Lisa A. Opanashuk, Daniel P. Dever, Emanuel DiCicco-Bloom, Matthieu Genestine, Bryan D. Thompson, Jonathan D. Cherry, John A. Olschowka
Publikováno v:
Developmental Neurobiology. 76:533-550
The aryl hydrocarbon receptor (AhR) is a ligand-activated member of the basic-helix-loop-helix/PER-ARNT-SIM(PAS) transcription factor superfamily that also mediates the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Increasing evidence sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa7d8874a6c780ef91910f81f06b256c
https://doi.org/10.1002/dneu.22330
https://doi.org/10.1002/dneu.22330
Publikováno v:
Journal of Neurochemistry. 125:430-445
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity of dioxin and serves multiple developmental roles. In the adult brain, while we now localize AhR mRNA to nestin-expressing neural progenitor cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176ff1e70008c1536ae2905d023d6734
https://doi.org/10.1111/jnc.12130
https://doi.org/10.1111/jnc.12130
Autor:
Lisa A. Opanashuk, Robert A. Gross, Bryan D. Thompson, Charles E. Heckler, Michelle C. Janelsins, Deborah A. Cory-Slechta
Background Cyclophosphamide chemotherapy is a mainstay of adjuvant breast cancer treatment. Unfortunately, this drug is associated with cognitive impairments in cancer patients that may accelerate cognitive aging. Memory is particularly affected in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27c03603da712f50620bb8fb2ea7c69
https://europepmc.org/articles/PMC5294923/
https://europepmc.org/articles/PMC5294923/
Autor:
Bradley L. Nilsson, Lisa A. Opanashuk, Todd M. Doran, Elizabeth A. Anderson, Sarah E. Latchney
Publikováno v:
Journal of Molecular Biology. 421:315-328
The accumulation of senile plaques composed of amyloid β (Aβ) fibrils is a hallmark of Alzheimer's disease, although prefibrillar oligomeric species are believed to be the primary neurotoxic congeners in the pathogenesis of Alzheimer's disease. Unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb20c0037c8e4a91421be1ac3fcf02d4
https://doi.org/10.1016/j.jmb.2012.01.055
https://doi.org/10.1016/j.jmb.2012.01.055
Autor:
Lisa A. Opanashuk, Daniel P. Dever
Publikováno v:
Molecular Pharmacology. 81:669-678
The aryl hydrocarbon receptor (AhR), a ligand-activated member of the basic helix-loop-helix (bHLH)/PER-ARNT-SIM (PAS) transcription superfamily, is known to regulate the toxicity of polyaromatic halogenated hydrocarbon environmental chemicals, most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9a70603f2cfe777565522ef22d4dc9
https://doi.org/10.1124/mol.111.077305
https://doi.org/10.1124/mol.111.077305
Autor:
Lisa A. Opanashuk, Deborah A. Cory-Slechta, Richard Fitzpatrick, Sarah A. Notter, Mona Thiruchelvam, Donna W. Lee, Daniel P. Dever, Paul J. Kostyniak
Publikováno v:
Toxicological Sciences. 125:496-508
Recent epidemiologic studies have demonstrated a link between organochlorine and pesticide exposure to an enhanced risk for neurodegenerative disorders such as Parkinson’s disease (PD). A common biological phenomenon underlying cell injury associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1cdac08ff2e7037540eb9bf64f41be6
https://doi.org/10.1093/toxsci/kfr313
https://doi.org/10.1093/toxsci/kfr313
Autor:
Mark J. Gallagher, Gary R. Morrow, Robert A. Gross, Michelle C. Janelsins, Lisa A. Opanashuk, Charles E. Heckler, Michel J. Berg, Joseph A. Roscoe, Pascal Jean-Pierre, Bryan D. Thompson
Publikováno v:
Cancer Investigation. 28:544-553
Chemotherapeutic agents produce persistent difficulties in memory through an unknown mechanism. We tested the hypothesis that chemotherapeutic agents readily able to cross the blood–brain barrier (cyclophosphamide and fluorouracil), as opposed to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60678f274632a11e31d08997830ba508
https://doi.org/10.3109/07357900903405942
https://doi.org/10.3109/07357900903405942
Publikováno v:
Biochemical Pharmacology. 77:577-587
The aryl hydrocarbon receptor (AhR) is known mainly as the mediator for the toxicity of certain xenobiotics. However, there is also much information to indicate that this transcription factor has important biological functions. Here we review the evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a90b8fcda0980075aef75937d8e96ac
https://doi.org/10.1016/j.bcp.2008.10.001
https://doi.org/10.1016/j.bcp.2008.10.001