Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Lisa, Richters"'
Autor:
Anja Tüchler, Antoine De Pauw, Corinna Ernst, Amélie Anota, Inge M.M. Lakeman, Julia Dick, Nienke van der Stoep, Christi J. van Asperen, Monika Maringa, Natalie Herold, Britta Blümcke, Robert Remy, Anke Westerhoff, Denise J. Stommel-Jenner, Eléonore Frouin, Lisa Richters, Lisa Golmard, Nadine Kütting, Chrystelle Colas, Barbara Wappenschmidt, Kerstin Rhiem, Peter Devilee, Dominique Stoppa-Lyonnet, Rita K. Schmutzler, Eric Hahnen
Publikováno v:
Breast, Vol 73, Iss , Pp 103615- (2024)
Background: Breast cancer (BC) risk prediction models consider cancer family history (FH) and germline pathogenic variants (PVs) in risk genes. It remains elusive to what extent complementation with polygenic risk score (PRS) and non-genetic risk fac
Externí odkaz:
https://doaj.org/article/f91dd96772b24b38a3d25235b52f3750
Autor:
Nana Weber-Lassalle, Julika Borde, Konstantin Weber-Lassalle, Judit Horváth, Dieter Niederacher, Norbert Arnold, Silke Kaulfuß, Corinna Ernst, Victoria G. Paul, Ellen Honisch, Kristina Klaschik, Alexander E. Volk, Christian Kubisch, Steffen Rapp, Nadine Lichey, Janine Altmüller, Louisa Lepkes, Esther Pohl-Rescigno, Holger Thiele, Peter Nürnberg, Mirjam Larsen, Lisa Richters, Kerstin Rhiem, Barbara Wappenschmidt, Christoph Engel, Alfons Meindl, Rita K. Schmutzler, Eric Hahnen, Jan Hauke
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-6 (2019)
Abstract Background The role of the BARD1 gene in breast cancer (BC) and ovarian cancer (OC) predisposition remains elusive, as published case-control investigations have revealed controversial results. We aimed to assess the role of deleterious BARD
Externí odkaz:
https://doaj.org/article/6542c7dcf6614ef1973c45fb57592c84
Autor:
Nana Weber-Lassalle, Jan Hauke, Juliane Ramser, Lisa Richters, Eva Groß, Britta Blümcke, Andrea Gehrig, Anne-Karin Kahlert, Clemens R. Müller, Karl Hackmann, Ellen Honisch, Konstantin Weber-Lassalle, Dieter Niederacher, Julika Borde, Holger Thiele, Corinna Ernst, Janine Altmüller, Guido Neidhardt, Peter Nürnberg, Kristina Klaschik, Christopher Schroeder, Konrad Platzer, Alexander E. Volk, Shan Wang-Gohrke, Walter Just, Bernd Auber, Christian Kubisch, Gunnar Schmidt, Judit Horvath, Barbara Wappenschmidt, Christoph Engel, Norbert Arnold, Bernd Dworniczak, Kerstin Rhiem, Alfons Meindl, Rita K. Schmutzler, Eric Hahnen
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-6 (2018)
Abstract Background Germline mutations in the BRIP1 gene have been described as conferring a moderate risk for ovarian cancer (OC), while the role of BRIP1 in breast cancer (BC) pathogenesis remains controversial. Methods To assess the role of delete
Externí odkaz:
https://doaj.org/article/951e74b0cfc6446ab5113f955636b95b
Autor:
Philipp Harter, Jan Hauke, Florian Heitz, Alexander Reuss, Stefan Kommoss, Frederik Marmé, André Heimbach, Katharina Prieske, Lisa Richters, Alexander Burges, Guido Neidhardt, Nikolaus de Gregorio, Ahmed El-Balat, Felix Hilpert, Werner Meier, Rainer Kimmig, Karin Kast, Jalid Sehouli, Klaus Baumann, Christian Jackisch, Tjoung-Won Park-Simon, Lars Hanker, Sandra Kröber, Jacobus Pfisterer, Heidrun Gevensleben, Andreas Schnelzer, Dimo Dietrich, Tanja Neunhöffer, Mathias Krockenberger, Sara Y Brucker, Peter Nürnberg, Holger Thiele, Janine Altmüller, Josefin Lamla, Gabriele Elser, Andreas du Bois, Eric Hahnen, Rita Schmutzler
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186043 (2017)
Identification of families at risk for ovarian cancer offers the opportunity to consider prophylactic surgery thus reducing ovarian cancer mortality. So far, identification of potentially affected families in Germany was solely performed via family h
Externí odkaz:
https://doaj.org/article/939baee6a8de4d379fefaf2e08e2274a
Autor:
Mohamad Kayali, Jan Hauke, Nikolaus de Gregorio, Rita K. Schmutzler, Jalid Sehouli, Corinna Ernst, Ahmed El-Balat, Rainer Kimmig, Holger Thiele, Philipp Harter, Dimo Dietrich, Lisa Richters, Alexander Burges, Eric Hahnen, Werner Meier, Heidrun Gevensleben, Birgid Schoemig-Markiefka, Felix Hilpert, Karin Kast, Alexander Reuss, Peter Nürnberg, Sandra Schmidt, Julika Borde, André Heimbach, Janine Altmüller
Publikováno v:
Journal of Medical Genetics. 59:248-252
Variant-specific loss of heterozygosity (LOH) analyses may be useful to classify BRCA1/2 germline variants of unknown significance (VUS). The sensitivity and specificity of this approach, however, remains unknown. We performed comparative next-genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de010caa779c05ccfe9bbd364ce35aeb
https://doi.org/10.1136/jmedgenet-2020-107353
https://doi.org/10.1136/jmedgenet-2020-107353
Autor:
Esther Scheerman, Carolien H.M. van Deurzen, Agnes Jager, Philipp Harter, Dimo Dietrich, Ewald van Dijk, Sandra Schmidt, Philip C. Schouten, Esther H. Lips, Stefan Kommoss, Roelof J.C. Kluin, Rita K. Schmutzler, Petra M. Nederlof, Lodewyk F. A. Wessels, Patricia C. Ewing-Graham, Daniel J. Vis, Frederik Marmé, Andreas du Bois, Jan Hauke, Nikolaus de Gregorio, Sabine C. Linn, Alexander Burges, Corinna Ernst, Lisa Richters, Katharina Prieske, Eric Hahnen
Publikováno v:
Clinical Cancer Research, 27(23), 6559-6569. American Association for Cancer Research Inc.
