Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Liron Elkouby"'
Autor:
Liron Elkouby, Sean M. Armour, Raffaella Toso, Marti DiPietro, Robert J. Davidson, Giang N. Nguyen, Mallory Willet, Stephanie Kutza, Joseph Silverberg, Jennifer Frick, Marco Crosariol, Yuhuan Wang, Chuansong Wang, Katherine A. High, Denise E. Sabatino, Xavier M. Anguela
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 20-29 (2022)
Extensive clinical data from liver-mediated gene therapy trials have shown that dose-dependent immune responses against the vector capsid may impair or even preclude transgene expression if not managed successfully with prompt immune suppression. The
Externí odkaz:
https://doaj.org/article/8d15f9b5838e44d49c75621a886fa6f5
Autor:
Sean M. Armour, Mallory Willet, Marti A. DiPietro, Marco Crosariol, Stephanie Kutza, Raffaella Toso, Chuansong Wang, Katherine A. High, Robert J. Davidson, Jennifer Frick, Xavier M. Anguela, Liron Elkouby, Yuhuan Wang, Giang N. Nguyen, Denise E. Sabatino, Joseph Silverberg
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss, Pp 20-29 (2022)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Extensive clinical data from liver-mediated gene therapy trials have shown that dose-dependent immune responses against the vector capsid may impair or even preclude transgene expression if not managed successfully with prompt immune suppression. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46d008ab8ca27b5957160e1cc9ae294
https://doi.org/10.1016/j.omtm.2021.11.005
https://doi.org/10.1016/j.omtm.2021.11.005
Publikováno v:
Cell and Tissue Research. 333:427-438
Members of the claudin family of proteins are the main components of tight junctions (TJs), the major selective barrier of the paracellular pathway between epithelial cells. Selectivity and specificity of TJ strands are determined by the type of clau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf33d591c5682654da756744de6dcb5c
https://doi.org/10.1007/s00441-008-0621-9
https://doi.org/10.1007/s00441-008-0621-9
Autor:
Neta Holland, Liron Elkouby, Rivka Elbaum, Sigal Savaldi-Goldstein, Yulia Fridman, Kristina Vragović
Publikováno v:
Genesdevelopment. 28(8)
Coherent plant growth requires spatial integration of hormonal pathways and cell wall remodeling activities. However, the mechanisms governing sensitivity to hormones and how cell wall structure integrates with hormonal effects are poorly understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc4710c57f8c2b7e2b51ec4c3a7badc9
https://pubmed.ncbi.nlm.nih.gov/24736847
https://pubmed.ncbi.nlm.nih.gov/24736847
Autor:
Alex Tai, Federico Mingozzi, J F Wright, Carolann Howard, Daniel J. Hui, Giulia Pavani, Christian Hinderer, Yifeng Chen, Xavier M. Anguela, Gregory M. Podsakoff, Liron Elkouby, Armida Faella, Robert J. Davidson, Shangzhen Zhou, Etiena Basner-Tschakarjan, Katherine A. High, Mustafa N. Yazicioglu
Publikováno v:
Sci Transl Med
Sci Transl Med, 2013, 5 (194), pp.194ra92. ⟨10.1126/scitranslmed.3005795⟩
Sci Transl Med, 2013, 5 (194), pp.194ra92. ⟨10.1126/scitranslmed.3005795⟩
International audience; Adeno-associated virus (AAV) vectors delivered through the systemic circulation successfully transduce various target tissues in animal models. However, similar attempts in humans have been hampered by the high prevalence of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c78c7b567348c1e6cc35478e67f6de4
https://hal.archives-ouvertes.fr/hal-02881152
https://hal.archives-ouvertes.fr/hal-02881152
Autor:
Robert J. Davidson, Marti A. DiPietro, Katherine A. High, Denise E. Sabatino, Xavier M. Anguela, Raffaella Toso, Liron Elkouby
Publikováno v:
Molecular Therapy. 24:S52
Adeno-associated viral (AAV) vector delivery of factor VIII (FVIII) has been challenging due to its intrinsic properties that result in inefficient expression compared to similarly sized proteins. Early studies of AAV delivery in hemophilia A mice an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c4f59cfeed4c50ee00518bad55cafb2
https://doi.org/10.1016/s1525-0016(16)32861-1
https://doi.org/10.1016/s1525-0016(16)32861-1
Autor:
Liron, Elkouby-Naor, Tamar, Ben-Yosef
Publikováno v:
International review of cell and molecular biology. 279
Members of the claudin family of proteins are the main components of tight junctions (TJs), the major selective barrier of the paracellular pathway between epithelial cells. As such, the claudins have the ability to generate the TJ physiological barr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::033d40989ad6a3241a2acd5aaf5d6e14
https://pubmed.ncbi.nlm.nih.gov/20797675
https://pubmed.ncbi.nlm.nih.gov/20797675
Autor:
Liron Elkouby-Naor, Tamar Ben-Yosef
Members of the claudin family of proteins are the main components of tight junctions (TJs), the major selective barrier of the paracellular pathway between epithelial cells. As such, the claudins have the ability to generate the TJ physiological barr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bb09f53805791264b54c86fc911fab5
https://doi.org/10.1016/s1937-6448(10)79001-8
https://doi.org/10.1016/s1937-6448(10)79001-8
Autor:
Xavier M. Anguela, Liron Elkouby, Marti DiPietro, Katherine A. High, Raffaella Toso, Robert J. Davidson, Denise E. Sabatino
Publikováno v:
Blood. 126:199-199
Clinical studies of adeno-associated viral (AAV)-mediated gene transfer of factor IX for hemophilia B have demonstrated long term expression of therapeutic levels of factor IX but revealed that the AAV vector dose may be limiting due to anti-AAV immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89e7af0000963c742c359efc12347f0e
https://doi.org/10.1182/blood.v126.23.199.199
https://doi.org/10.1182/blood.v126.23.199.199