Výsledky vyhledávání - "Lisa Manzini"

Akademický článek

T cell activation but not polyfunctionality after primary HIV infection predicts control of viral load and length of the time without therapy.

Autor: Andrea Cossarizza, Linda Bertoncelli, Elisa Nemes, Enrico Lugli, Marcello Pinti, Milena Nasi, Sara De Biasi, Lara Gibellini, Jonas P Montagna, Marco Vecchia, Lisa Manzini, Marianna Meschiari, Vanni Borghi, Giovanni Guaraldi, Cristina Mussini

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e50728 (2012)

ObjectiveImmune changes occurring after primary HIV infection (PHI) have a pivotal relevance. Our objective was to characterize the polyfunctionality of immune response triggered by PHI, and to characterize immune activation and regulatory T cells, c

Externí odkaz: https://doaj.org/article/4ef44ddb568c45ffa319473c6ce6d456

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Absence of liver steatosis in HIV–HCV co-infected patients receiving regimens containing tenofovir or abacavir

Autor: Lisa Manzini, Andrea Cossarizza, Luca Bisi, Cristina Mussini, Vanni Borghi

Publikováno v: Infection. 41:425-429

In human immunodeficiency virus-hepatitis C virus (HIV-HCV) co-infected patients, steatosis has been independently associated with a number of antiretroviral drugs, including stavudine, especially in patients with non-3 HCV genotypes. We retrospectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e93c16de7b5e1af5954d1bd743fd00
https://doi.org/10.1007/s15010-012-0378-7

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Increased plasma levels of extracellular mitochondrial DNA during HIV infection: A new role for mitochondrial damage-associated molecular patterns during inflammation

Autor: Tommaso Trenti, Lisa Manzini, Erika Roat, Lara Gibellini, Jonas P. Montagna, Sara De Biasi, Cristina Mussini, Marcello Pinti, Vanni Borghi, Linda Bertoncelli, Andrea Cossarizza, Milena Nasi, Luca Bisi, Serena Manzini

Publikováno v: Mitochondrion. 11:750-755

HIV infection is characterized by a chronic inflammatory state. Recently, it has been shown that mitochondrial DNA (mtDNA) released from damaged or dead cells can bind Toll like receptor-9 (TLR9), an intracellular receptor that responds to bacterial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd369c52802a6db8f6d55f2b9992ec1
https://doi.org/10.1016/j.mito.2011.06.005

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CD4+ T-cell differentiation, regulatory T cells and gag-specific T lymphocytes are unaffected by CD4-guided treatment interruption and therapy resumption

Autor: Andrea Cossarizza, Serena Manzini, Lisa Manzini, Enrico Lugli, Cristina Mussini, Cinzia Del Giovane, Milena Nasi, Linda Bertoncelli, Elisa Nemes, Roberto D'Amico, Francesca Prati, Marcello Pinti

Publikováno v: AIDS (London, England). 25(12)

OBJECTIVES Despite limiting exposure to antiretroviral drugs, structured treatment interruptions can influence multiple aspects of T-cell immunity, particularly those regarding CD4(+) T lymphocytes. We evaluated the impact of CD4-guided treatment int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39de69d45d084547b59435e889d1822d
https://pubmed.ncbi.nlm.nih.gov/21505295

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Cytotoxic granule release dominates gag-specific CD4+ T-cell response in different phases of HIV infection

Autor: Lisa Manzini, Enrico Lugli, Francesca Prati, Serena Manzini, Milena Nasi, Linda Bertoncelli, Elisa Nemes, Andrea Cossarizza, Cristina Mussini, Marcello Pinti, Vanni Borghi

Background The activity of virus-specific T lymphocytes, among which those capable of a polyfunctional response against the viral protein gag, is crucial to control HIV infection. Objective The objective of this study is to investigate the polyfuncti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a9834076cf3a165b0adde36908fc28
https://hdl.handle.net/11380/640574

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Predictive Value of Intracellular HIV-1 DNA Levels During CD4-Guided Treatment Interruption in HIV(+) Patients

Autor: Lisa Manzini, Lara Gibellini, Luca Bisi, Cristina Mussini, Vanni Borghi, Sara De Biasi, Milena Nasi, Andrea Cossarizza, Cinzia Del Giovane, Serena Manzini, Marcello Pinti, Roberto D'Amico

The amount of HIV-1 DNA within peripheral blood mononuclear cells is an important marker of viral activity. We studied intracellular HIV-1 DNA content in purified CD4(+) T cells from 28 chronically HIV-1-infected adults with sustained CD4(+) T cell c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d901963d07fb64f01366910847fd6a5
https://hdl.handle.net/11380/640893

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T Cell Activation but Not Polyfunctionality after Primary HIV Infection Predicts Control of Viral Load and Length of the Time without Therapy

Autor: Elisa Nemes, Jonas P. Montagna, Vanni Borghi, Lisa Manzini, Marianna Meschiari, Andrea Cossarizza, Milena Nasi, Marco Vecchia, Linda Bertoncelli, Cristina Mussini, Giovanni Guaraldi, Sara De Biasi, Lara Gibellini, Enrico Lugli, Marcello Pinti

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e50728 (2012)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e77b938513453765ca0419efb7e5b1
https://doi.org/10.1371/journal.pone.0050728

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Absence of liver steatosis in HIV-infected patients receiving tenofovir-containing regimen

Autor: Roberto Esposito, Cristina Mussini, Vanni Borghi, Luca Bisi, Lisa Manzini

Publikováno v: Journal of the International AIDS Society. 11:P273

Purpose of the study Liver steatosis is a common and important histological finding in hepatitis C, and is associated with an increased progression of the disease. In HIV co-infected patients, steatosis was independently associated with d-drugs, such

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2255fc50ba3a23709bf38b51092fa04b
https://doi.org/10.1186/1758-2652-11-s1-p273

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