Výsledky vyhledávání - "Lis N Velásquez"

Akademický článek

B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway.

Autor: M Ayelén Milillo, Lis N Velásquez, Aldana Trotta, M Victoria Delpino, Fábio V Marinho, Luciana Balboa, Mónica Vermeulen, Sonia L Espindola, Nahuel Rodriguez-Rodrigues, Gabriela C Fernández, Sergio Costa Oliveira, Guillermo H Giambartolomei, Paula Barrionuevo

Publikováno v: PLoS Pathogens, Vol 13, Iss 8, p e1006527 (2017)

Despite eliciting a potent CD8+ T cell response, Brucella abortus is able to persist and establish a chronic infection inside its host. We have previously reported that the infection of human monocytes/macrophages with B. abortus inhibits the IFN-γ-

Externí odkaz: https://doaj.org/article/7891cb24c924458f9432aa2e45d3c711

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Microbial RNA, the New PAMP of Many Faces

Autor: M. Ayelén Milillo, Lis N. Velásquez, Paula Barrionuevo

Publikováno v: Frontiers in Tropical Diseases. 3

Traditionally, pathogen-associated molecular patterns (PAMPs) were described as structural molecular motifs shared by different classes of microorganisms. However, it was later discovered that the innate immune system is also capable of distinguishin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30586e1c6cf23c65783dbbdf09897fda
https://doi.org/10.3389/fitd.2022.924719

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Brucella abortus down-regulates MHC class II by the IL-6-dependent inhibition of CIITA through the downmodulation of IFN regulatory factor-1 (IRF-1)

Autor: Luciana Balboa, Lis N. Velásquez, Paula Barrionuevo, Guillermo H. Giambartolomei, Pablo Fernández, M. Victoria Delpino, Roland Lang, M. Ayelén Milillo, Roberto Gabriel Pozner, Aldana Trotta

Publikováno v: Journal of Leukocyte Biology. 101:759-773

Brucella abortus is an intracellular pathogen capable of surviving inside of macrophages. The success of B. abortus as a chronic pathogen relies on its ability to orchestrate different strategies to evade the adaptive CD4+ T cell responses that it el

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f3c78a763b1208a9556b9a618a5de5
https://doi.org/10.1189/jlb.4a0416-196r

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Platelets promote Brucella abortus monocyte invasion by establishing complexes with monocytes

Autor: Lis N. Velásquez, M. Ayelén Milillo, M. Victoria Delpino, Ana M. Rodríguez, Roberto Gabriel Pozner, Paula Barrionuevo, Verónica I Landoni, Guillermo H. Giambartolomei, Aldana Trotta

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)

Brucellosis is an infectious disease elicited by bacteria of the genus Brucella. Platelets have been extensively described as mediators of hemostasis and responsible for maintaining vascular integrity. Nevertheless, they have been recently involved i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74735ddb559937caa6ab75294704f75
http://journal.frontiersin.org/article/10.3389/fimmu.2018.01000/full

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Adrenal Steroids Modulate the Immune Response during Brucella abortus Infection by a Mechanism That Depends on the Regulation of Cytokine Production

Autor: Lis N. Velásquez, María Virginia Gentilini, Paula Barrionuevo, Paula Constanza Arriola Benitez, María Victoria Delpino, Guillermo H. Giambartolomei

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Human brucellosis is a protean disease with a diversity of clinical signs and symptoms resulting from infection with Brucella species. Recent reports suggest a cross-regulation between adrenal steroids (cortisol and dehydroepiandrosterone [DHEA]) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c46d37979cea69620d34c818e01b055
https://doi.org/10.1128/iai.03090-14

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B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway

Autor: Guillermo H. Giambartolomei, M. Victoria Delpino, Luciana Balboa, Fábio V. Marinho, Lis N. Velásquez, Aldana Trotta, M. Ayelén Milillo, Nahuel Rodriguez-Rodrigues, Paula Barrionuevo, Sonia Espindola, Sergio C. Oliveira, Mónica Vermeulen, Gabriela C. Fernández

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 8, p e1006527 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55cc45b0a3a364a724f8e129652efdd5
http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006527

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Inhibition of MHC-I by Brucella abortus is an early event during infection and involves EGFR pathway

Autor: Patricia V. Elizalde, Roxana Schillaci, Guillermo H. Giambartolomei, Lis N. Velásquez, Aldana Trotta, Roberto Gabriel Pozner, M. Ayelén Milillo, M. Victoria Delpino, M Florencia Mercogliano, Paula Barrionuevo

Publikováno v: Immunology and cell biology. 95(4)

Brucella abortus is able to persist inside the host despite the development of potent CD8+ T-cell responses. We have recently reported the ability of B. abortus to inhibit the interferon-γ-induced major histocompatibility complex (MHC)-I cell surfac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79ae81b776287dc166d8ab1f0e44adf
https://pubmed.ncbi.nlm.nih.gov/27811842

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Brucella abortusinduces intracellular retention of MHC-I molecules in human macrophages down-modulating cytotoxic CD8+T cell responses

Autor: Guillermo H. Giambartolomei, Roberto Gabriel Pozner, Paula Barrionuevo, Lis N. Velásquez, Juliana Cassataro, M. Victoria Delpino

Publikováno v: Cellular Microbiology. 15:487-502

Brucella abortus elicits a vigorous Th1 immune response which activates cytotoxic T lymphocytes. However, B. abortus persists in its hosts in the presence of CD8(+) T cells, establishing a chronic infection. Here, we report that B. abortus infection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33fdb3e8005d2bf1d29f27bc964759d4
https://doi.org/10.1111/cmi.12058

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Brucella abortus induces apoptosis of human T lymphocytes

Autor: Paula Barrionuevo, Romina Scian, Juliana Cassataro, Lis N. Velásquez, Lorena M. Coria, M. Cruz Miraglia, Andrés E. Ibañez, Guillermo H. Giambartolomei, M. Victoria Delpino

Publikováno v: Microbes and Infection. 14:639-650

Immune evasion is essential for Brucella abortus to survive in the face of robust adaptive CD4+ T cell response. We have previously demonstrated that B. abortus can indirectly inhibit CD4+ T cells by down-regulating MHC-II expression and antigen pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8972135f9ab81edc7598edd1c6753398
https://doi.org/10.1016/j.micinf.2012.02.004

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Brucella abortus inhibits IFN-γ-induced FcγRI expression and FcγRI-restricted phagocytosis via toll-like receptor 2 on human monocytes/macrophages

Autor: María Eugenia Rodríguez, Juliana Cassataro, Lorena M. Coria, Guillermo H. Giambartolomei, Andrés E. Ibañez, Lis N. Velásquez, M. Victoria Delpino, Paula Barrionuevo, Clara García Samartino

Publikováno v: Microbes and Infection. 13:239-250

The strategies that allow Brucella abortus to persist for years inside macrophages subverting host immune responses are not completely understood. Immunity against this bacterium relies on the capacity of IFN-γ to activate macrophages, endowing them

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc5388cd1272ca616903e1ffb34c9cb
https://doi.org/10.1016/j.micinf.2010.10.020

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