Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lisa A Jung"'
Autor:
Katja Lidschreiber, Lisa A Jung, Henrik von der Emde, Kashyap Dave, Jussi Taipale, Patrick Cramer, Michael Lidschreiber
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 1, Pp 1-23 (2021)
Abstract The growth of human cancer cells is driven by aberrant enhancer and gene transcription activity. Here, we use transient transcriptome sequencing (TT‐seq) to map thousands of transcriptionally active putative enhancers in fourteen human can
Externí odkaz:
https://doaj.org/article/f9845d94031942ae8a720cdf29e6f3fa
Autor:
Gert-Jan Hendriks, Lisa A. Jung, Anton J. M. Larsson, Michael Lidschreiber, Oscar Andersson Forsman, Katja Lidschreiber, Patrick Cramer, Rickard Sandberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Sequencing of newly synthesised RNA can reveal the transcriptional dynamics in a population of cells. Here the authors develop NASC-seq to bring this sensitivity and temporal resolution to single-cell analysis.
Externí odkaz:
https://doaj.org/article/6c2539c49151440bae8f5d6aea33b041
Autor:
Francesca Lorenzin, Uwe Benary, Apoorva Baluapuri, Susanne Walz, Lisa Anna Jung, Björn von Eyss, Caroline Kisker, Jana Wolf, Martin Eilers, Elmar Wolf
Publikováno v:
eLife, Vol 5 (2016)
Enhanced expression of the MYC transcription factor is observed in the majority of tumors. Two seemingly conflicting models have been proposed for its function: one proposes that MYC enhances expression of all genes, while the other model suggests ge
Externí odkaz:
https://doaj.org/article/08ca9d24a07342828b1f83f19aa22834
Autor:
Jussi Taipale, Michael Lidschreiber, Patrick Cramer, Henrik von der Emde, Katja Lidschreiber, Kashyap Dave, Lisa A. Jung
Publikováno v:
Molecular Systems Biology
Molecular Systems Biology, Vol 17, Iss 1, Pp n/a-n/a (2021)
Molecular Systems Biology, Vol 17, Iss 1, Pp n/a-n/a (2021)
The growth of human cancer cells is driven by aberrant enhancer and gene transcription activity. Here, we use transient transcriptome sequencing (TT‐seq) to map thousands of transcriptionally active putative enhancers in fourteen human cancer cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d22994693131da94beac826b11d1bd1
https://hdl.handle.net/21.11116/0000-0008-4CCA-021.11116/0000-0008-4CD1-7
https://hdl.handle.net/21.11116/0000-0008-4CCA-021.11116/0000-0008-4CD1-7
Autor:
Gert-Jan Hendriks, Lisa Anna Jung, Anton J.M. Larsson, Oscar Andersson Forsman, Michael Lidschreiber, Katja Lidschreiber, Patrick Cramer, Rickard Sandberg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a422b470a3c4cee4d378bb60f35ebdf3
https://doi.org/10.17504/protocols.io.whtfb6n
https://doi.org/10.17504/protocols.io.whtfb6n
Autor:
Robert Düster, Martin Eilers, Bikash Adhikari, Shuang-Yan Wang, Ashwin Narain, Elmar Wolf, Susanne Walz, Armin Wiegering, Peter Gallant, Patrick Cramer, Pranjali Bhandare, Andreas Schlosser, Seychelle M. Vos, Julia Hofstetter, Theresa Endres, Apoorva Baluapuri, Hans Michael Maric, Nevenka Dudvarski Stankovic, Matthias Geyer, Jens T. Vanselow, Jessica Denise Schwarz, Lisa Anna Jung, Markus Vogt
Publikováno v:
Molecular Cell
Summary The MYC oncoprotein binds to promoter-proximal regions of virtually all transcribed genes and enhances RNA polymerase II (Pol II) function, but its precise mode of action is poorly understood. Using mass spectrometry of both MYC and Pol II co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93038ca5ddbd93f73c2c72e76403224
https://doi.org/10.1016/j.molcel.2019.02.031
https://doi.org/10.1016/j.molcel.2019.02.031
Autor:
Uwe Benary, Jana Wolf, Francesca Lorenzin, Elmar Wolf, Martin Eilers, Björn von Eyss, Lisa Anna Jung, Caroline Kisker, Apoorva Baluapuri, Susanne Walz
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
Enhanced expression of the MYC transcription factor is observed in the majority of tumors. Two seemingly conflicting models have been proposed for its function: one proposes that MYC enhances expression of all genes, while the other model suggests ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d3ea93892be43c4d3b2d9abbb08d2e
http://edoc.mdc-berlin.de/15872/1/15872oa.pdf
http://edoc.mdc-berlin.de/15872/1/15872oa.pdf
Autor:
Jana Wolf, Susanne Walz, Apoorva Baluapuri, Caroline Kisker, Uwe Benary, Lisa Anna Jung, Björn von Eyss, Francesca Lorenzin, Martin Eilers, Elmar Wolf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dac2018e45b0c594937bb27f1445988c
https://doi.org/10.7554/elife.15161.036
https://doi.org/10.7554/elife.15161.036
Autor:
Elmar Wolf, Gerard I. Evan, Luana D’Artista, Lars Zender, Sebastian Letschert, Lisa Anna Jung, W. Koelmel, Caroline Kisker, Andrew V. Biankin, Markus Sauer, Susanne Walz, B von Eyss, Jochen Kuper, Carsten P. Ade, Martin Eilers, C Redel, Anneli Gebhardt
Publikováno v:
Oncogene. 36(14)
MYC genes have both essential roles during normal development and exert oncogenic functions during tumorigenesis. Expression of a dominant-negative allele of MYC, termed OmoMYC, can induce rapid tumor regression in mouse models with little toxicity f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265c94020530fb3088134edd5dc49608
https://pubmed.ncbi.nlm.nih.gov/27748763
https://pubmed.ncbi.nlm.nih.gov/27748763
Publikováno v:
General and comparative endocrinology. 195
Gonadotropin-releasing hormone (GnRH) plays important roles in vertebrate reproduction. Recently, molecules structurally similar to vertebrate GnRH were discovered in mollusks, including a gastropod, Aplysia californica. As an important step toward u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375955c686ff1328df6548552b4fa8e0
https://pubmed.ncbi.nlm.nih.gov/24246309
https://pubmed.ncbi.nlm.nih.gov/24246309