Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lisa, Kain"'
Autor:
Hao Hu, Anthony N. Vomund, Orion J. Peterson, Neetu Srivastava, Tiandao Li, Lisa Kain, Wandy L. Beatty, Bo Zhang, Chyi-Song Hsieh, Luc Teyton, Cheryl F. Lichti, Emil R. Unanue, Xiaoxiao Wan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Autoimmune attack toward pancreatic β cells causes permanent loss of glucose homeostasis in type 1 diabetes (T1D). Insulin secretory granules store and secrete insulin but are also thought to be tissue messengers for T1D. Here, we show that
Externí odkaz:
https://doaj.org/article/38e4150b7348442bba37d66dcf1cb948
Autor:
Carla Kirschbaum, Kim Greis, Eike Mucha, Lisa Kain, Shenglou Deng, Andreas Zappe, Sandy Gewinner, Wieland Schöllkopf, Gert von Helden, Gerard Meijer, Paul B. Savage, Mateusz Marianski, Luc Teyton, Kevin Pagel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Glycolipids are glycoconjugates with important biological functions, but techniques for their analysis are deficient. Here, the authors report the use of cryogenic gas-phase infrared spectroscopy to investigate isomerism in a set of immunologically r
Externí odkaz:
https://doaj.org/article/a21a464c5dbd442ba4a70c62e515703b
Autor:
Carla, Kirschbaum, Kim, Greis, Eike, Mucha, Lisa, Kain, Shenglou, Deng, Andreas, Zappe, Sandy, Gewinner, Wieland, Schöllkopf, Gert, von Helden, Gerard, Meijer, Paul B, Savage, Mateusz, Marianski, Luc, Teyton, Kevin, Pagel
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Glycolipids are complex glycoconjugates composed of a glycan headgroup and a lipid moiety. Their modular biosynthesis creates a vast amount of diverse and often isomeric structures, which fulfill highly specific biological functions. To date, no gold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::27e163f4a6ce607a21e1e4451eee9b1a
https://hdl.handle.net/21.11116/0000-0008-0874-D21.11116/0000-0008-08AB-F
https://hdl.handle.net/21.11116/0000-0008-0874-D21.11116/0000-0008-08AB-F
Autor:
Brian T. Abe, Siddhartha Sharma, Lisa Kain, Andrew I. Su, Anne Costanzo, Louis Gioia, Marie Holt, Luc Teyton
Publikováno v:
Molecular Immunology. 103:191-199
The difficulty of studying small tissue samples and rare cell populations have been some of the main limitations in performing efficient translational studies of immune mediated diseases. Many of these conditions are grouped under the name of a singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7d61f009d65e301ed5fbd8370a9c45
https://doi.org/10.1016/j.molimm.2018.09.020
https://doi.org/10.1016/j.molimm.2018.09.020
Autor:
Lisa Kain, Juan Carlos Zúñiga-Pflücker, David L. Wiest, Roland L. Dunbrack, Francis Coffey, Payam Zarin, Luc Teyton, Shawn P. Fahl, Dietmar J. Kappes
Publikováno v:
Proceedings of the National Academy of Sciences. 115:1889-1894
Unlike αβ-T lineage cells, where the role of ligand in intrathymic selection is well established, the role of ligand in the development of γδ-T cells remains controversial. Here we provide evidence for the role of a bona fide selecting ligand in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0402393808d5429d22805191179921
https://doi.org/10.1073/pnas.1718328115
https://doi.org/10.1073/pnas.1718328115
Autor:
Macedo Mf, Lisa Kain, Luc Teyton, Shenglou Deng, Albert Bendelac, S. Mata, Catia S. Pereira, Paul B. Savage
Publikováno v:
Chemical Science. 8:2204-2208
Natural killer T (NKT) cells play a central role in the interface between innate and adaptive immunity, and alpha-galactosylceramide was recently shown to be an endogenous antigen for these cells. The source of alpha-galactosylceramide has not yet be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c4fca7df3c4dc28849c5f60fc2e61ed
https://doi.org/10.1039/c6sc04218j
https://doi.org/10.1039/c6sc04218j
Autor:
Maki Nakayama, Yi-Guang Chen, Anne Costanzo, Emil R. Unanue, Louis Gioia, Clayton E. Mathews, Andrew I. Su, Xiaoxiao Wan, Marie Holt, Brian T. Abe, Lisa Kain, Siddhartha Sharma, Luc Teyton
Publikováno v:
Science Immunology. 4
The class II region of the major histocompatibility complex (MHC) locus is the main contributor to the genetic susceptibility to type 1 diabetes (T1D). The loss of an aspartic acid at position 57 of diabetogenic HLA-DQβ chains supports this associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa17037bcc8474a4415597f2e479976f
https://doi.org/10.1126/sciimmunol.aaw6329
https://doi.org/10.1126/sciimmunol.aaw6329
Autor:
Siddhartha Sharma, Lisa Kain, Anne Costanzo, Louis Gioia, Brian T. Abe, Luc Teyton, Andrew I. Su, Marie Holt
Publikováno v:
Molecular immunology. 107
The difficulty of studying small tissue samples and rare cell populations have been some of the main limitations in performing efficient translational studies of immune mediated diseases. Many of these conditions are grouped under the name of a singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f09be2c192c966cde0c0c64ad1e2cf
https://pubmed.ncbi.nlm.nih.gov/30300798
https://pubmed.ncbi.nlm.nih.gov/30300798
Autor:
Louis, Gioia, Marie, Holt, Anne, Costanzo, Siddhartha, Sharma, Brian, Abe, Lisa, Kain, Maki, Nakayama, Xiaoxiao, Wan, Andrew, Su, Clayton, Mathews, Yi-Guang, Chen, Emil, Unanue, Luc, Teyton
Publikováno v:
Science immunology. 4(38)
The class II region of the Major Histocompatibility locus is the main contributor to the genetic susceptibility to type 1 diabetes (T1D). The loss of an aspartic acid at position 57 of diabetogenic HLA-DQβ chains supports this association; it influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f6191a243490e0071fab5e1d8b95ca1
https://pubmed.ncbi.nlm.nih.gov/31471352
https://pubmed.ncbi.nlm.nih.gov/31471352
Publikováno v:
Molecular Immunology. 68:94-97
The nature of the endogenous ligands for natural killer T (NKT) cells has been debated for more than a decade. Because the mammalian glycosylceramide synthases are invertases, it is believed that in mammals all glycosylceramides are β anomers. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320435617580e8b66ec1ccb73bf190dd
https://doi.org/10.1016/j.molimm.2015.06.009
https://doi.org/10.1016/j.molimm.2015.06.009