Clinical Cancer Research, 27(23)
Clinical Cancer Research, 27(23)
Purpose: Previously, we developed breast cancer BRCA1-like and BRCA2-like copy-number profile shrunken centroid classifiers predictive for mutation status and response to therapy, targeting homologous recombination deficiency (HRD). Therefore, we inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f92748eeb27c5de29c2a3cf5c927e2
https://pure.eur.nl/en/publications/b119872f-aea2-46e5-ae94-0a8a60a46639
https://pure.eur.nl/en/publications/b119872f-aea2-46e5-ae94-0a8a60a46639
Autor:
H Haverkamp, U. Nitz, R Kates, Matthias Christgen, Lisa Richters, E-M. Grischke, S. Kuemmel, Rachel Wuerstlein, O Gluz, H.H. Kreipe, Nana Weber-Lassalle, Monika Graeser, Corinna Ernst, M Kayali, Michael Braun, R Schmutzler, Jan Hauke, Nadia Harbeck, Eric Hahnen, M. Warm
Publikováno v:
Senologie - Zeitschrift für Mammadiagnostik und -therapie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf104d4d595a25b54b94824f05adf69a
https://doi.org/10.1055/s-0041-1730212
https://doi.org/10.1055/s-0041-1730212
Autor:
Wolfram Malter, Verena Kirn, Lisa Richters, Claudius Fridrich, Birgid Markiefka, Rudolf Bongartz, Robert Semrau, Peter Mallmann, Stefan Kraemer
Publikováno v:
International Journal of Breast Cancer, Vol 2014 (2014)
Breast-conserving surgery followed by whole-breast irradiation is the standard local therapy for early breast cancer. The international discussion of reduced importance of wider tumor-free resection margins than “tumor not touching ink” leads to
Externí odkaz:
https://doaj.org/article/3f98291d62be4265bfb690e3aefa1538
Autor:
Philip C, Schouten, Lisa, Richters, Daniel J, Vis, Stefan, Kommoss, Ewald, van Dijk, Corinna, Ernst, Roelof J C, Kluin, Frederik, Marmé, Esther H, Lips, Sandra, Schmidt, Esther, Scheerman, Katharina, Prieske, Carolien H M, van Deurzen, Alexander, Burges, Patricia C, Ewing-Graham, Dimo, Dietrich, Agnes, Jager, Nikolaus, de Gregorio, Jan, Hauke, Andreas, du Bois, Petra M, Nederlof, Lodewyk F, Wessels, Eric, Hahnen, Philipp, Harter, Sabine C, Linn, Rita K, Schmutzler
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(23)
Previously, we developed breast cancerThe detection rate of theThe newly trained classifiers detected most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80471f361c32c97d5fe4a66d0101b2b4
https://pubmed.ncbi.nlm.nih.gov/34593530
https://pubmed.ncbi.nlm.nih.gov/34593530
Autor:
Margarete Odenthal, Leonie Strake, Ulrike Koitzsch, Fabinshy Thangarajah, Lisa Richters, Verena Kirn, Jochen W.U. Fries, Hannah Eischeid
Publikováno v:
Clinical & Experimental Metastasis. 35:707-712
The role of ESR1 methylation in breast cancer and its influence on disease progression is not yet fully understood. Healthy breast tissue usually does not show ESR1 promoter methylation, whereas the frequency of ESR1 methylation appears to increase i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac07381086092c3a4bba6b18a29c0cf
https://doi.org/10.1007/s10585-018-9935-5
https://doi.org/10.1007/s10585-018-9935-5