Výsledky vyhledávání - "Lisa, Parfitt"

The spectrum of pulmonary arterial hypertension in adults with congenital heart disease: management from a physician and nurse specialist perspective

Autor: Konstantinos Dimopoulos, Carl Harries, Lisa Parfitt

Publikováno v: Journal of Congenital Cardiology, Vol 1, Iss 1, Pp 1-9 (2017)

Congenital heart disease (CHD) is one of the most common causes of pulmonary arterial hypertension (PAH), with a prevalence nearing that of idiopathic PAH in registries. Despite similarities in pulmonary vascular pathology, PAH-CHD differs from idiop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845eaa348785f68dfe4a4cd46b7c2579
http://link.springer.com/article/10.1186/s40949-017-0006-6

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Growth/differentiation factor 15 causes TGFβ-activated kinase 1-dependent muscle atrophy in pulmonary arterial hypertension

Autor: Benjamin E, Garfield, Alexi, Crosby, Dongmin, Shao, Peiran, Yang, Cai, Read, Steven, Sawiak, Stephen, Moore, Lisa, Parfitt, Carl, Harries, Martin, Rice, Richard, Paul, Mark L, Ormiston, Nicholas W, Morrell, Michael I, Polkey, Stephen John, Wort, Paul R, Kemp

Publikováno v: Thorax. 74(2)

Skeletal muscle dysfunction is a clinically important complication of pulmonary arterial hypertension (PAH). Growth/differentiation factor 15 (GDF-15), a prognostic marker in PAH, has been associated with muscle loss in other conditions. We aimed to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::99568eb8a9b4d1131943a42a1f49529b
https://pubmed.ncbi.nlm.nih.gov/30554140

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Disease targeting therapies in patients with Eisenmenger syndrome: Response to treatment and long-term efficiency

Autor: Konstantinos Dimopoulos, Aleksander Kempny, Rafael Alonso-Gonzalez, Stephen J. Wort, Gerhard-Paul Diller, Philip Marino, Lisa Parfitt, Carl Harries, Chiehyang Koo, Michael A. Gatzoulis, Lorna Swan, Maria Alvarez-Barredo, Anselm Uebing

Publikováno v: International Journal of Cardiology. 167:840-847

Objectives To examine long-term efficacy of disease targeting therapies (DTT) in patients with Eisenmenger syndrome. Methods All adult patients with Eisenmenger syndrome treated with DTT at our institution were included. Functional class (FC), oxygen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca044be240350a6c90593f777fe7f268
https://doi.org/10.1016/j.ijcard.2012.02.007

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Intravenous prostacyclin for pulmonary hypertension: Patient's perspective on complications

Autor: Kostas Dimopoulos, John Wort, Laura C. Price, Michael A. Gatzoulis, Arif Khokhar, Rafa Alonso, Ann Sturdy, Carl Harries, Lisa Parfitt, Sara Tyebally

Publikováno v: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases.

Introduction: Intravenous (IV) prostacyclin therapy in patients with severe pulmonary arterial hypertension can be associated with life-threatening complications. Patient education and confidence in local healthcare services is critical to ensuring p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb37a89957c971e8de937ff5b7e163d1
https://doi.org/10.1183/13993003.congress-2016.pa2481

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The use of sildenafil to treat pulmonary hypertension associated with interstitial lung disease

Autor: Carl Harries, Michael A. Gatzoulis, Lisa Parfitt, Tamera J. Corte, Athol U. Wells, S. John Wort

Publikováno v: Respirology. 15:1226-1232

Background and objective: Limited data suggest a benefit following sildenafil treatment in patients with pulmonary hypertension (PH) and interstitial lung disease (ILD). The role of sildenafil in the management of PH in ILD is not clear. We report ou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94b2fe79252ddd30bf4f3c392fe28e5b
https://doi.org/10.1111/j.1440-1843.2010.01860.x

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Is sildenafil an effective bridging therapy to lung transplantation for patients with pulmonary hypertension in the setting of lung disease?

Autor: Lisa Parfitt, Carl Harries, Laura C. Price, John Wort, Kostantinos Dimopoulos, Martin Carby, Aleksander Kempny, Raphael Alonso, Athol U. Wells, Anna Reed, Andre R. Simon

Publikováno v: 4.3 Pulmonary Circulation and Pulmonary Vascular Disease.

Aims and objectives: Pulmonary hypertension (PH) is a feature of patients with lung disease undergoing lung transplantation (LTx). Sildenafil use in these patients with 9group 39 PH is not routine, although it appears to benefit some patients. In add

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4f4825dd8271865be785a06f9641b89
https://doi.org/10.1183/13993003.congress-2015.pa3765

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The role of growth and differentiation factor 15 (GDF-15) in the development of skeletal muscle wasting in pulmonary arterial hypertension (PAH)

Autor: Nicholas W. Morrell, Lee Jen, Dongmin Shao, S. John Wort, Alexi Crosby, Yang Pieran, Lisa Parfitt, Paul R. Kemp, Carl Harries, Michael I. Polkey, Benjamin Garfield

Publikováno v: 1.2 Rehabilitation and Chronic Care.

Introduction: Skeletal muscle wasting is emerging as an important complication of PAH. GDF-15, a TGFbeta ligand, has been implicated in the development of muscle wasting and is a marker of prognosis in PAH. It may be a potential target for therapeuti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a6c951a3c0f0f7215f26dd923d09be7
https://doi.org/10.1183/13993003.congress-2015.pa4608

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Relation of the novel pulmonary hypertension emPHasis10 quality of life score to markers of disease severity

Autor: Marina Revilla-Martinez, Aleksander Kempny, Lisa Parfitt, John Wort, Laura C. Price, Rafael Alonso-Gonzalez, Beatriz García-Aranda, Carl Harries, K Dimopoulos

Publikováno v: 4.3 Pulmonary Circulation and Pulmonary Vascular Disease.

Background EMPHASIS10 is a novel, easy to use quality of life questionnaire designed for patients with pulmonary hypertension (PH) 1 . We report our experience in using this score and its relation to markers of disease severity. Methods and Results I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::800188e57448dde9f3fef603e57a4805
https://doi.org/10.1183/13993003.congress-2015.pa3776

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